Zobrazeno 1 - 10
of 95
pro vyhledávání: '"James P. Kesby"'
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionAlthough schizophrenia is associated with a broad range of symptoms including hallucinations, delusions, and reduced motivation, measures of cognitive dysfunction, including cognitive flexibility and executive function, are the strongest
Externí odkaz:
https://doaj.org/article/b9e6910378454361915ff2a5e91a5a97
Publikováno v:
Schizophrenia, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract One of the most robust neurochemical abnormalities reported in patients with schizophrenia is an increase in dopamine (DA) synthesis and release, restricted to the dorsal striatum (DS). This hyper functionality is strongly associated with ps
Externí odkaz:
https://doaj.org/article/0651a5f94a6f4e14a1576dbc924f33d7
Autor:
Urska Arnautovska, Kathryn Vitangcol, James P. Kesby, Nicola Warren, Susan L. Rossell, Erica Neill, Anthony Harris, Cherrie Galletly, David Castle, Dan Siskind
Publikováno v:
Schizophrenia Research: Cognition, Vol 33, Iss , Pp 100283- (2023)
Objective: In the general population, repeated cognitive testing produces learning effects with potential for improved test performance. It is currently unclear whether the same effect of repeated cognitive testing on cognition pertains to people liv
Externí odkaz:
https://doaj.org/article/8c49cff4c92d4984aa6bc9d21b33a3a4
Publikováno v:
Biological Psychiatry Global Open Science, Vol 3, Iss 1, Pp 33-46 (2023)
The processing of salient and rewarding stimuli is integral to engaging our attention, stimulating anticipation for future events, and driving goal-directed behaviors. Widespread impairments in these processes are observed in psychosis, which may be
Externí odkaz:
https://doaj.org/article/cc9ac7bea41f4af2a9c4412b202b0816
Autor:
Alice Petty, Xiaoying Cui, Asad Ali, Zilong Du, Sunil Srivastav, James P. Kesby, Deniz Kirik, Oliver Howes, Darryl Eyles
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract An increase in dopamine (DA) synthesis capacity in the dorsal striatum (DS) during the prodromal stage of schizophrenia becomes more pronounced as patients progress to the full disorder. Understanding this progression is critical to interven
Externí odkaz:
https://doaj.org/article/041501d82fe64bce8596a7893fcb044b
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Schizophrenia is characterized by positive, negative and cognitive symptoms. All current antipsychotic treatments feature dopamine-receptor antagonism that is relatively effective at addressing the psychotic (positive) symptoms of schizophrenia. Howe
Externí odkaz:
https://doaj.org/article/661f9a6820b34ecab5078d528d177dc9
Autor:
Xiaoying Cui, Renata Ap. Nedel Pertile, Zilong Du, Wei Wei, Zichun Sun, Darryl W. Eyles, James P. Kesby
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7268 (2021)
The dopaminergic (DA) system is important for a range of brain functions and subcortical DA development precedes many cortical maturational processes. The dysfunction of DA systems has been associated with neuropsychiatric disorders such as schizophr
Externí odkaz:
https://doaj.org/article/c186df070bf348f9ba68aef5e730b098
Publikováno v:
Neuropharmacology. 234:109550
Autor:
Urska Arnautovska, James P Kesby, Nicole Korman, Amanda L Rebar, Justin Chapman, Nicola Warren, Susan L Rossell, Frances L Dark, Dan Siskind
Publikováno v:
Neuropsychiatric Disease and Treatment.
Urska Arnautovska,1,2 James P Kesby,3,4 Nicole Korman,1,2 Amanda L Rebar,5 Justin Chapman,2,3 Nicola Warren,1,2 Susan L Rossell,6,7 Frances L Dark,1,2 Dan Siskind1,2,4 1Faculty of Medicine, The University of Queensland, Woolloongabba, QLD, Australia;
Autor:
Shuichi Suetani, Andrea Baker, Kelly Garner, Peter Cosgrove, Matilda Mackay-Sim, Dan Siskind, Graham K Murray, James G Scott, James P. Kesby
Funder: The University of Queensland
Cognitive impairment in psychosis is one of the strongest predictors of functional decline. Problems with decision-making processes, such as goal-directed action and reversal learning, can reflect cortico-str
Cognitive impairment in psychosis is one of the strongest predictors of functional decline. Problems with decision-making processes, such as goal-directed action and reversal learning, can reflect cortico-str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f4347b690e23f81d27d985d779bec9
https://www.repository.cam.ac.uk/handle/1810/342754
https://www.repository.cam.ac.uk/handle/1810/342754