Zobrazeno 1 - 10
of 43
pro vyhledávání: '"James P. Jarvis"'
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Although genome-wide association studies (GWAS) have identified multiple regions conferring genetic risk for juvenile idiopathic arthritis (JIA), we are still faced with the task of identifying the single nucleotide polymorphisms
Externí odkaz:
https://doaj.org/article/098fccfca55a417aaff71d5905676db1
Autor:
Wendy M. Fernandes, Nicola Harris, Ane Zamalloa, Lissette Adofina, Parthi Srinivasan, Krishna Menon, Nigel Heaton, Rosa Miquel, Yoh Zen, Geoff Kelly, James A. Jarvis, Alain Oregioni, Shilpa Chokshi, Antonio Riva, I. Jane Cox
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8924 (2024)
The global burden of liver cancer is increasing. Timely diagnosis is important for optimising the limited available treatment options. Understanding the metabolic consequences of hepatocellular carcinoma (HCC) may lead to more effective treatment opt
Externí odkaz:
https://doaj.org/article/128885824d1b46bfb3233aa17e04a5ab
Autor:
Elizabeth A. Crinzi, Emma K. Haley, Kerry E. Poppenberg, Kaiyu Jiang, Vincent M. Tutino, James N. Jarvis
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionGenome wide association studies (GWAS) have identified multiple regions that confer genetic risk for the polyarticular/oligoarticular forms of juvenile idiopathic arthritis (JIA). However, genome-wide scans do not identify the cells impac
Externí odkaz:
https://doaj.org/article/57ad3efa5a64444db7d2fde87f0b8a20
Autor:
Kerry E. Poppenberg, Haley R. Zebraski, Naval Avasthi, Muhammad Waqas, Adnan H. Siddiqui, James N. Jarvis, Vincent M. Tutino
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Background Genome-wide association studies have identified many single nucleotide polymorphisms (SNPs) associated with increased risk for intracranial aneurysm (IA). However, how such variants affect gene expression within IA is poorly under
Externí odkaz:
https://doaj.org/article/7acd9b8462aa40ada5a5d2e876e2eab9
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Background Genetic variants in the human leukocyte antigen (HLA) locus contribute to the risk for developing scleroderma/systemic sclerosis (SSc). However, there are other replicated loci that also contribute to genetic risk for SSc, and it
Externí odkaz:
https://doaj.org/article/491870abb8db437d9def63a1129d7fb9
Autor:
Evan Tarbell, Kaiyu Jiang, Teresa R. Hennon, Lucy Holmes, Sonja Williams, Yao Fu, Patrick M. Gaffney, Tao Liu, James N. Jarvis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases in children. While clinical outcomes for patients with juvenile JIA have improved, the underlying biology of the disease and mechanisms underlying therapeutic res
Externí odkaz:
https://doaj.org/article/0e8fdf375c2a4a7794e76c20764ae53c
Autor:
Kerry E. Poppenberg, Vincent M. Tutino, Lu Li, Muhammad Waqas, Armond June, Lee Chaves, Kaiyu Jiang, James N. Jarvis, Yijun Sun, Kenneth V. Snyder, Elad I. Levy, Adnan H. Siddiqui, John Kolega, Hui Meng
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background Intracranial aneurysms (IAs) are dangerous because of their potential to rupture. We previously found significant RNA expression differences in circulating neutrophils between patients with and without unruptured IAs and trained m
Externí odkaz:
https://doaj.org/article/0eab8284ab3f4918bc618a1573f0df3a
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/9111ba706e0b4d548abe0b434065fa88
Autor:
Kerry E. Poppenberg, Kaiyu Jiang, Lu Li, Yijun Sun, Hui Meng, Carol A. Wallace, Teresa Hennon, James N. Jarvis
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-10 (2019)
Abstract Background The response to treatment for juvenile idiopathic arthritis (JIA) can be staged using clinical features. However, objective laboratory biomarkers of remission are still lacking. In this study, we used machine learning to predict J
Externí odkaz:
https://doaj.org/article/5b21e4fb03f8484b9ca1d9520dfb0742
Autor:
Kerry E. Poppenberg, Kaiyu Jiang, Michael K. Tso, Kenneth V. Snyder, Adnan H. Siddiqui, John Kolega, James N. Jarvis, Hui Meng, Vincent M. Tutino
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-15 (2019)
Abstract Background Genetics play an important role in intracranial aneurysm (IA) pathophysiology. Genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) that are linked to IA but how they affect disease pathob
Externí odkaz:
https://doaj.org/article/7fbe78b482cc4bb5a97528783d6f0298