Zobrazeno 1 - 10
of 27
pro vyhledávání: '"James Q. Yin"'
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Neurological diseases can severely compromise both physical and psychological health. Recently, adult mesenchymal stem cell- (MSC-) based cell transplantation has become a potential therapeutic strategy. However, most studies related to the transdiff
Externí odkaz:
https://doaj.org/article/9384d62042dd4e1bbb2a933bab4aac62
Publikováno v:
Nature Biomedical Engineering. 3:90-104
Mesenchymal stromal cells (MSCs) for basic research and clinical applications are manufactured and developed as unique cell products by many different manufacturers and laboratories, often under different conditions. The lack of standardization of MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c71452d7e13831622ae71287238f7c
https://doi.org/10.1038/s41551-018-0325-8
https://doi.org/10.1038/s41551-018-0325-8
Publikováno v:
Nature biomedical engineering. 3(2)
Mesenchymal stromal cells (MSCs) for basic research and clinical applications are manufactured and developed as unique cell products by many different manufacturers and laboratories, often under different conditions. The lack of standardization of MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53b42c623f2ae3c5a601e72db42570ff
https://pubmed.ncbi.nlm.nih.gov/30944433
https://pubmed.ncbi.nlm.nih.gov/30944433
Publikováno v:
Scientific Reports
There has been recently been increased interest in the plasticity of human umbilical cord mesenchymal stem cells (UMSCs) and their potential in the treatment of neurological disorders. In this study, UMSCs were transdifferentiated into neural stem-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbe5485d439580fb39132a17bd83e4b
https://pubmed.ncbi.nlm.nih.gov/28074931
https://pubmed.ncbi.nlm.nih.gov/28074931
Autor:
Chui Liu, Guang Zhao, Yingyu Zhang, Qingqi Yang, Xiang Yi, James Q. Yin, Henming Jia, Kejun Dou, Rusong Meng, Hongjie Zhang, Fangyuan Que, Di Guan
Publikováno v:
Molecular Therapy. 19:362-371
It is unclear whether siRNA-based agents can be a safe and effective therapy for diseases. In this study, we demonstrate that microphthalmia-associated transcription factor–siRNA (MITF-siR)-silenced MITF gene expression effectively induced a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8d7c7c88ffd84d03d147d731e885a7
https://doi.org/10.1038/mt.2010.263
https://doi.org/10.1038/mt.2010.263
Publikováno v:
Toxicology. 270:49-56
Human bone marrow mesenchymal stem cells (MSCs) are important cell population located in bone marrow that are thought to have multiple functions in cell transplantation and gene therapy. Although in vitro experiments have demonstrated that hMSCs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8143b3fb6a7c08465be0ce3922988370
https://doi.org/10.1016/j.tox.2010.01.011
https://doi.org/10.1016/j.tox.2010.01.011
Publikováno v:
Cellular & Molecular Biology Letters
Although there are many reports about the efficacy of siRNAs, it is not clear whether those siRNAs with high C/G contents can be used to silence their target mRNAs efficiently. In this study, we investigated the structure and function of a group of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6292f62c6743dfe0c5464c47f0e030ec
http://europepmc.org/articles/PMC6275720
http://europepmc.org/articles/PMC6275720
Autor:
Robert Chunhua Zhao, James Q. Yin
Publikováno v:
Methods. 43:123-130
Although a large number of small RNAs (sRNAs) have been discovered, it is very likely that the screens conducted so far have not reached saturation. Recently, many methods for predicting and identifying new sRNAs have been developed. However, it rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f171bd44cc0549e00ad60340f57f38d3
https://doi.org/10.1016/j.ymeth.2007.04.010
https://doi.org/10.1016/j.ymeth.2007.04.010
Publikováno v:
Acta Pharmacologica Sinica. 28:1-9
RNA interference (RNAi) is an adaptive defense mechanism through which double stranded RNAs silence cognate genes in a sequence-specific manner. It has been employed widely as a powerful tool in functional genomics studies, target validation and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73318810fd12654de0cbf6c441236820
https://doi.org/10.1111/j.1745-7254.2007.00491.x
https://doi.org/10.1111/j.1745-7254.2007.00491.x
Publikováno v:
Liver International. 26:8-22
Hepatic fibrosis is the common wound-healing response to chronic liver injury. In this process, activation of hepatic stellate cells is characteristic of cell proliferation and migration, production of collagen and other extracellular matrix (ECM) mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193a722ff97f9c533d6f1c517936c943
https://doi.org/10.1111/j.1478-3231.2005.01192.x
https://doi.org/10.1111/j.1478-3231.2005.01192.x