Zobrazeno 1 - 10
of 97
pro vyhledávání: '"James P. O'Brien"'
Autor:
Michelle L. Manni, Victoria A. Heinrich, Gregory J. Buchan, James P. O’Brien, Crystal Uvalle, Veronika Cechova, Adolf Koudelka, Dharti Ukani, Mohamad Rawas-Qalaji, Tim D. Oury, Renee Hart, Madeline Ellgass, Steven J. Mullett, Merritt L. Fajt, Sally E. Wenzel, Fernando Holguin, Bruce A. Freeman, Stacy G. Wendell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Bile acid profiles are altered in obese individuals with asthma. Thus, we sought to better understand how obesity-related systemic changes contribute to lung pathophysiology. We also test the therapeutic potential of nitro-oleic acid (NO2-OA
Externí odkaz:
https://doaj.org/article/40111bfc71bc4fc1b5f339c0101d5c5d
Publikováno v:
Clinical and Experimental Emergency Medicine, Vol 11, Iss 1, Pp 22-32 (2024)
Airway management is a common procedure within emergency and critical care medicine. Traditional techniques for predicting and managing a difficult airway each have important limitations. As the field has evolved, point-of-care ultrasound has been in
Externí odkaz:
https://doaj.org/article/2ce9294c941e489e9ddf802950af7cde
Publikováno v:
Harvard Kennedy School Misinformation Review, Vol 2, Iss 3 (2021)
Despite the ubiquity of images and videos in online news environments, much of the existing research on misinformation and its correction is solely focused on textual misinformation, and little is known about how ordinary users evaluate fake or manip
Externí odkaz:
https://doaj.org/article/8707a03629bf43aead5b4c5bb02c80e8
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 18, Iss , Pp - (2020)
Externí odkaz:
https://doaj.org/article/68cd02d686ea466f9718db7201894a2a
Publikováno v:
Physics Letters B, Vol 782, Iss , Pp 433-439 (2018)
In a recent paper McGaugh, Lelli, and Schombert showed that in an empirical plot of the observed centripetal accelerations in spiral galaxies against those predicted by the Newtonian gravity of the luminous matter in those galaxies the data points oc
Externí odkaz:
https://doaj.org/article/06f51dfce5b74b4984e7a21a2a11559a
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226035 (2019)
Understanding the regulation of development can help elucidate the pathogenesis behind many developmental defects found in humans and other vertebrates. Evidence has shown that alternative splicing of messenger RNA (mRNA) plays a role in developmenta
Externí odkaz:
https://doaj.org/article/8b7c4870a04e4e97b447d3840b135da1
Autor:
John Nemunaitis, James P. O'Brien, Pallavi Sachdev, Corina Andresen, Cynthia Bedell, Jennifer Mink, Min Ren, Robert Shumaker, Lucy Xu, Goldy C. George, Ly M. Nguyen, Michael A. Davies, Kevin B. Kim, Siqing Fu, Gerald S. Falchook, Aung Naing, Jennifer J. Wheler, Razelle Kurzrock, David S. Hong
Supplementary Tables S1 and S2. Supplementary Table 1. Univariate Cox proportional hazard model analysis using baseline and change in levels of biomarkers with PFS Supplementary Table 2. Multivariate Cox proportional hazard model analysis using basel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f763894bc770dba6ac95ef69cfb9c40
https://doi.org/10.1158/1078-0432.22458195
https://doi.org/10.1158/1078-0432.22458195
Autor:
Matthew G. Vander Heiden, Massimo Loda, Lewis C. Cantley, Craig J. Thomas, James W. Horner, Ronald A. DePinho, Abhishek Jha, Kevin D. Courtney, Pier Paolo Pandolfi, Arkaitz Carracedo, Gary Bellinger, Scott Malstrom, Giuseppe Nicolò Fanelli, Howard H. Mak, Elizaveta Freinkman, Roderick T. Bronson, Raghav Sehgal, Talya L. Dayton, William J. Israelsen, Amy C. Liu, James P. O'Brien, Julia E. Heyman, Daniel R. Schmidt, Shawn M. Davidson
Supplementary Data from Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec56a440e6d09b274aab5807975bc11
https://doi.org/10.1158/0008-5472.22432293.v1
https://doi.org/10.1158/0008-5472.22432293.v1
Autor:
Josep Tabernero, José Baselga, Maria Josepa Carreras, Erik A.C. Wiemer, Yoshiharu Mizui, Maja J.A. de Jonge, Adelaida Piera, James P. O'Brien, Herman Burger, Francisco J. Ramos, Ferry A.L.M. Eskens
CCR Translation for This Article from Phase I Pharmacokinetic and Pharmacodynamic Study of the First-in-Class Spliceosome Inhibitor E7107 in Patients with Advanced Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbdde1c1e931bfc90e466159624880c
https://doi.org/10.1158/1078-0432.22452234.v1
https://doi.org/10.1158/1078-0432.22452234.v1
Autor:
Matthew G. Vander Heiden, Massimo Loda, Lewis C. Cantley, Craig J. Thomas, James W. Horner, Ronald A. DePinho, Abhishek Jha, Kevin D. Courtney, Pier Paolo Pandolfi, Arkaitz Carracedo, Gary Bellinger, Scott Malstrom, Giuseppe Nicolò Fanelli, Howard H. Mak, Elizaveta Freinkman, Roderick T. Bronson, Raghav Sehgal, Talya L. Dayton, William J. Israelsen, Amy C. Liu, James P. O'Brien, Julia E. Heyman, Daniel R. Schmidt, Shawn M. Davidson
Altered metabolism helps sustain cancer cell proliferation and survival. Most cancers, including prostate cancers, express the M2 splice isoform of pyruvate kinase (PKM2), which can support anabolic metabolism to support cell proliferation. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998775ab4ef0d96e4aac5fba5eba50ea
https://doi.org/10.1158/0008-5472.c.6514104.v1
https://doi.org/10.1158/0008-5472.c.6514104.v1