Zobrazeno 1 - 10
of 14
pro vyhledávání: '"James Pretorius"'
Autor:
Chris James Pretorius
Publikováno v:
Potchefstroom Electronic Law Journal. 14:186-209
In Slip Knot Investments v Du Toit 2011 4 SA 72 (SCA) the Supreme Court of Appeal had to determine if the material mistake of a contractual party induced by the fraud of an independent third party could sustain a plea of iustus error raised by the mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff0504cc6b1fff485ea1d16f83fe96a
https://doi.org/10.17159/1727-3781/2011/v14i7a2622
https://doi.org/10.17159/1727-3781/2011/v14i7a2622
Autor:
William G. Richards, Jeff D. Reagan, Edward Shatzen, Monica Florio, Charles Henley, David J. St. Jean, Jenny Ying-Lin Lu, James W. Davis, Yuhua Yang, Christopher H. Fotsch, James Pretorius, Wei Fan, Sean Morony, Banghua Sun
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 337:681-691
Calcimimetics are positive allosteric modulators to the calcium-sensing receptor (CaSR). Activation of the CaSR inhibits the secretion of parathyroid hormone (PTH), stimulates the secretion of calcitonin, and decreases serum calcium (Ca(2+)). Cinacal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385bca994d6f67b93548f4120256f3b4
https://doi.org/10.1124/jpet.110.178681
https://doi.org/10.1124/jpet.110.178681
Autor:
Hal Blumberg, Esther S. Trueblood, Jennifer E. Towne, James Pretorius, Melanie K. Kuechle, David G. Kugler, Cynthia R. Willis, John E. Sims, Ning Weng, Huyen Dinh, Suzanne Kanaly, Jacques J. Peschon
Publikováno v:
The Journal of Experimental Medicine
The interleukin (IL)-1 family members IL-1α, -1β, and -18 are potent inflammatory cytokines whose activities are dependent on heterodimeric receptors of the IL-1R superfamily, and which are regulated by soluble antagonists. Recently, several new IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d15ccac9d75a6b4df85a8d88cbfbe20
http://europepmc.org/articles/PMC2118475
http://europepmc.org/articles/PMC2118475
Autor:
Sheila Scully, Catherine L. Farrell, Luis Borges, Ping Wei, Jennifer N. Chen, Stephen Kaufman, James Pretorius, Karen Rex
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 66:254-262
Purpose: To evaluate the activity of palifermin (rHuKGF) in a murine model of mucosal damage induced by a radiotherapy/chemotherapy (RT/CT) regimen mimicking treatment protocols used in head-and-neck cancer patients. Methods and Materials: A model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1228629c495646981dd77f83211f246e
https://doi.org/10.1016/j.ijrobp.2006.05.025
https://doi.org/10.1016/j.ijrobp.2006.05.025
Autor:
Jianhua Gong, Roy A. Black, Qing Tian Niu, Hua Z. Ke, Kevin Graham, Efrain Pacheco, James Pretorius, Martine Roudier, Xiaodong Li, Kelly S Warmington, Joanne T. Hulme, Philip Babij, Bo Rin P. Yoon
Publikováno v:
Arthritis and rheumatism. 65(3)
Objective Sclerostin plays a major role in regulating skeletal bone mass, but its effects in articular cartilage are not known. The purpose of this study was to determine whether genetic loss or pharmacologic inhibition of sclerostin has an impact on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635525984c68184556a59da65ad51454
https://pubmed.ncbi.nlm.nih.gov/23233270
https://pubmed.ncbi.nlm.nih.gov/23233270
Autor:
William Fanslow, T. Michael Nork, Linh T. Nguyen, Stephen C. Kaufman, Jonathan D. Oliner, James Pretorius, Hongjin Ma, James Bready, Robert A Leedle, Juan Estrada, Eunju Hurh, Angela Coxon
Publikováno v:
Investigative ophthalmologyvisual science. 53(4)
Purpose To determine whether systemic treatment with AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, inhibits neovascular processes in animal models of ocular disease. Methods AMG 386 was tested in a laser-induced choroidal neovasculari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f046c812a158d2097cd0e4b8ff2ec486
https://pubmed.ncbi.nlm.nih.gov/22410553
https://pubmed.ncbi.nlm.nih.gov/22410553
Autor:
Chris James Pretorius
Publikováno v:
Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad. 14
In Slip Knot Investments v Du Toit 2011 4 SA 72 (SCA) the Supreme Court of Appeal had to determine if the material mistake of a contractual party induced by the fraud of an independent third party could sustain a plea of iustus error raised by the mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcc05b35a1f058e2e9adb7a753cc1b18
https://doi.org/10.4314/pelj.v14i7.8
https://doi.org/10.4314/pelj.v14i7.8
Autor:
Debra Zack, James Pretorius, Li Zhu, Heather Brown, Marina Stolina, Scot Middleton, Paul J. Kostenuik, Ulrich Feige, Brad Bolon, Diane Duryea, Alison Rohner, Denise Dwyer
Publikováno v:
Journal of clinical immunology. 29(2)
Rats with adjuvant-induced arthritis (AIA) were necropsied on 14 occasions during preclinical, acute clinical and chronic clinical stages of AIA progression to characterize local (joint protein extracts) and systemic (serum) levels of mediators regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f451bf0ac8e31ea19908bed1cc5fcfb
https://pubmed.ncbi.nlm.nih.gov/18726678
https://pubmed.ncbi.nlm.nih.gov/18726678
Autor:
Wan-rong Qiu, Paul J. Kostenuik, Russell C. Cattley, Sean Morony, W. Scott Simonet, William G. Richards, Stephen Adamu, James Pretorius, Zhaopo Geng, Xueming Qian, Victoria Shalhoub, Ji Li, Michael S. Ominsky, Brad Bolon, Frank Asuncion, Ildiko Sarosi, Hua Zhu Ke, Mario Grisanti, Xiaodong Li, David L. Lacey
Publikováno v:
Bone. 39(4)
Mutations affecting the activity of the Wnt co-receptors LRP5 and LRP6 that cause alterations in skeletal biology confirmed the involvement of Wnt signaling in bone formation. We evaluated the potential role of Dkk1, an inhibitor of LRP5/6 activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d0c8d11a6ca5039a7995eea6213ded
https://pubmed.ncbi.nlm.nih.gov/16730481
https://pubmed.ncbi.nlm.nih.gov/16730481
Autor:
Nancy Zhang, Jonathan D. Oliner, Angela Coxon, Juan Leal, Shashirekha Rao, Xiu Tang, Qing Chen, Edward You, Anthony Ndifor, Haejin Kim, E. Davy, Joanne Ho, Luke Li, Frederick W. Jacobsen, Marc Payton, Frank Martin, Kevin Graham, Steve Coats, Karen C. Sitney, Dongyin Yu, Sheila Scully, Richard Kendall, Ji-Rong Sun, Shirley Stevenson, Seog Joon Han, Michael J. Kelley, Robert Radinsky, Mark Leo Michaels, Juan Estrada, Robert Rosenfeld, James Pretorius, Susanne Meyer, Binodh DeSilva, Russ Cattley, Linh Nguyen, Tom Boone, John Lu, Isaac J. Hayward, Hosung Min, Stephen Kaufman, Thomas Hartmann, Nessa Hawkins, Rakesh Kumar
Publikováno v:
Cancer cell. 6(5)
Angiopoietin-2 (Ang2) exhibits broad expression in the remodeling vasculature of human tumors but very limited expression in normal tissues, making it an attractive candidate target for antiangiogenic cancer therapy. To investigate the functional con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58427cebf584af13ae85da4f91475e65
https://pubmed.ncbi.nlm.nih.gov/15542434
https://pubmed.ncbi.nlm.nih.gov/15542434