Zobrazeno 1 - 10
of 98
pro vyhledávání: '"James R Perkins"'
Autor:
Elena Díaz-Santiago, Fernando M Jabato, Elena Rojano, Pedro Seoane, Florencio Pazos, James R Perkins, Juan A G Ranea
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009054 (2020)
Genetic and molecular analysis of rare disease is made difficult by the small numbers of affected patients. Phenotypic comorbidity analysis can help rectify this by combining information from individuals with similar phenotypes and looking for overla
Externí odkaz:
https://doaj.org/article/6dd3ee164edf4928a8b351983cede7ae
Autor:
John M Dawes, Ana Antunes-Martins, James R Perkins, Kathryn J Paterson, Marco Sisignano, Ramona Schmid, Werner Rust, Tobias Hildebrandt, Gerd Geisslinger, Christine Orengo, David L Bennett, Stephen B McMahon
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93338 (2014)
Ultraviolet-B (UVB)-induced inflammation produces a dose-dependent mechanical and thermal hyperalgesia in both humans and rats, most likely via inflammatory mediators acting at the site of injury. Previous work has shown that the gene expression of c
Externí odkaz:
https://doaj.org/article/7a5327c1699a45d0aadd2fdc1a6d0f0e
Autor:
Antonio, Vega-Rioja, Pedro, Chacón, Lourdes, Fernández-Delgado, Bouchra, Doukkali, Alberto, Del Valle Rodríguez, James R, Perkins, Juan A G, Ranea, Leticia, Dominguez-Cereijo, Beatriz María, Pérez-Machuca, Ricardo, Palacios, David, Rodríguez, Javier, Monteseirín, David, Ribas-Pérez
BackgroundNeutrophils are involved in the pathophysiology of allergic asthma, where the Eosinophil Cationic Protein(ECP) is a critical inflammatory mediator. Although ECP production is attributed to eosinophils, we reported that ECP is also present i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4085b51f2fa85c82fd717a4d7af9ad42
Autor:
James R Perkins, R Srikant
Publikováno v:
Systems modelling and optimization ISBN: 9780203737422
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da0026e5a2e65c090c7ccad7255eb364
https://doi.org/10.1201/9780203737422-36
https://doi.org/10.1201/9780203737422-36
Autor:
Fernando M. Jabato, Florencio Pazos, Elena Rojano, Juan A. G. Ranea, James R. Perkins, Pedro Seoane, Adrián García Moreno, Monica Chagoyen
Publikováno v:
Human Genetics. 140:457-475
Copy number variation (CNV) related disorders tend to show complex phenotypic profiles that do not match known diseases. This makes it difficult to ascertain their underlying molecular basis. A potential solution is to compare the affected genomic re
Autor:
Carlos Romá-Mateo, James R. Perkins, Pedro Seoane, Belén Pérez, Juan A. G. Ranea, Elena Rojano, Diana Gallego, José Córdoba-Caballero, Fernando M. Jabato, Pascual Sanz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
instname
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
12 páginas, 7 figuras, 2 tablas. Te online version contains supplementary material available at https://doi.org/ 10.1038/s41598-021-94343-w . Code is available at the bioconductor landing page https://bioconductor.org/packages/ExpHunterSuite. Te lat
Autor:
A García-Sánchez, Rosa Muñoz-Cano, Pedro Ayuso, Raquel Jurado-Escobar, Jose Julio Laguna, Inmaculada Doña, M.J. Torres, Cristobalina Mayorga, Jose A. Cornejo-Garcia, James R. Perkins
Publikováno v:
The British journal of dermatologyReferences. 185(4)
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are the main triggers of drug hypersensitivity, with NSAID-induced acute urticaria/angioedema (NIUA) the most frequent phenotype. NSAID hypersensitivity is caused by cyclooxygenase 1 inhibition
Autor:
Raquel Jurado-Escobar, Inmaculada Doña, José Triano-Cornejo, James R. Perkins, Natalia Pérez-Sánchez, Almudena Testera-Montes, Marina Labella, Joan Bartra, José J. Laguna, Miguel Estravís, José A. G. Agúndez, María J. Torres, José A. Cornejo-García
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the main triggers of drug hypersensitivity reactions, probably due to their high consumption worldwide. The most frequent type of NSAID hypersensitivity is NSAID cross-hypersensitivity, in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c8555b31e972a4c97d8baad7d015a0
https://hdl.handle.net/10668/3525
https://hdl.handle.net/10668/3525
Autor:
Elena Díaz-Santiago, M. Gonzalo Claros, Raquel Yahyaoui, Yolanda de Diego-Otero, Rocío Calvo, Janet Hoenicka, Francesc Palau, Juan A. G. Ranea, James R. Perkins
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Neuromuscular disorders (NMDs) represent an important subset of rare diseases associated with elevated morbidity and mortality whose diagnosis can take years. Here we present a novel approach using systems biology to produce functionally-coherent phe
Autor:
James R. Perkins, Pedro Seoane, José Córdoba-Caballero, Manuel Manchado, M. Gonzalo Claros, Fernando M. Jabato
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Senegalese sole is an economically important flatfish species in aquaculture and an attractive model to decipher the molecular mechanisms governing the severe transformations occurring during metamorphosis, where retinoic acid seems to play a key rol