Zobrazeno 1 - 10
of 29
pro vyhledávání: '"James R. Boot"'
Autor:
Claire Vinel, Gabriel Rosser, Loredana Guglielmi, Myrianni Constantinou, Nicola Pomella, Xinyu Zhang, James R. Boot, Tania A. Jones, Thomas O. Millner, Anaelle A. Dumas, Vardhman Rakyan, Jeremy Rees, Jamie L. Thompson, Juho Vuononvirta, Suchita Nadkarni, Tedani El Assan, Natasha Aley, Yung-Yao Lin, Pentao Liu, Sven Nelander, Denise Sheer, Catherine L. R. Merry, Federica Marelli-Berg, Sebastian Brandner, Silvia Marino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The identification of patient-specific disease mechanisms and druggable targets is crucial for precision medicine in glioblastoma. Here, the authors show that comparing patients-matched glioma-initiating cells with neural stem cells enables the disco
Externí odkaz:
https://doaj.org/article/eef727b592d24a7697303fa96e18e608
Autor:
James R. Boot, Denise Sheer, Vardhman K. Rakyan, Catherine L.R. Merry, Claire Vinel, Sebastian Brandner, Sven Nelander, Yung-Yao Lin, Suchita Nadkarni, Tedani El Assan, Juho Vuononvirta, Thomas O Millner, Federica M. Marelli-Berg, Myrianni Constantinou, Loredana Guglielmi, Jamie L. Thompson, Xinyu Zhang, Gabriel Rosser, Tania A. Jones, Pentao Liu, Nicola Pomella, Anaelle A. Dumas, Jeremy Rees, Natasha Aley, Silvia Marino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications
Nature Communications
Epigenetic mechanisms which play an essential role in normal developmental processes, such as self-renewal and fate specification of neural stem cells (NSC) are also responsible for some of the changes in the glioblastoma (GBM) genome. Here we develo
Autor:
James R Boot, Gabriel Rosser, Daliya Kancheva, Claire Vinel, Yau Mun Lim, Nicola Pomella, Xinyu Zhang, Loredana Guglielmi, Denise Sheer, Michael R. Barnes, Sebastian Brandner, Sven Nelander, Kiavash Movahedi, Silvia Marino
We describe a new molecular subgroup of glioblastoma, the most prevalent malignant adult brain tumour, harbouring a bias towards hypomethylation at defined differentially methylated regions. This epigenetic signature correlates with an enrichment for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::479777cb9c250c9de7b5958bbefd73e3
https://doi.org/10.1101/2022.02.15.480525
https://doi.org/10.1101/2022.02.15.480525
Autor:
Xin Sun, Rebecca A. Marks, Rachel L. Eggleston, Kehui Zhang, Chi-Lin Yu, Nia Nickerson, Valeria Caruso, Tai-Li Chou, Xiao-Su Hu, Twila Tardif, James R. Booth, Adriene M. Beltz, Ioulia Kovelman
Publikováno v:
Neurobiology of Language, Vol 4, Iss 2, Pp 198-220 (2023)
AbstractDiversity and variation in language experiences, such as bilingualism, contribute to heterogeneity in children’s neural organization for language and brain development. To uncover sources of such heterogeneity in children’s neural languag
Externí odkaz:
https://doaj.org/article/53eb1a1167d545f49f08a7428b24e1cf
Publikováno v:
Neurobiology of Language, Vol 4, Iss 2, Pp 297-317 (2023)
AbstractOne of the core features of brain maturation is functional specialization. Previous research has found that 7- to 8-year-old children start to specialize in both the temporal and frontal lobes. However, as children continue to develop their p
Externí odkaz:
https://doaj.org/article/6e40e7b184274343bd486dbc151c5a20
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-13 (2022)
Measurement(s) brain activity measurement • behavior or behavioral disorder measurement • Institutional Review Board Independent Ethics Committee Subject Questionnaire • brain structure Technology Type(s) functional magnetic resonance imaging
Externí odkaz:
https://doaj.org/article/8533000f92f84aba8f2d80f35e11a5a4
Autor:
Neelima Wagley, James R. Booth
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Behavioral research shows that children’s phonological ability is strongly associated with better word reading skills, whereas semantic knowledge is strongly related to better reading comprehension. However, most neuroscience research has investiga
Externí odkaz:
https://doaj.org/article/8a2d4eec577f46da85ab92965d08d440
Autor:
Neelima Wagley, James R. Booth
Publikováno v:
NeuroImage, Vol 241, Iss , Pp 118416- (2021)
The present study examined the longitudinal relations of brain and behavior from ages 6–7.5 years old to test the bootstrapping account of language development. Prior work suggests that children's vocabulary development is foundational for acquirin
Externí odkaz:
https://doaj.org/article/33f658de83774df987512687edd3d6b7
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
According to the Interactive Specialization Theory, cognitive skill development is facilitated by a process of neural specialization. In line with this theory, the current study investigated whether neural specialization for phonological and semantic
Externí odkaz:
https://doaj.org/article/c04d869a4ca2474c9294b330a722646b
Publikováno v:
NeuroImage, Vol 236, Iss , Pp 118083- (2021)
By using a longitudinal design and functional magnetic resonance imaging (fMRI), our previous study (Wang et al., 2020) found a scaffolding effect of early phonological processing in the superior temporal gyrus (STG) in 6-year-old children on later b
Externí odkaz:
https://doaj.org/article/613181799c4a4b199225a6d42564cb4c