Zobrazeno 1 - 10
of 28
pro vyhledávání: '"James P. Warne"'
Autor:
Stephanie M. Correa, David W. Newstrom, James P. Warne, Pierre Flandin, Clement C. Cheung, Alexander T. Lin-Moore, Andrew A. Pierce, Allison W. Xu, John L. Rubenstein, Holly A. Ingraham
Publikováno v:
Cell Reports, Vol 10, Iss 1, Pp 62-74 (2015)
Estrogen-receptor alpha (ERα) neurons in the ventrolateral region of the ventromedial hypothalamus (VMHVL) control an array of sex-specific responses to maximize reproductive success. In females, these VMHVL neurons are believed to coordinate metabo
Externí odkaz:
https://doaj.org/article/801ff2f30d0c4fd4ab3422a6a1c3505c
Autor:
Alison S. Reed, Merisa Piper, Allison W. Xu, Jillian M. Varonin, Carlos U. Corvera, Mark E. Mullin, James P. Warne, Farzad Alemi, Helen Chan, Martin G. Myers
Publikováno v:
Cell Metabolism. 14(6):791-803
Hepatic steatosis is generally thought to develop via peripheral mechanisms associated with obesity. We show that chronic central infusion of leptin suppresses hepatic lipogenic gene expression and reduces triglyceride content via stimulation of hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7755a9c752716385a004b14e9b3e7da6
Publikováno v:
Stress. 13:248-257
The hypothalamic-pituitary-adrenal (HPA) axis self-regulates through a glucocorticoid negative feedback mechanism that is stereotypically slow and long lasting. Rapid (seconds to minutes) glucocorticoid feedback, however, inhibits stress-induced adre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0941003c25e00f1fcfe63f5e6195ec
https://doi.org/10.3109/10253890903336839
https://doi.org/10.3109/10253890903336839
Autor:
Mary F. Dallman, Susan F. Akana, Norman C. Pecoraro, Hart F. Horneman, James P. Warne, Abigail B. Ginsberg
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1366-R1375
Corticosterone and insulin play complex roles in the amount and composition of calories ingested, and the utilization and deposition of this energy. Understanding the interplay of these two hormones is complicated because increasing concentrations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2dea4aca4ca88583eceb92f4ed9094
https://doi.org/10.1152/ajpregu.91016.2008
https://doi.org/10.1152/ajpregu.91016.2008
Autor:
James P. Warne
Publikováno v:
Molecular and Cellular Endocrinology. 300:137-146
Activity of the hypothalamo-pituitary-adrenal (HPA) axis is regulated by a negative feedback loop that dampens central drive of the axis via the actions of the secreted glucocorticoids. Conversely, under conditions of chronic stress, glucocorticoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8623c30aaeae89e96d2f88b2b3c4ec7
https://doi.org/10.1016/j.mce.2008.09.036
https://doi.org/10.1016/j.mce.2008.09.036
Autor:
Abigail B. Ginsberg, Mary F. Dallman, Norman C. Pecoraro, James P. Warne, Benjamin E. Padilla, Susan F. Akana, Hart F. Horneman
Publikováno v:
Annals of Surgery. 249:269-276
We sought to examine insulin-sensitive food intake behavior and neuroendocrine and metabolic variables of rats that had undergone a duodenal-jejunal bypass (DJB).A DJB that circumvents the duodenum and proximal jejunum while leaving the stomach unper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fe85016110e29a0057cb245699c0bc
https://doi.org/10.1097/sla.0b013e3181961d5d
https://doi.org/10.1097/sla.0b013e3181961d5d
Autor:
Malcolm T. Foster, Hart F. Horneman, Susan F. Akana, James P. Warne, Mary F. Dallman, Norman C. Pecoraro, Abigail B. Ginsberg
Publikováno v:
Journal of Neuroendocrinology. 19:794-808
In addition to the inhibitory role of central insulin on food intake, insulin also acts to promote lard intake. We investigated the neural pathways involved in this facet of insulin action. Insulin or saline was infused into either the superior mesen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ecae3b484c3cc6203cdb0a7ddb4986
https://doi.org/10.1111/j.1365-2826.2007.01593.x
https://doi.org/10.1111/j.1365-2826.2007.01593.x
Autor:
Michelle T. Foster, Norman C. Pecoraro, Abigail B. Ginsberg, Mary F. Dallman, Hart F. Horneman, Susan F. Akana, James P. Warne
Publikováno v:
The Journal of Physiology. 583:455-467
The common hepatic branch of the vagus nerve is a two-way highway of communication between the brain and the liver, duodenum, stomach and pancreas that regulates many aspects of food intake and metabolism. In this study, we utilized the afferent-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eaf379a58839f0ba1aec1a1b29c6def
https://doi.org/10.1113/jphysiol.2007.135996
https://doi.org/10.1113/jphysiol.2007.135996
Publikováno v:
The Journal of Physiology. 583:431-436
Glucocorticoids act primarily in a feed-forward fashion on brain to activate CNS pathways that implement wanting appropriate to physiological needs. Thus, depending on the available conditions, elevated glucocorticoids may augment the behavioural wan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd018974dd3106e33e253c45541504e0
https://doi.org/10.1113/jphysiol.2007.136051
https://doi.org/10.1113/jphysiol.2007.136051
Autor:
Hart F. Horneman, Susan F. Akana, Michelle T. Foster, Norman C. Pecoraro, Mary F. Dallman, Abigail B. Ginsberg, James P. Warne
Publikováno v:
Endocrinology. 148:3288-3298
Although high insulin concentrations reduce food intake, low insulin concentrations promote lard intake over chow, possibly via an insulin-derived, liver-mediated signal. To investigate the role of the hepatic vagus in voluntary lard intake, streptoz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46575d8ca7f7f0ea74c84453e8c9746a
https://doi.org/10.1210/en.2007-0003
https://doi.org/10.1210/en.2007-0003