Zobrazeno 1 - 10
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pro vyhledávání: '"James R. Blackburn"'
Autor:
James R. Blackburn, Ruth Spencer
Publikováno v:
Anaesthesia & Intensive Care Medicine. 13:613-616
Postoperative nausea and vomiting (PONV) remains a common clinical problem that increases patient morbidity, healthcare costs and affects patient satisfaction. This article outlines the physiology, reviews the available drugs and suggests a structure
Publikováno v:
Psychology of Addictive Behaviors. 19:94-98
The authors examined heart rate responses to video lottery terminal (VLT) play and alcohol intake. Forty-four VLT players were randomized to an alcohol (mean blood alcohol concentration=0.06%) or a control beverage condition. Heart rate was recorded
Publikováno v:
Journal of Gambling Studies. 17:297-320
The present study was conducted to identify game parameters that would reduce the risk of abuse of video lottery terminals (VLTs) by pathological gamblers, while exerting minimal effects on the behavior of non-pathological gamblers. Three manipulatio
Publikováno v:
Behavioural Brain Research. 89:99-106
The neural basis of ibogaine's effects on drug-related behaviours is unclear. One possibility is that ibogaine interferes with the shared capacity of many addictive agents to stimulate brain dopamine activity, but reports of ibogaine effects on dopam
Publikováno v:
Life Sciences. 56:2239-2245
It is well-established that dopamine facilitates motor responsiveness. However, neuroleptics — drugs that block dopaminergic transmission — do not affect equally motor responses to environmental stimuli: responses to some stimuli seem completely
Publikováno v:
Progress in Neurobiology. 39:247-279
The data reviewed here are compatible with the hypothesis that telencephalic dopamine activity is elicited by motivationally significant stimuli which in turn creates a neural state in which animals are more prepared to respond to significant stimuli
Publikováno v:
Addictive behaviors. 27(5)
Thirty regular video lottery terminal (VLT) players were randomly assigned to 90 min of VLT play or a control activity (viewing a movie) to examine the impact of VLT play on alcohol use. Ratings of dysphoric mood were taken at baseline, midactivity,
Publikováno v:
Behavioural brain research. 80(1-2)
Three experiments investigated the effects of d-amphetamine on the performance of rats on tasks that required the discrimination of configural cues (i.e., those in which two stimulus elements, tone and light, have a meaning when presented together th
Autor:
W. Jake Jacobs, James R. Blackburn
Publikováno v:
Integrative physiological and behavioral science : the official journal of the Pavlovian Society. 30(1)
We present a model of Pavlovian excitatory conditioning in which associative strength and malleable central representations of unconditional stimuli determine the strength of conditional responding. Presentation of a conditioned stimulus acts through
Publikováno v:
Pharmacology, biochemistry, and behavior. 35(3)
Administration of the neuroleptic drug metoclopramide (5.0 mg/kg) potentiated freezing responses of rats following 1.0 mA footshock, but did not produce any freezing prior to shock onset. To determine if inappropriate freezing responses to shock coul