Zobrazeno 1 - 10
of 56
pro vyhledávání: '"James P. Perras"'
Autor:
Laura Sharpe, Octavio Santos, James P. Perras, Dayna Cameron, Vathsala S. Basrur, Bernd Uwe Sevin, Paul G. Braunschweiger, Arnold M. Markoe
Publikováno v:
Biotherapy. 10:129-137
The modulation of cisPlatin cytotoxicity by interleukin-1 (IL-1 alpha) was studied in cultures of SCC-7 tumor cells with and without tumor macrophages to examine potential mechanisms for the synergistic antitumor activity of cisPlatin and IL-1 alpha
Autor:
Bernd-Uwe Sevin, James P. Perras
Publikováno v:
American Journal of Obstetrics and Gynecology. 176:759-768
OBJECTIVE: Our purpose was to study the heterogeneity of drug response in fresh human ovarian tumors to chemotherapeutic agents in an in vitro chemosensitivity assay. STUDY DESIGN: This assay evaluates total tumor cell kill by measuring the intracell
Autor:
Roberto Angioli, Michael Untch, James P. Perras, Ossi R. Koechli, Andrea Untch, Hervy E. Averette, Bernd-Uwe Sevin
Publikováno v:
Anti-Cancer Drugs. 5:24-30
The in vitro effects of paclitaxel (Tx) and docetaxel (Taxotere, Txt) are compared in this study using the adenosine triphosphate cell viability assay (ATP-CVA) in 14 cancer cell lines. Eleven cell lines were sensitive and three were partially sensit
Autor:
P. Steindorfer, K. Stevens, Arnold Lockshin, M. Schmid, Rüdiger E. Port, H. Samonigg, Michael Untch, Ivan G. Strukov, Tatsuhei Kondo, Stan Ivankovic, Osamu Doi, I. Kuss, J. García-Conde, A. Uys, A.K. Kasparek, Shuichi Okada, Tokuhiro Kawashima, Hideoki Yokouchi, S.H. Schmitz, J. Schimke, Masaji Yamauchi, Valentina I. Ryabkova, Miyako Kawashima, Cheppail Ramachandran, W.J.H. Vermaak, E. Derstvenscheg, C. Lackner, Carla I. Falkson, Takuji Okusaka, H. Stöger, Luis Fonseca, Akio Yamaguchi, Yutaka Yonemura, F. Jarque, Roberto Angioli, Shoshana Keren-Rosenberg, Masahiro Kanno, Masahiro Yoshino, Hideki Yokoyama, Mokoto Uogishi, Masayoshi Yoshimori, Masahiko Iwasaki, James P. Perras, M. Wilders-Truschnig, Geoffrey Falkson, Kazunori Aoki, Yoshitaka Sato, Takashi Inoue, Koichi Miwa, Valentina K. Sokolova, Itsuo Miyazaki, Junji Furuse, Albert Steren, T. Bauernhofer, Hiroshi Asoh, Hiroshi Ishii, Xabier De Aretxabala, Hajime Arakawa, Kimio Wada, Masahiko Higashiyama, Kiichi Maeda, Ryuhei Tateishi, Hiroshi Sodani, B.L. Rapoport, R.M. Moser, Ken Kodama, V. Diehl, D.L. Voliotis, A. Lluch, Ossi R. Koechli, Haruhiko Nose, F. Ploner, Yukito Ichinose, Klaus Blaszkiewitz, Hiroyuki Takamura, Nobuko Takanashi, Hervy E. Averette, G. Falkson, E. Vizcarra, R. Cibrián, M. de Wet, Tokujiro Yano, Bernd-Uwe Sevin, Susanne R. Kempf, Hironobu Kimura
Publikováno v:
Oncology. 51:I-VI
Autor:
Parvin Ganjei, Mike Rodriguez, Bernd Uwe Sevin, James P. Perras, Roberto Angioli, Albert Steren, Ossi R. Koechli, Hervy E. Averette
Publikováno v:
Oncology. 51:35-41
Over the last 5 years, the ATP cell viability assay (ATP-CVA) has been used to study the in vitro response of cell lines and fresh gynecologic human tumors to a variety of antineoplastic agents including chemotherapeutic agents, hormones and biologic
Autor:
James P. Perras, Ossi R. Koechli, Bernd-Uwe Sevin, David S. Robinson, Barry P. Avner, Belina Avner, Hervy E. Averette
Publikováno v:
Journal of Surgical Oncology. 54:119-125
Chemosensitivity testing in vitro of breast cancer has been difficult because of small tumor volume, an even smaller yield of viable cells after disaggregation, and the low evaluability rate and sensitivity of current assays. We have employed an alte
Autor:
James P. Perras, Roberto Angioli, Hervy E. Averette, Michael Untch, James G. Schwade, Albert Steren, Bernd-Uwe Sevin, Hoa N. Nguyen, Ossi R. Koechli, Corrado Villani
Publikováno v:
Cancer. 71:3717-3725
Background. This investigation, which evaluates the combination of radiation and interferon, bridges two clinical treatments of cancer. Radiation therapy (RT) is an integral part of cervical cancer treatment; interferons (IFN), however, are classifie
Autor:
Ossi R. Koechli, Albert Steren, Roberto Angioli, Bernd-Uwe Sevin, Hervy E. Averette, James P. Perras, Michael Untch, Hoa N. Nguyen, Randall D. Hightower
Publikováno v:
Cancer. 71:2776-2781
Background. Interferon (IFN) has been reported to increase hormone receptor expression in breast cancer cells and to sensitize them to antiproliferative hormones. Endometrial cancer cells with high progesterone receptor (PR) level respond better to p
Autor:
Parvin Ganjei, B S Reinaldo Ramos, Bernd-Uwe Sevin, James P. Perras, Hervy E. Averette, Hoa N. Nguyen
Publikováno v:
Cancer. 71:2543-2550
BACKGROUND: The incidence and significance of tumor heterogeneity in primary tumors and metastatic lymph nodes were investigated in Stage IB-IIA cervical cancers. METHODS: Paraffin-embedded tissues from 96 radical hysterectomy specimens were dewaxed,
Publikováno v:
Cancer. 71:1613-1620
Most patients with ovarian cancer currently are treated primarily with surgery and chemotherapy. Drug selection usually is not based on individualized in vitro sensitivity studies but on reported response rates of clinical trials. Attempts to include