Zobrazeno 1 - 10
of 149
pro vyhledávání: '"James R, Swartz"'
Publikováno v:
International Journal of Hydrogen Energy. 45:30201-30210
Hydrogenase intolerance to oxygen remains a critical hurdle on the road to photosynthetic hydrogen production for sustainable energy demands. Although the engineering of the intrinsic oxygen tolerance mechanism of hydrogenase using mutagenesis is an
Autor:
James R. Swartz
Publikováno v:
Current Opinion in Biotechnology. 62:248-255
Hydrogen is already a major commodity and process intermediate for fertilizer production, petroleum processing, and chemical synthesis. It also offers unrealized potential for energy storage. While biological production offers an expandable and susta
Publikováno v:
Molecular Systems Biology, Vol 4, Iss 1, Pp 1-10 (2008)
Abstract Cell‐free systems offer a unique platform for expanding the capabilities of natural biological systems for useful purposes, i.e. synthetic biology. They reduce complexity, remove structural barriers, and do not require the maintenance of c
Externí odkaz:
https://doaj.org/article/e8c405df0a1b48a88d562c599ce54146
Autor:
James F, Zawada, David, Burgenson, Gang, Yin, Trevor J, Hallam, James R, Swartz, Robert D, Kiss
Publikováno v:
Current Opinion in Biotechnology. 76:102719
Cell-free protein synthesis (CFPS) technologies have grown from lab-scale research tools to biopharmaceutical production at the Good Manufacturing Practice manufacturing scale. Multiple human clinical trials are in progress with CFPS-based products.
Autor:
Ranjan Patnaik, James R. Swartz
Publikováno v:
BioTechniques, Vol 24, Iss 5, Pp 862-868 (1998)
A highly efficient Escherichia coli-based, batch in vitro protein synthesis system using circular plasmid DNA is described. Compared to a presently available commercial kit, this improved system produced several hundredfold greater yields of the rDNA
Externí odkaz:
https://doaj.org/article/b3641de04d4c4ae3b0252420f16d6f6e
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45850 (2012)
[FeFe] hydrogenases catalyze H(2) production using the H-cluster, an iron-sulfur cofactor that contains carbon monoxide (CO), cyanide (CN(-)), and a dithiolate bridging ligand. The HydE, HydF, and HydG maturases assist in assembling the H-cluster and
Externí odkaz:
https://doaj.org/article/5787bdae941e48adacf3c85d2d4f8c54
Autor:
Bradley C. Bundy, James R. Swartz, Michael C. Jewett, Govind Rao, J. Porter Hunt, Douglas D. Frey, David W. Wood
Publikováno v:
Current Opinion in Chemical Engineering. 22:177-183
Since its early development and use to decipher the genetic code, in vitro or ‘cell-free’ systems have been used as an important research tool to understand biochemical mechanisms and metabolic pathways. More recently, due to important engineerin
Autor:
James R. Swartz, Julie A Fogarty
Publikováno v:
Current Opinion in Chemical Engineering. 19:1-8
Most current vaccine strategies employ live-attenuated or killed versions of the pathogen. While effective in the developed world, expense and cold-chain dependence make broad access to such vaccines difficult in the developing world. Additionally, c
Autor:
Jon M Kuchenreuther, Simon J George, Celestine S Grady-Smith, Stephen P Cramer, James R Swartz
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20346 (2011)
[FeFe] hydrogenases are promising catalysts for producing hydrogen as a sustainable fuel and chemical feedstock, and they also serve as paradigms for biomimetic hydrogen-evolving compounds. Hydrogen formation is catalyzed by the H-cluster, a unique i
Externí odkaz:
https://doaj.org/article/0748a66356b24d1790c7fd7ed1a95fc1
Autor:
James A Stapleton, James R Swartz
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10554 (2010)
Background[FeFe] hydrogenase enzymes catalyze the production and dissociation of H(2), a potential renewable fuel. Attempts to exploit these catalysts in engineered systems have been hindered by the biotechnologically inconvenient properties of the n
Externí odkaz:
https://doaj.org/article/21ee64d798ee42d3a1366daff9215b25