Zobrazeno 1 - 10
of 30
pro vyhledávání: '"James R. A. Hutchins"'
Autor:
James R. A. Hutchins, Isabelle Peiffer, Serge Urbach, Jean-Louis Mergny, Philippe Marin, Domenico Maiorano, Marcel Méchali
In metazoan cells, replication of genomic DNA initiates from thousands of discrete chromosomal loci known as origins. Proteins such as the Origin Recognition Complex (ORCs) associate with origins, but this does not show clear sequence specificity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7499f30a00d12459488a640458dd1914
https://doi.org/10.1101/2023.03.30.534946
https://doi.org/10.1101/2023.03.30.534946
Autor:
Maria Novatchkova, Jean-Karim Hériché, Emanuel Kreidl, Jan-Michael Peters, Otto Hudecz, Karl Mechtler, Rene Ladurner, Gordana Wutz, Petra van der Lelij, Evelyn Rampler, Miroslav P Ivanov, Ina Poser, Jan Ellenberg, Anthony A. Hyman, Rebecca Beveridge, James R. A. Hutchins, Heinz Axelsson‐Ekker
Publikováno v:
The EMBO Journal
EMBO Journal
EMBO Journal, EMBO Press, 2018, ⟨10.15252/embj.201797150⟩
EMBO Journal
EMBO Journal, EMBO Press, 2018, ⟨10.15252/embj.201797150⟩
Chromosome segregation depends on sister chromatid cohesion which is established by cohesin during DNA replication. Cohesive cohesin complexes become acetylated to prevent their precocious release by WAPL before cells have reached mitosis. To obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8242abe6180d60333f7c0b2864d5fb80
https://europepmc.org/articles/PMC6068434/
https://europepmc.org/articles/PMC6068434/
Autor:
Daniel Latreille, Magali Kitzmann, Sabine Traver, Philippe Coulombe, Isabelle Peiffer, Marcel Méchali, James R. A. Hutchins
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2015, 59 (5), pp.831-839. ⟨10.1016/j.molcel.2015.07.010⟩
Molecular Cell, Elsevier, 2015, 59 (5), pp.831-839. ⟨10.1016/j.molcel.2015.07.010⟩
International audience; DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects DNA polymerase errors during replication to maintain genomic integrity. In E. coli, the DNA helicase UvrD is implicated in MMR, yet an analogous he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b49395fa5d1dc7b6dde3838d7f9b98
https://doi.org/10.1016/j.molcel.2015.07.010
https://doi.org/10.1016/j.molcel.2015.07.010
Autor:
James R A, Hutchins
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1525
The availability of reference genome sequences for virtually all species under active research has revolutionized biology. Analyses of genomic variations in many organisms have provided insights into phenotypic traits, evolution and disease, and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f40f92ec8be04b6d9ef8b8ad7e51380
https://pubmed.ncbi.nlm.nih.gov/27896724
https://pubmed.ncbi.nlm.nih.gov/27896724
Autor:
James R. A. Hutchins
Publikováno v:
Methods in Molecular Biology
Methods in Molecular Biology, 1525, pp.225-269, 2016, Bioinformatics, 978-1-4939-6620-2
Methods in Molecular Biology ISBN: 9781493966202
Methods in Molecular Biology, 1525, pp.225-269, 2016, Bioinformatics, 978-1-4939-6620-2
Methods in Molecular Biology ISBN: 9781493966202
International audience; The availability of reference genome sequences for virtually all species under active research has revolutionized biology. Analyses of genomic variations in many organisms have provided insights into phenotypic traits, evoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc22e4c1a220e42a0797eb98595c8a15
https://hal.archives-ouvertes.fr/hal-02363544
https://hal.archives-ouvertes.fr/hal-02363544
Autor:
Laurence Pelletier, Anja Nitzsche, Steffen Dietzel, Jan-Michael Peters, Alexander W. Bird, Martina Augsburg, Björn Hegemann, Mihail Sarov, Martina M. Sykora, Ralf Kittler, James R. A. Hutchins, A. Francis Stewart, Yusuke Toyoda, Daniela Weigl, Helmut Hofemeister, Ronald Naumann, Ina Poser, Kim Nasmyth, Kevin P. White, Andrei Pozniakovsky, Anthony A. Hyman, Youming Zhang, Richard Durbin, Sujun Hua, Jean-Karim Hériché, Frank Buchholz, Karl Mechtler
The interpretation of genome sequences requires reliable and standardized methods to assess protein function at high throughput. Here we describe a fast and reliable pipeline to study protein function in mammalian cells based on protein tagging in ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee83959ea392bcd278c3c333bb7981b
https://ora.ox.ac.uk/objects/uuid:19433e36-e5b5-4a80-9d4e-d0b912701619
https://ora.ox.ac.uk/objects/uuid:19433e36-e5b5-4a80-9d4e-d0b912701619
Publikováno v:
DNA Replication, Recombination, and Repair ISBN: 9784431558712
DNA replication in metazoan cells initiates at multiple discrete chromosomal sites called replication origins. Recent genome-wide studies have mapped thousands of origins in animal and plant cells, but without yielding a distinct and universal consen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1ab9215648d6d48d5f7ee1cb91b9416
https://doi.org/10.1007/978-4-431-55873-6_2
https://doi.org/10.1007/978-4-431-55873-6_2
Autor:
Otto Hudecz, Anthony A. Hyman, Jan-Michael Peters, Daniel W. Gerlich, Karl Mechtler, Veerle Janssens, Michael H.A. Schmitz, Jozef Goris, James R. A. Hutchins, Ina Poser, Laura Trinkle-Mulcahy, Elitsa Ivanova, Angus I. Lamond, Michael Held
Publikováno v:
Nature Cell Biology. 12:886-893
When vertebrate cells exit mitosis various cellular structures are re-organized to build functional interphase cells. This depends on Cdk1 (cyclin dependent kinase 1) inactivation and subsequent dephosphorylation of its substrates. Members of the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1675fb298e4ae7b8de309d2d3b437360
https://doi.org/10.1038/ncb2092
https://doi.org/10.1038/ncb2092
Autor:
Jutta Bulkescher, James R. A. Hutchins, Frank Buchholz, Steffen Lawo, Kim Nasmyth, Jan Ellenberg, Siegfried Schloissnig, Holger Stark, Björn Hegemann, Martina M. Sykora, Christian Conrad, Ines Steinmacher, Ina Poser, Richard Durbin, Mihail Sarov, Otto Hudecz, Martina Augsburg, Bettina A. Buschhorn, David Comartin, Mikolaj Slabicki, Jean-Karim Hériché, Andrei Pozniakovsky, Anthony A. Hyman, Laurence Pelletier, Jan-Michael Peters, Andrea Ssykor, Yusuke Toyoda, Karl Mechtler, Marit Leuschner, Alexander Schleiffer
Publikováno v:
Science
Division Machinery Tagged An international consortium of labs has been testing the feasibility of large-scale screening for insights into the function of mammalian proteins by expressing a tagged version of proteins from bacterial artificial chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39dbcb0b7e3a967aa1f40e652110bee1
https://doi.org/10.1126/science.1181348
https://doi.org/10.1126/science.1181348
Autor:
Goran Mitulović, James R. A. Hutchins, Jan-Michael Peters, Karl Mechtler, Ines Steinmacher, Otto Hudecz, Christoph Stingl
Publikováno v:
Analytical Chemistry. 81:5955-5960
Sample carryover is a significant problem that occurs in high-performance liquid chromatography (HPLC) analysis. Carryover effects cannot be tolerated in any high-performance liquid chromatography-mass spectroscopy (HPLC-MS) separation system, and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439dbd558f6d692f8d5d04daa7476cb2
https://doi.org/10.1021/ac900696m
https://doi.org/10.1021/ac900696m