Zobrazeno 1 - 10
of 112
pro vyhledávání: '"James R. Feramisco"'
Autor:
James R. Feramisco, Axel Schönthal
Publikováno v:
The FOS and JUN Families of Transcription Factors ISBN: 9780203710036
The FOS and JUN Families of Transcription Factors
The FOS and JUN Families of Transcription Factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::631c420cd7f89df25192558b3ae32ccf
https://doi.org/10.1201/9780203710036-21
https://doi.org/10.1201/9780203710036-21
Publikováno v:
Biochemical and Biophysical Research Communications. 384:193-198
The Ser/Thr-specific phosphatase PHLPP (pleckstrin homology domain leucine-rich repeat protein phosphatase) regulates the amplitude and duration of agonist-evoked Akt signaling by dephosphorylating the hydrophobic motif (Ser473) of Akt, therefore ina
Autor:
James R. Feramisco, Tong Tang, Toshitaka Yajima, Atsushi Miyanohara, Mei Hua Gao, Tracy Guo, H. Kirk Hammond, Kersi Pestonjamasp
Publikováno v:
Journal of Biological Chemistry. 283:33527-33535
Increased expression of adenylyl cyclase VI has beneficial effects on the heart, but strategies that increase cAMP production in cardiac myocytes usually are harmful. Might adenylyl cyclase VI have beneficial effects unrelated to increased β-adrener
Autor:
David M. Roth, Hunaid Gurji, Hemal H. Patel, Ashwani Sastry, N. Chin Lai, Atsushi Iwasa, Elizabeth Arnold, James R. Feramisco, Hanh M. Bui, H. Kirk Hammond, Sanjiv M. Narayan, Alborz Hassankhani
Publikováno v:
Journal of the American College of Cardiology. 48:559-565
ObjectivesThe purpose of this study was to test the hypothesis that cardiac-directed expression of adenylyl cyclase VI (ACVI) facilitates atrioventricular (AV) nodal conduction.BackgroundCardiac-directed expression of ACVI, unlike other strategies to
Autor:
James R. Feramisco, Ramy K. Aziz, John T. Buchanan, Malak Kotb, George Y. Liu, Amelia J. Simpson, Victor Nizet, Sascha A. Kristian
Publikováno v:
Buchanan, John T; Simpson, Amelia J; Aziz, Ramy K; Liu, George Y; Kristian, Sascha A; Kotb, Malak; et al.(2006). DNase expression allows the pathogen group A streptococcus to escape killing in neutrophil extracellular traps. Current Biology, 16(4), 396-400. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/08k2q0k0
SummaryThe innate immune response plays a crucial role in satisfactory host resolution of bacterial infection. In response to chemotactic signals, neutrophils are early responding cells that migrate in large numbers to sites of infection. The recent
Autor:
Joseph A. Adams, Gourisankar Ghosh, Jian-Hua Ding, James R. Feramisco, Jonathan C. Hagopian, Xiang-Dong Fu, Marissa M. Cruz, Xiang-Yang Zhong
Publikováno v:
Molecular Biology of the Cell. 17:876-885
Reversible phosphorylation of the SR family of splicing factors plays an important role in pre-mRNA processing in the nucleus. Interestingly, the SRPK family of kinases specific for SR proteins is localized in the cytoplasm, which is critical for nuc
Publikováno v:
Journal of Biological Chemistry. 279:38797-38802
Cardiac-directed expression of adenylyl cyclase type VI (AC(VI)) increases stimulated cAMP production, improves heart function, and increases survival in cardiomyopathy. In contrast, pharmacological agents that increase intracellular levels of cAMP h
Autor:
Hanying Chen, Sylvain Pradervand, Sylvia M. Evans, Siew Yen Ho, James R. Feramisco, Mohammad Pashmforoush, Jonathan T. Lu, Wayne R. Giles, Weinian Shou, Michael Silberbach, Tara R St Amand, Bob Clark, Kenneth R. Chien, D. Woodrow Benson, Richard P. Kondo
Publikováno v:
Cell. 117(3):373-386
Human mutations in Nkx2-5 lead to progressive cardiomyopathy and conduction defects via unknown mechanisms. To define these pathways, we generated mice with a ventricular-restricted knockout of Nkx2-5, which display no structural defects but have pro
Publikováno v:
Molecular Biology of the Cell. 14:4196-4206
Formation of filamentous F-actin drives many cellular processes, including phagocytosis and cell spreading. We have recently reported that mouse macrophage 12/15-lipoxygenase (12/15-LO) activity promotes F-actin formation in filopodia during phagocyt