Zobrazeno 1 - 10
of 17
pro vyhledávání: '"James R Rybarski"'
Autor:
R A Greenstein, Stephen K Jones, Eric C Spivey, James R Rybarski, Ilya J Finkelstein, Bassem Al-Sady
Publikováno v:
eLife, Vol 7 (2018)
The heterochromatin spreading reaction is a central contributor to the formation of gene-repressive structures, which are re-established with high positional precision, or fidelity, following replication. How the spreading reaction contributes to thi
Externí odkaz:
https://doaj.org/article/9d32e1b6a87f4b8290f280e7b3b65dd7
Publikováno v:
eLife, Vol 6 (2017)
The replicative lifespan (RLS) of a cell—defined as the number of cell divisions before death—has informed our understanding of the mechanisms of cellular aging. However, little is known about aging and longevity in symmetrically dividing eukaryo
Externí odkaz:
https://doaj.org/article/a7eeb65a76214b0ba05ffc0a0758032a
Autor:
Yu‐An Kuo, Cheulhee Jung, Yu‐An Chen, Hung‐Che Kuo, Oliver S. Zhao, Trung D. Nguyen, James R. Rybarski, Soonwoo Hong, Yuan‐I Chen, Dennis C. Wylie, John A. Hawkins, Jada N. Walker, Samuel W. J. Shields, Jennifer S. Brodbelt, Jeffrey T. Petty, Ilya J. Finkelstein, Hsin‐Chih Yeh
NanoCluster Beacons (NCBs) are multicolor silver nanocluster probes whose fluorescence can be activated or tuned by a proximal DNA strand called the activator. While a single-nucleotide difference in a pair of activators can lead to drastically diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807e302043c7c4a15261ec93940a523c
https://doi.org/10.1101/2021.12.04.471212
https://doi.org/10.1101/2021.12.04.471212
Autor:
Yu‐An Kuo, Cheulhee Jung, Yu‐An Chen, Hung‐Che Kuo, Oliver S. Zhao, Trung D. Nguyen, James R. Rybarski, Soonwoo Hong, Yuan‐I Chen, Dennis C. Wylie, John A. Hawkins, Jada N. Walker, Samuel W. J. Shields, Jennifer S. Brodbelt, Jeffrey T. Petty, Ilya J. Finkelstein, Hsin‐Chih Yeh
Publikováno v:
Advanced Materials. 34:2270286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e024459c8e1bdba12785b33f65aa70
https://doi.org/10.1002/adma.202270286
https://doi.org/10.1002/adma.202270286
Publikováno v:
Proc Natl Acad Sci U S A
CRISPR-associated transposons (CASTs) co-opt Cas genes for RNA-guided transposition. CASTs are exceedingly rare in genomic databases; recent surveys have reported Tn7-like transposons that co-opt Type I-F, I-B, and V-K CRISPR effectors. Here, we expa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2575d1d3ea1570566f5444c3edfb60
https://doi.org/10.1101/2021.08.16.456562
https://doi.org/10.1101/2021.08.16.456562
Autor:
Stephen K. Jones, John A. Hawkins, Jennifer A. Doudna, James R. Rybarski, Ilya J. Finkelstein, William H. Press, Janice S. Chen, Nicole V. Johnson, Cheulhee Jung, Kuang Hu
Publikováno v:
Nat Biotechnol
Engineered Streptococcus pyogenes (Sp) Cas9s and Acidaminococcus sp. (As) Cas12a (formerly Cpf1) improve cleavage specificity in human cells. However, the fidelity, enzymatic mechanisms, and cleavage products of emerging CRISPR nucleases have not bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311cb02e8cb8901ed1766f35be805608
https://europepmc.org/articles/PMC9665413/
https://europepmc.org/articles/PMC9665413/
Publikováno v:
Journal of Open Source Software. 6:3678
Gene clusters are sets of co-localized, often contiguous genes that together perform specific functions, many of which are relevant to biotechnology. There is a need for software tools that can extract candidate gene clusters from vast amounts of ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef1fcd885a5a9b7d910c31ebcbd729c
https://doi.org/10.21105/joss.03678
https://doi.org/10.21105/joss.03678
Autor:
Yin An Chen, Hsin-Chih Yeh, Hung-Che Kuo, Yuan-I. Chen, Oliver S. Zhao, Victor A. Madrid, Trung D. Nguyen, Ilya J. Finkelstein, Yu-An Kuo, Yu An Chen, James R. Rybarski, Yen-Liang Liu, Jeffrey T. Petty, Cheulhee Jung, John A. Hawkins
Publikováno v:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XI.
Invented in 2010, NanoCluster Beacons (NCBs) (1) are an emerging class of turn-on probes that show unprecedented capabilities in single-nucleotide polymorphism (2) and DNA methylation (3) detection. As the activation colors of NCBs can be tuned by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112fcce1e7ed154f521bd872a1664cf3
https://doi.org/10.1117/12.2510649
https://doi.org/10.1117/12.2510649
Autor:
Tim Yeh, Yu-An Kuo, Trung D. Nguyen, Yen-Liang Liu, Soonwoo Hong, Ilya J. Finkelstein, Yuan-I. Chen, Hung-Che Kuo, James R. Rybarski, Oliver S. Zhao
Publikováno v:
Biophysical Journal. 118:624a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a119d3a4d2eed5e3ea8aa1a0ba121cb
https://doi.org/10.1016/j.bpj.2019.11.3362
https://doi.org/10.1016/j.bpj.2019.11.3362
Autor:
Stephen K. Jones, Ilya J. Finkelstein, R A Greenstein, Eric C. Spivey, Bassem Al-Sady, James R. Rybarski
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
The heterochromatin spreading reaction is a central contributor to the formation of gene-repressive structures, which are re-established with high positional precision, or fidelity, following replication. How the spreading reaction contributes to thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b7edcc76e712a4b18bc78f334ccc69
https://doi.org/10.7554/elife.32948
https://doi.org/10.7554/elife.32948