Zobrazeno 1 - 10
of 12
pro vyhledávání: '"James P. Fandl"'
Autor:
Aldrich Thomas H, Elena Burova, Jennifer A. Griffiths, John S. Rudge, Elizabeth Pasnikowski, Thomas J. Daly, Vivian Wong, James P. Fandl, Donald M. McDonald, Gavin Thurston, Nick Papadopoulos, Ella Ioffe, George D. Yancopoulos, Christopher Daly
Publikováno v:
Proceedings of the National Academy of Sciences. 103:15491-15496
Angiopoietin (Ang)-2, a context-dependent agonist/antagonist for the vascular-specific Tie2 receptor, is highly expressed by endothelial cells at sites of normal and pathologic angiogenesis. One prevailing model suggests that in these settings, Ang-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcafc5a49a15951b10cdffe3c44533fb
https://doi.org/10.1073/pnas.0607538103
https://doi.org/10.1073/pnas.0607538103
Autor:
Thomas J. Daly, Frank Lee, James P. Fandl, Xiaobing Xu, Renta Hutabarat, Kevin Bailey, Vivien Wong, Laura Rocco Carpenter, Ellen M. Koehler-Stec, Erica Pyles, Czeslaw Radziejewski, Christopher Hartnett, Jennifer McNay, John S. Rudge, Swayampakula Ramakanth, Scott Carver, George D. Yancopoulos, Tammy T. Huang, Aris N. Economides, Neil Stahl, Michael R. Young
Publikováno v:
Nature Medicine. 9:47-52
Cytokines can initiate and perpetuate human diseases, and are among the best-validated of therapeutic targets. Cytokines can be blocked by the use of soluble receptors; however, the use of this approach for cytokines such as interleukin (IL)-1, IL-4,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89296f15df5ca8c1615ff4f9cc7e38c4
https://doi.org/10.1038/nm811
https://doi.org/10.1038/nm811
Autor:
John S. Rudge, George D. Yancopoulos, S. Davis, Ray Leidich, Lillian Ho, Ella Ioffe, Jocelyn Holash, Susan D. Croll, Patricia Boland, James P. Fandl, Michelle Russell, Kevin Bailey, Stanley J. Wiegand, Tom Daly, Czeslaw Radziejewski, Donna Hylton, Elena Burova, Nick Papadopoulos, Tammy T. Huang
Publikováno v:
Proceedings of the National Academy of Sciences. 99:11393-11398
Vascular endothelial growth factor (VEGF) plays a critical role during normal embryonic angiogenesis and also in the pathological angiogenesis that occurs in a number of diseases, including cancer. Initial attempts to block VEGF by using a humanized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac42436d0c4016d14e3acf910b3ad3bb
https://doi.org/10.1073/pnas.172398299
https://doi.org/10.1073/pnas.172398299
Autor:
N. J. Tobkes, Nikos Panayotatos, Terence E Ryan, Wayne A. Hendrickson, James P. Fandl, Ann Acheson, N. Q. Mcdonald, H. Cudny, Somesh Nigam
Publikováno v:
Journal of Biological Chemistry. 269:755-759
Neurotrophin-4 (NT-4) is the most recently discovered member of the neurotrophin family. We have expressed, refolded, and purified recombinant human NT-4 from Escherichia coli and compared it with recombinant human NT-4 secreted into the culture medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5694f5e0d338451c8e05d97de651e10a
https://doi.org/10.1016/s0021-9258(17)42414-8
https://doi.org/10.1016/s0021-9258(17)42414-8
Autor:
Trevor Stitt, Peter Tapley, James P. Fandl, Mariano Barbacid, Rüdiger Klein, Nancy Y. Ip, Lloyd A. Greene, George D. Yancopoulos, David J. Glass
Publikováno v:
Neuron. 10:137-149
We have exploited a battery of approaches to address several controversies that have accompanied the expansion of the nerve growth factor (NGF) family of neurotrophic factors and the identification of the Trk tyrosine kinases as receptors for these f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f29894ea53612a7587643e8bd09343
https://doi.org/10.1016/0896-6273(93)90306-c
https://doi.org/10.1016/0896-6273(93)90306-c
Publikováno v:
Antonie van Leeuwenhoek. 61:105-109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7eb6f56cfd07dd2f577fef77e23c79
https://doi.org/10.1007/bf00580615
https://doi.org/10.1007/bf00580615
Autor:
Vinit K, Rastogi, Conrad F, Diven, Genevieve M, Seabrook, Frank S, Genbauffe, Randy T, Bechard, James P, Fandl, Kevin G, Peters
Publikováno v:
Journal of biomolecular NMR. 23(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78b193dc0e825c028c13aafce5c21520
https://pubmed.ncbi.nlm.nih.gov/12238601
https://pubmed.ncbi.nlm.nih.gov/12238601
Autor:
James P. Fandl, George D. Yancopoulos, Anu Thadani, Joanne C. Conover, Thomas M. DeChiara, Stephen P. Squinto, Ann Acheson, Ronald M. Lindsay, Michelle Russell
Publikováno v:
Nature. 374(6521)
During the initial phase of their development, sensory neurons of the dorsal root ganglion (DRG) require target-derived trophic support for their survival, but as they mature they lose this requirement. Because many of these neurons express BDNF (bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8364bdd6da5660189cd4e41c5dc64a64
https://pubmed.ncbi.nlm.nih.gov/7700345
https://pubmed.ncbi.nlm.nih.gov/7700345
Autor:
Genevieve M. Seabrook, Vinit K. Rastogi, Frank Genbauffe, Kevin G. Peters, James P. Fandl, Randy T. Bechard, Conrad Diven
Publikováno v:
Journal of Biomolecular NMR. 23:251-252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a802e0b6a47d5c8eaf991bc5aacdc88a
https://doi.org/10.1023/a:1019846106641
https://doi.org/10.1023/a:1019846106641
Publikováno v:
Proceedings of the National Academy of Sciences. 85:8953-8957
Genetic analysis of protein secretion in Escherichia coli has identified secY/prlA and secA as components of the secretory apparatus. We have examined the roles of the secY(prlA) gene product (an integral membrane protein) and the soluble secA gene p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcd1b2910e59ca29caa01609f250ac7
https://doi.org/10.1073/pnas.85.23.8953
https://doi.org/10.1073/pnas.85.23.8953