Zobrazeno 1 - 10
of 129
pro vyhledávání: '"James P. O'Neil"'
Autor:
Richard M. Tsai, Alexandre Bejanin, Orit Lesman-Segev, Renaud LaJoie, Adrienne Visani, Viktoriya Bourakova, James P. O’Neil, Mustafa Janabi, Suzanne Baker, Suzee E. Lee, David C. Perry, Lynn Bajorek, Anna Karydas, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Eliana M. Ramos, Giovanni Coppola, Maria Luisa Gorno-Tempini, Bruce L. Miller, Howard J. Rosen, William Jagust, Adam L. Boxer, Gil D. Rabinovici
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-18 (2019)
Abstract Background The tau positron emission tomography (PET) ligand 18F-flortaucipir binds to paired helical filaments of tau in aging and Alzheimer’s disease (AD), but its utility in detecting tau aggregates in frontotemporal dementia (FTD) is u
Externí odkaz:
https://doaj.org/article/1733aae59d224cd5a72a1f4f4fc79342
Autor:
Leonardo Iaccarino, Gautam Tammewar, Nagehan Ayakta, Suzanne L. Baker, Alexandre Bejanin, Adam L. Boxer, Maria Luisa Gorno-Tempini, Mustafa Janabi, Joel H. Kramer, Andreas Lazaris, Samuel N. Lockhart, Bruce L. Miller, Zachary A. Miller, James P. O'Neil, Rik Ossenkoppele, Howard J. Rosen, Daniel R. Schonhaut, William J. Jagust, Gil D. Rabinovici
Publikováno v:
NeuroImage: Clinical, Vol 17, Iss , Pp 452-464 (2018)
The relationships between β-amyloid (Aβ), tau and neurodegeneration within Alzheimer's Disease pathogenesis are not fully understood. To explore these associations in vivo, we evaluated 30 Aβ PET-positive patients (mean±sd age 62.4±8.3) with mil
Externí odkaz:
https://doaj.org/article/a8dda70402cc446f8048fa97782ec1b1
Autor:
Sang Won Seo, Nagehan Ayakta, Lea T. Grinberg, Sylvia Villeneuve, Manja Lehmann, Bruce Reed, Charles DeCarli, Bruce L. Miller, Howard J. Rosen, Adam L. Boxer, James P. O’Neil, Lee-Way Jin, William W. Seeley, William J. Jagust, Gil D. Rabinovici
Publikováno v:
NeuroImage: Clinical, Vol 13, Iss C, Pp 130-137 (2017)
Imaging-pathological correlation studies show that in vivo amyloid-β (Aβ) positron emission tomography (PET) strongly predicts the presence of significant Aβ pathology at autopsy. We sought to determine whether regional PiB-PET uptake would improv
Externí odkaz:
https://doaj.org/article/43466c444fff4e19a703f48d0c0708f9
Autor:
Rik Ossenkoppele, Leonardo Iaccarino, Daniel R. Schonhaut, Jesse A. Brown, Renaud La Joie, James P. O'Neil, Mustafa Janabi, Suzanne L. Baker, Joel H. Kramer, Maria-Luisa Gorno-Tempini, Bruce L. Miller, Howard J. Rosen, William W. Seeley, William J. Jagust, Gil D. Rabinovici
Publikováno v:
NeuroImage: Clinical, Vol 23, Iss , Pp - (2019)
According to the network model of neurodegeneration, the spread of pathogenic proteins occurs selectively along connected brain regions. We tested in vivo whether the distribution of filamentous tau (measured with [18F]flortaucipir-PET), fibrillar am
Externí odkaz:
https://doaj.org/article/89b96f6246534672a807993293597f51
Autor:
Jennifer S. Huber PhD, Andrew M. Hernandez PhD, Mustafa Janabi PhD, James P. O’Neil PhD, Kathleen M. Brennan DVM, Stephanie T. Murphy BS, Youngho Seo PhD, Grant T. Gullberg PhD
Publikováno v:
Molecular Imaging, Vol 16 (2017)
Using longitudinal micro positron emission tomography (microPET)/computed tomography (CT) studies, we quantified changes in myocardial metabolism and perfusion in spontaneously hypertensive rats (SHRs), a model of left ventricular hypertrophy (LVH).
Externí odkaz:
https://doaj.org/article/2d2b87149466485692d648b188da6e85
Autor:
Johanna Peeples, Sang-Hyon Chu, James P. O’Neil, Mustafa Janabi, Bruce Wieland, Matthew Stokely
Publikováno v:
Instruments, Vol 3, Iss 1, p 8 (2019)
Boron nitride nanotubes (BNNTs) were investigated as a target media for cyclotron production of 11C for incident beam energy at or below 11 MeV. Both the 11B(p,n)11C and 14N(p,α)11C nuclear reactions were utilized. A sweep gas of nitrogen or helium
Externí odkaz:
https://doaj.org/article/c60a8f80ee584ca4bca7df1ea7cfbb5c
Publikováno v:
Head & Neck. 42:3125-3132
The International Federation of Head and Neck Oncologic Societies and Memorial Sloan Kettering Cancer Center in New York have partnered to create the Global On Line Fellowship program, a postgraduate fellowship training opportunity for candidates all
Autor:
Christopher C. Rowe, Lee-Way Jin, Adam L. Boxer, Victor L. Villemagne, Bruce L. Miller, Renaud La Joie, Catriona L. McLean, Vincent Dore, Orit H. Lesman-Segev, Lea T. Grinberg, Joseph E. Parisi, Prashanthi Vemuri, Chester A. Mathis, Eric J. Huang, John M Olichney, Ronald C. Petersen, William W. Seeley, Howard J. Rosen, Val J. Lowe, Samuel N. Lockhart, William E. Klunk, Milos D. Ikonomovic, Colin L. Masters, Charles DeCarli, William J. Jagust, Gil D. Rabinovici, James P. O'Neil, Dan M Mungas, Nagehan Ayakta, Salvatore Spina, Melissa E. Murray, Ji Hye Hwang, Clifford R. Jack, Julia Kofler, Ewa Borys
Publikováno v:
Alzheimer's & Dementia. 15:205-216
Introduction We sought to establish the relationships between standard postmortem measures of AD neuropathology and antemortem [ 11 C]PIB–positron emission tomography ([ 11 C]PIB-PET) analyzed with the Centiloid (CL) method, a standardized scale fo
Autor:
Eoin F. Cleere, Thomas J. Crotty, Justin M. Hintze, Conall W. R. Fitzgerald, John Kinsella, Paul Lennon, Conrad V. I. Timon, Robbie S. R. Woods, Neville P. Shine, James P. O'Neill
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 8, Iss 6, Pp 1673-1684 (2023)
Abstract Background Questions exist regarding patient selection for surgery in anaplastic thyroid carcinoma (ATC), particularly with the advent of neoadjuvant‐targeted therapeutics. The present scoping review sought to evaluate what extent of surgi
Externí odkaz:
https://doaj.org/article/e6e7dba1616c4f01a2c23ebdd77c8a81
Autor:
Adrienne Visani, Julie Pham, David C. Perry, Jesse A. Brown, Mustafa Janabi, Lauren Edwards, Renaud La Joie, Jungho Cha, Suzanne L. Baker, Howard J. Rosen, Bruce L. Miller, William J. Jagust, William W. Seeley, Kiran Chaudhary, Viktoriya Bourakova, Leonardo Iaccarino, Orit H. Lesman-Segev, Richard M. Tsai, James P. O'Neil, Julio C. Rojas, Gil D. Rabinovici, Zachary A. Miller
Publikováno v:
Sci Transl Med
Science translational medicine, vol 12, iss 524
Science translational medicine, vol 12, iss 524
β-Amyloid plaques and tau-containing neurofibrillary tangles are the two neuropathological hallmarks of Alzheimer's disease (AD) and are thought to play crucial roles in a neurodegenerative cascade leading to dementia. Both lesions can now be visual