Zobrazeno 1 - 10
of 195
pro vyhledávání: '"James R, O'Dell"'
Autor:
Concepcion Sanchez, Anaamika Campeau, Ru Liu-Bryan, Ted R. Mikuls, James R. O’Dell, David J. Gonzalez, Robert Terkeltaub
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Urate-lowering treatment (ULT) to target with xanthine oxidase inhibitors (XOIs) paradoxically causes early increase in gouty arthritis flares. Because delayed reduction in flare burden is mechanistically unclear, we tested for ULT inflammat
Externí odkaz:
https://doaj.org/article/e349f9cade8a437bae5fe3b49312ee3e
Autor:
Lauren A. Vanderlinden, Elizabeth A. Bemis, Jennifer Seifert, Joel M. Guthridge, Kendra A. Young, Mary Kristen Demoruelle, Marie Feser, Wade DeJager, Susan Macwana, Ted R. Mikuls, James R. O’Dell, Michael H. Weisman, Jane Buckner, Richard M. Keating, Patrick M. Gaffney, Jennifer A. Kelly, Carl D. Langefeld, Kevin D. Deane, Judith A. James, Vernon Michael Holers, Jill M. Norris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveHigher 25-hydroxyvitamin D (25(OH)D) levels have been associated with reduced risk for autoimmune diseases and are influenced by vitamin D metabolism genes. We estimated genetically-determined vitamin D levels by calculating a genetic risk s
Externí odkaz:
https://doaj.org/article/8ead74bae78b4210a2dbb92be12d3596
Autor:
Yun-Jeong Song, In Ah. Choi, Françoise Meylan, M. Kristen Demoruelle, Taylor Farley, Arianne C. Richard, Eric Hawley, John Botson, Yoo Jin Hong, Eun Young Lee, Sabina R. Mian, Bartlett C. Hamilton, Geoffrey M. Thiele, Ted R. Mikuls, Naveen Gara, Chris D. Ward, Sarah Lamberth, Kevin D. Deane, Theo Heller, Michael M. Ward, David M. Lee, Thi-Sau Migone, William Stohl, James R. O’Dell, Jill M. Norris, V. Michael Holers, Peter Gregersen, Yeong-Wook Song, Richard M. Siegel
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background The tumor necrosis factor (TNF) superfamily cytokine TNF-like protein 1A (TL1A) and its receptor DR3 are essential for diverse animal models of autoimmune disease and may be pathogenic in rheumatoid arthritis (RA). However, the re
Externí odkaz:
https://doaj.org/article/67eda1b4a8ed453b9815ed1b537021d9
Autor:
Cory J. Rohlfsen, Harlan Sayles, Gerald F. Moore, Ted R. Mikuls, James R. O’Dell, Sarah McBrien, Tate Johnson, Zachary D. Fowler, Amy C. Cannella
Publikováno v:
BMC Medical Education, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Despite a paucity of evidence to support a multitude of educational innovations, curricular leaders are pressured to find innovative solutions to better prepare medical students for an evolving twenty-first century health care sys
Externí odkaz:
https://doaj.org/article/8a74054b80424c4992929ebe05b82a6f
Autor:
Judith A. James, Hua Chen, Kendra A. Young, Elizabeth A. Bemis, Jennifer Seifert, Rebecka L. Bourn, Kevin D. Deane, M. Kristen Demoruelle, Marie Feser, James R. O'Dell, Michael H. Weisman, Richard M. Keating, Patrick M. Gaffney, Jennifer A. Kelly, Carl D. Langefeld, John B. Harley, William Robinson, David A. Hafler, Kevin C. O'Connor, Jane Buckner, Joel M. Guthridge, Jill M. Norris, V. Michael Holers
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 76-85 (2019)
Background: Autoimmune disease prevention requires tools to assess an individual's risk of developing a specific disease. One tool is disease-associated autoantibodies, which accumulate in an asymptomatic preclinical period. However, patients sometim
Externí odkaz:
https://doaj.org/article/29eb22cbe4fa4d878a3a2e72c9e266ed
Autor:
Jason Ptacek, Rachael E Hawtin, Dongmei Sun, Brent Louie, Erik Evensen, Barbara B Mittleman, Alessandra Cesano, Guy Cavet, Clifton O Bingham, Stacey S Cofield, Jeffrey R Curtis, Maria I Danila, Chander Raman, Richard A Furie, Mark C Genovese, William H Robinson, Marc C Levesque, Larry W Moreland, Peter A Nigrovic, Nancy A Shadick, James R O'Dell, Geoffrey M Thiele, E William St Clair, Christopher C Striebich, Matthew B Hale, Houman Khalili, Franak Batliwalla, Cynthia Aranow, Meggan Mackay, Betty Diamond, Garry P Nolan, Peter K Gregersen, S Louis Bridges
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244187 (2021)
Rheumatoid arthritis (RA) is a systemic and incurable autoimmune disease characterized by chronic inflammation in synovial lining of joints. To identify the signaling pathways involved in RA, its disease activity, and treatment response, we adapted a
Externí odkaz:
https://doaj.org/article/9b1ea73e854343108c3cc3ca29f2e25a
Autor:
Jennifer A. Seifert, Elizabeth A. Bemis, Kristina Ramsden, Cassidy Lowell, Kristen Polinski, Marie Feser, Chelsie Fleischer, M. Kristen Demoruelle, Jane Buckner, Peter K. Gregersen, Richard M. Keating, Ted R. Mikuls, James R. O'Dell, Michael H. Weisman, Kevin D. Deane, Jill M. Norris, Allen C. Steere, V. Michael Holers
Publikováno v:
Arthritis & Rheumatology. 75:507-516
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01b68012dd7caca7cd8564b28c307127
https://doi.org/10.1002/art.42370
https://doi.org/10.1002/art.42370
Autor:
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Alison D. Petro, Tuhina Neogi, James R. O'Dell, Ted R. Mikuls
Publikováno v:
Arthritis Care & Research. 75:808-816
To compare all-cause and cause-specific mortality risk between patients with gout and patients without gout in the Veteran's Health Administration (VHA).We performed a matched cohort study, identifying patients with gout in the VHA from January 1999
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edfdb2895f5473ced96de6b40bca284
https://doi.org/10.1002/acr.24881
https://doi.org/10.1002/acr.24881
Autor:
Matthew R. Medcalf, Pooja Bhadbhade, Ted R. Mikuls, James R. O’Dell, Rebekah L. Gundry, Ryan S. Funk
Publikováno v:
Metabolites, Vol 11, Iss 12, p 824 (2021)
Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response
Externí odkaz:
https://doaj.org/article/a65b59be9dd14d04a4415b95ee3d7621
Autor:
Matthew C. Zimmerman, Dahn L. Clemens, Michael J. Duryee, Cleofes Sarmiento, Andrew Chiou, Carlos D. Hunter, Jun Tian, Lynell W. Klassen, James R. O’Dell, Geoffrey M. Thiele, Ted R. Mikuls, Daniel R. Anderson
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 588-593 (2017)
Methotrexate (MTX) is an immunosuppressant commonly used for the treatment of autoimmune diseases. Recent observations have shown that patients treated with MTX also exhibit a reduced risk for the development of cardiovascular disease (CVD). Although
Externí odkaz:
https://doaj.org/article/410b17d545f14444a5b35b754175626d