Zobrazeno 1 - 10
of 29
pro vyhledávání: '"James R. Byrnes"'
Autor:
Thomas G. Bartholow, Paul W.W. Burroughs, Susanna K. Elledge, James R. Byrnes, Lisa L. Kirkemo, Virginia Garda, Kevin K. Leung, James A. Wells
Publikováno v:
ACS Central Science, Vol 10, Iss 1, Pp 199-208 (2023)
Externí odkaz:
https://doaj.org/article/467e7849bb1545af957ab89503b40167
Autor:
James R. Byrnes, Xin X. Zhou, Irene Lui, Susanna K. Elledge, Jeff E. Glasgow, Shion A. Lim, Rita P. Loudermilk, Charles Y. Chiu, Taia T. Wang, Michael R. Wilson, Kevin K. Leung, James A. Wells
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread around the world, there is an urgent need for new assay formats to characterize the humoral response to infection. Here, we present an efficient, competitive
Externí odkaz:
https://doaj.org/article/37d9f89d63ed4f75ab01f6157803f4a4
Autor:
Colin R. Zamecnik, Jayant V. Rajan, Kevin A. Yamauchi, Sabrina A. Mann, Rita P. Loudermilk, Gavin M. Sowa, Kelsey C. Zorn, Bonny D. Alvarenga, Christian Gaebler, Marina Caskey, Mars Stone, Philip J. Norris, Wei Gu, Charles Y. Chiu, Dianna Ng, James R. Byrnes, Xin X. Zhou, James A. Wells, Davide F. Robbiani, Michel C. Nussenzweig, Joseph L. DeRisi, Michael R. Wilson
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100123- (2020)
Summary: Comprehensive understanding of the serological response to SARS-CoV-2 infection is important for both pathophysiologic insight and diagnostic development. Here, we generate a pan-human coronavirus programmable phage display assay to perform
Externí odkaz:
https://doaj.org/article/fb798e3575304cdbbba3b382901cca64
Autor:
Sravya Kattula, James R. Byrnes, Sara M. Martin, Lori A. Holle, Brian C. Cooley, Matthew J. Flick, Alisa S. Wolberg
Publikováno v:
Blood Advances, Vol 2, Iss 1, Pp 25-35 (2018)
Abstract: The transglutaminase factor XIII (FXIII) stabilizes clots against mechanical and biochemical disruption and is essential for hemostasis. In vitro and in vivo models of venous thrombosis demonstrate that FXIII mediates clot size by promoting
Externí odkaz:
https://doaj.org/article/a8999cfe33124bea952d858ce07e4bff
Autor:
Lisa L Kirkemo, Susanna K Elledge, Jiuling Yang, James R Byrnes, Jeff E Glasgow, Robert Blelloch, James A Wells
Publikováno v:
eLife, Vol 11 (2022)
Characterization of cell surface proteome differences between cancer and healthy cells is a valuable approach for the identification of novel diagnostic and therapeutic targets. However, selective sampling of surface proteins for proteomics requires
Externí odkaz:
https://doaj.org/article/2788c63fd6b14a199fa51148956ffdd4
Autor:
Katarina Pance, Josef A. Gramespacher, James R. Byrnes, Fernando Salangsang, Juan-Antonio C. Serrano, Adam D. Cotton, Veronica Steri, James A. Wells
Publikováno v:
Nature biotechnology, vol 41, iss 2
Targeted degradation of cell surface and extracellular proteins via lysosomal delivery is an important means to modulate extracellular biology. However, these approaches have limitations due to lack of modularity, ease of development, restricted tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad926195dc4d40864e8bef242196e01
https://escholarship.org/uc/item/1bd0b1dm
https://escholarship.org/uc/item/1bd0b1dm
Autor:
Kaitlin Schaefer, Irene Lui, James R. Byrnes, Emily Kang, Jie Zhou, Amy M. Weeks, James A. Wells
Publikováno v:
ACS central science, vol 8, iss 10
Proteolytic cleavage of cell surface proteins triggers critical processes including cell-cell interactions, receptor activation, and shedding of signaling proteins. Consequently, dysregulated extracellular proteases contribute to malignant cell pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e89143c3ebbc4b8a1b5f85ed10d3758
https://pubmed.ncbi.nlm.nih.gov/36313159
https://pubmed.ncbi.nlm.nih.gov/36313159
Autor:
Katarina, Pance, Josef A, Gramespacher, James R, Byrnes, Fernando, Salangsang, Juan-Antonio C, Serrano, Adam D, Cotton, Veronica, Steri, James A, Wells
Publikováno v:
Nature biotechnology.
Targeted degradation of cell surface and extracellular proteins via lysosomal delivery is an important means to modulate extracellular biology. However, these approaches have limitations due to lack of modularity, ease of development, restricted tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::facb0b0deaa4c8f7948bdff8edaa02bb
https://pubmed.ncbi.nlm.nih.gov/36138170
https://pubmed.ncbi.nlm.nih.gov/36138170
Autor:
Susanna K Elledge, Lisa L Kirkemo, Jiuling Yang, James R Byrnes, Jeff E Glasgow, Robert Blelloch, James A Wells
Publikováno v:
eLife. 11
Characterization of cell surface proteome differences between cancer and healthy cells is a valuable approach for the identification of novel diagnostic and therapeutic targets. However, selective sampling of surface proteins for proteomics requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec560a921f8909612d0d723cc690435b
https://doi.org/10.7554/elife.73982
https://doi.org/10.7554/elife.73982
Autor:
Lori A. Holle, Adam Miszta, Asmita Pant, Kirk C. Hansen, Daniel A. Lawrence, Anna K. Kopec, Alisa S. Wolberg, James R. Byrnes, Bas de Laat, James P. Luyendyk, Matthew J. Flick
Publikováno v:
Blood, 135(19), 1704-1717. The American Society of Hematology
Blood
Blood
Obesity is a prevalent prothrombotic risk factor marked by enhanced fibrin formation and suppressed fibrinolysis. Fibrin both promotes thrombotic events and drives obesity pathophysiology, but a lack of essential analytical tools has left fibrinolyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc41635d6f47ad0b66efa99621ba534
https://doi.org/10.1182/blood.2019004267
https://doi.org/10.1182/blood.2019004267