Zobrazeno 1 - 10
of 19
pro vyhledávání: '"James R. Bayrer"'
Autor:
Candice B. Herber, William C. Krause, Liping Wang, James R. Bayrer, Alfred Li, Matthew Schmitz, Aaron Fields, Breanna Ford, Zhi Zhang, Michelle S. Reid, Daniel K. Nomura, Robert A. Nissenson, Stephanie M. Correa, Holly A. Ingraham
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Estrogen promotes negative energy balance and preserves skeletal physiology. Here the authors show that loss of estrogen signalling after ablating estrogen receptor alpha (ERa) in specific hypothalamic neuronal populations leads to a marked sex-depen
Externí odkaz:
https://doaj.org/article/e716ce14ed5d4a069d7f3a182f6e641a
Autor:
James R. Bayrer, Hongtao Wang, Roy Nattiv, Miyuki Suzawa, Hazel S. Escusa, Robert J. Fletterick, Ophir D. Klein, David D. Moore, Holly A. Ingraham
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Inflammatory bowel disease is characterised by epithelial dysfunction. Here the authors show that loss of the nuclear receptor LRH-1 leads to epithelial disruption by altering Notch signaling in mouse intestinal organoids, and that LRH-1 overexpressi
Externí odkaz:
https://doaj.org/article/90369e6a41a144aa93dc643e36748685
Autor:
James R. Bayrer, Joel Castro, Archana Venkataraman, Kouki K. Touhara, Nathan D. Rossen, Ryan D. Morrie, Jessica Maddern, Aenea Hendry, Kristina N. Braverman, Sonia Garcia-Caraballo, Gudrun Schober, Mariana Brizuela, Fernanda M. Castro Navarro, Carla Bueno-Silva, Holly A. Ingraham, Stuart M. Brierley, David Julius
Publikováno v:
Nature. 616:137-142
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c59a7b1b338d52649ed00b16b6cb4a0
https://doi.org/10.1038/s41586-023-05829-8
https://doi.org/10.1038/s41586-023-05829-8
Autor:
James R. Bayrer, Joel Castro, Archana Venkataraman, Kouki K. Touhara, Nathan D. Rossen, Ryan D. Morrie, Aenea Hendry, Jessica Madden, Kristina N. Braverman, Gudrun Schober, Mariana Brizuela, Carla Bueno Silva, Holly A. Ingraham, Stuart M. Brierley, David Julius
Gastrointestinal (GI) discomfort is a hallmark of most gut disorders and represents a significant component of chronic visceral pain 1. For the growing population afflicted by irritable bowel syndrome (IBS), GI hypersensitivity and pain persist long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1af396c284bbc0d7bd3e392b9ba290d
https://doi.org/10.1101/2022.04.04.486775
https://doi.org/10.1101/2022.04.04.486775
Autor:
Christopher Bowman, Kristina N. Braverman, Kirthana Ganeshan, Yuan Tian, James R. Bayrer, Kevin Man, Peter J. Turnbaugh, Jordan E. Bisanz, Andrew D. Patterson, Ajay Chawla, Veronica Escalante, Biao Wang
Publikováno v:
Proc Natl Acad Sci U S A
Significance Disease tolerance is a host defense strategy that protects tissues from damage caused by pathogens or the immune system. While the importance of disease tolerance is well established in pathogenic infections, its role in tissue protectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a3f93cdbd67ac530b9b3cf85e7cfe6
https://doi.org/10.1073/pnas.2012003117
https://doi.org/10.1073/pnas.2012003117
Autor:
Zhi Zhang, Daniel K. Nomura, Breanna Ford, Michelle S. Reid, James R. Bayrer, Matthew T. Schmitz, Candice B. Herber, William C. Krause, Liping Wang, Alfred Li, Aaron J. Fields, Robert A. Nissenson, Holly A. Ingraham, Stephanie M. Correa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications, vol 10, iss 1
Nature Communications
Nature Communications, vol 10, iss 1
Central estrogen signaling coordinates energy expenditure, reproduction, and in concert with peripheral estrogen impacts skeletal homeostasis in females. Here, we ablate estrogen receptor alpha (ERα) in the medial basal hypothalamus and find a robus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326d67b696241986041037d1cb8e217a
https://doaj.org/article/e716ce14ed5d4a069d7f3a182f6e641a
https://doaj.org/article/e716ce14ed5d4a069d7f3a182f6e641a
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 38, iss 44
The enteric nervous system (ENS) is a large, complex division of the peripheral nervous system that regulates many digestive, immune, hormonal, and metabolic functions. Recent advances have elucidated the dynamic nature of the mature ENS, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09274ac91f603c5e65e35ded2d895d9
https://doi.org/10.1523/jneurosci.1663-18.2018
https://doi.org/10.1523/jneurosci.1663-18.2018
Autor:
Thomas E Wallach, James R. Bayrer
Publikováno v:
Journal of pediatric gastroenterology and nutrition, vol 64, iss 2
The development of sustainable intestinal organoid cell culture has emerged as a new modality for the study of intestinal function and cellular processes. Organoid culture is providing a new test-bed for therapeutic research and development. Intestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7f41fffab5d0f141e69ce069437c05
https://doi.org/10.1097/mpg.0000000000001411
https://doi.org/10.1097/mpg.0000000000001411
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8cdbb2c551408e989dd6a483a2df633
https://doi.org/10.1096/fasebj.2020.34.s1.06185
https://doi.org/10.1096/fasebj.2020.34.s1.06185
Autor:
Miyuki Suzawa, James R. Bayrer, Ophir D. Klein, Hazel S. Escusa, David D. Moore, Holly A. Ingraham, Robert J. Fletterick, Roy Nattiv, Hongtao Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature communications, vol 9, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature communications, vol 9, iss 1
Epithelial dysfunction and crypt destruction are defining features of inflammatory bowel disease (IBD). However, current IBD therapies targeting epithelial dysfunction are lacking. The nuclear receptor LRH-1 (NR5A2) is expressed in intestinal epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf6383aed846629510385eb9942ea7e
https://pubmed.ncbi.nlm.nih.gov/30305617
https://pubmed.ncbi.nlm.nih.gov/30305617