Zobrazeno 1 - 10
of 54
pro vyhledávání: '"James R Lambert"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303470 (2024)
VDX-111 (also identified as AMPI-109) is a vitamin D derivative which has shown anticancer activity. To further assess the function of this compound against multiple cancer types, we examined the efficacy of VDX-111 against a panel of 30 well charact
Externí odkaz:
https://doaj.org/article/61e188de38e44998a8d4a237e82dff33
Autor:
Wenbo Zhang, Cheng Hu, Xiaojie Wang, Shanshan Bai, Subing Cao, Margaret Kobelski, James R Lambert, Jingkai Gu, Yang Zhan
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222812 (2019)
The growth inhibitory efficacy of methylseleninic acid (MSA) in prostate cancer cells has been documented extensively. However, our understanding of the immediate targets that are key to the growth inhibitory effects of MSA remains limited. Here, usi
Externí odkaz:
https://doaj.org/article/598b9e0bcd294b83b4d336f210a3e723
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Comparison of Gene Signatures following miR-200c Restoration in TNBC Cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e2e34fce6fd246f0255ad336746aaa
https://doi.org/10.1158/1541-7786.22515610.v1
https://doi.org/10.1158/1541-7786.22515610.v1
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Expanded GSEA results following miR-200c restoration in TNBC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555ec23b551357ccd1c7aa389b86c5fc
https://doi.org/10.1158/1541-7786.22515607.v1
https://doi.org/10.1158/1541-7786.22515607.v1
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Extended list of genes associated with enriched immunosuppressive pathways following GSEA analysis in BT549-TripZ-200c cells following miR-200c restoration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405dfbca8852bcbf9a252fd18c173963
https://doi.org/10.1158/1541-7786.22515601.v1
https://doi.org/10.1158/1541-7786.22515601.v1
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Tryptophan-2,3-dioxygenase (TDO2), a rate-limiting enzyme in the tryptophan catabolism pathway, is induced in triple-negative breast cancer (TNBC) by inflammatory signals and anchorage-independent conditions. TNBCs express extremely low levels of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc6d9fbc058d2c98a4835c7d1cbfa59
https://doi.org/10.1158/1541-7786.c.6541138
https://doi.org/10.1158/1541-7786.c.6541138
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Extended list of genes associated with top 10 enriched pathways following GSEA analysis in BT549-TripZ-200c cells following miR-200c restoration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f36be19a322cceb3e4ad35cba637fd6
https://doi.org/10.1158/1541-7786.22515598.v1
https://doi.org/10.1158/1541-7786.22515598.v1
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Effects of TNF-a or IL-1B or the combination on HO-1 protein in BT549 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185bf4fa0ab0059291e0561d89270fae
https://doi.org/10.1158/1541-7786.22515604.v1
https://doi.org/10.1158/1541-7786.22515604.v1
Autor:
James R. Lambert, Steven K. Nordeen
Publikováno v:
AIMS Molecular Science, Vol 2, Iss 2, Pp 64-76 (2015)
Transcriptional induction by steroid receptors is coupled to cellular signal transduction pathways although, in general, the mechanisms governing these events are not well defined. Using TATA-binding protein (TBP) specificity mutants that recognize a
Externí odkaz:
https://doaj.org/article/b0ee07202da442eda2d80f6e0772e819
Autor:
Nabanita Mukherjee, Chiara R. Dart, Carol M. Amato, Adam Honig-Frand, James R. Lambert, Karoline A. Lambert, William A. Robinson, Richard P. Tobin, Martin D. McCarter, Kasey L. Couts, Mayumi Fujita, David A. Norris, Yiqun G. Shellman
Publikováno v:
J Invest Dermatol
Uveal melanoma (UM) is a subtype of melanoma. Although they share a melanocytic origin with cutaneous melanoma (CM), patients with UM have few treatment options. BCL2 homologous 3 mimetics are small-molecule drugs that mimic proapoptotic BCL2 family