Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James R F, Hockley"'
Publikováno v:
Frontiers in Communication, Vol 7 (2022)
Chronic gastrointestinal (GI) tract conditions, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are common conditions associated with disordered bowel movements and significant pain. However, discussion of bowel habits is
Externí odkaz:
https://doaj.org/article/4793d2f7a1c24670851e6a7544735cd0
Autor:
Toni S. Taylor, Parvesh Konda, Sarah S. John, David C. Bulmer, James R. F. Hockley, Ewan St. John Smith
Publikováno v:
Physiological Reports, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract Galanin is a neuropeptide expressed by sensory neurones innervating the gastrointestinal (GI) tract. Galanin displays inhibitory effects on vagal afferent signaling within the upper GI tract, and the goal of this study was to determine the a
Externí odkaz:
https://doaj.org/article/43d932d5034d41e1a77ebd1e7b62ce9e
Autor:
Cian, McGuire, George, Boundouki, James R F, Hockley, David, Reed, Vincent, Cibert-Goton, Madusha, Peiris, Victor, Kung, John, Broad, Qasim, Aziz, Christopher, Chan, Shafi, Ahmed, Mohamed A, Thaha, Gareth J, Sanger, L Ashley, Blackshaw, Charles H, Knowles, David C, Bulmer
Publikováno v:
Gut
Objective The development of effective visceral analgesics free of deleterious gut-specific side effects is a priority. We aimed to develop a reproducible methodology to study visceral nociception in human tissue that could aid future target identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::045542405f4253d63dfaefa24868775d
https://pubmed.ncbi.nlm.nih.gov/27654583
https://pubmed.ncbi.nlm.nih.gov/27654583
Autor:
James R F, Hockley, George, Boundouki, Vincent, Cibert-Goton, Cian, McGuire, Ping K, Yip, Christopher, Chan, Michael, Tranter, John N, Wood, Mohammed A, Nassar, L Ashley, Blackshaw, Qasim, Aziz, Gregory J, Michael, Mark D, Baker, Wendy J, Winchester, Charles H, Knowles, David C, Bulmer
Publikováno v:
Pain
Summary NaV1.9 regulates normal colonic afferent mechanosensation and is required for hypersensitivity to noxious inflammatory mediators and those derived from inflammatory bowel disease tissues.
Chronic visceral pain affects millions of individ
Chronic visceral pain affects millions of individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4abfaa40c6512fd616ab31daebc8f625
https://pubmed.ncbi.nlm.nih.gov/24972070
https://pubmed.ncbi.nlm.nih.gov/24972070