Zobrazeno 1 - 2
of 2
pro vyhledávání: '"James R J, Gray"'
Autor:
Lee A, Harrison, Stephen J, Atkinson, Anna, Bassil, Chun-Wa, Chung, Paola, Grandi, James R J, Gray, Etienne, Levernier, Antonia, Lewis, David, Lugo, Cassie, Messenger, Anne-Marie, Michon, Darren J, Mitchell, Alex, Preston, Rab K, Prinjha, Inmaculada, Rioja, Jonathan T, Seal, Simon, Taylor, Ian D, Wall, Robert J, Watson, James M, Woolven, Emmanuel H, Demont
Publikováno v:
Journal of medicinal chemistry. 64(15)
Domain-specific BET bromodomain ligands represent an attractive target for drug discovery with the potential to unlock the therapeutic benefits of antagonizing these proteins without eliciting the toxicological aspects seen with pan-BET inhibitors. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29838ca81add590d8ccf661d7c0b5e04
https://pubmed.ncbi.nlm.nih.gov/34232650
https://pubmed.ncbi.nlm.nih.gov/34232650
Autor:
Alex, Preston, Stephen, Atkinson, Paul, Bamborough, Chun-Wa, Chung, Peter D, Craggs, Laurie, Gordon, Paola, Grandi, James R J, Gray, Emma J, Jones, Matthew, Lindon, Anne-Marie, Michon, Darren J, Mitchell, Rab K, Prinjha, Francesco, Rianjongdee, Inmaculada, Rioja, Jonathan, Seal, Simon, Taylor, Ian, Wall, Robert J, Watson, James, Woolven, Emmanuel H, Demont
Publikováno v:
Journal of medicinal chemistry. 63(17)
Pan-bromodomain and extra terminal domain (BET) inhibitors interact equipotently with the eight bromodomains of the BET family of proteins and have shown profound efficacy in a number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4046d324ecd8b85a10f0784785606a9e
https://pubmed.ncbi.nlm.nih.gov/32691591
https://pubmed.ncbi.nlm.nih.gov/32691591