A summary of pain and pain-related variables in the Avon Longitudinal Study of Parents and Children [version 1; peer review: 2 approved]

Autor: Abbie Jordan, Josefin Attermo Dufva, Kate Northstone, Edmund Keogh, Anthony E. Pickering, Hannah Sallis, Rebecca M. Pearson, Rachael Gooberman-Hill, Amanda Ly, James P. Dunham, Emma Fisher

Publikováno v: Wellcome Open Research, Vol 9 (2024)

Background To study pain, data on pain characteristics, possible triggers and consequences - such as the impact of pain on people’s lives - need to be available. When not collated, described and/or organised in a systematic manner, it can be diffic

Externí odkaz: https://doaj.org/article/161f8cc848b34e83a2b60caa24c37437

The Protestant Eraby Paul Tillich, and: Der Glaube bei Emil Brunnerby Lorenz Volken, and: The Religion of Philosophersby James H. Dunham (review)

Autor: Smith, Vincent Edward

Publikováno v: The Thomist: A Speculative Quarterly Review (Project Muse); June 1949, Vol. 12 Issue: 2 p220-227, 8p

Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity:a protocol for an adaptive recall by genotype study

Autor: Aidan P. Nickerson, Laura J. Corbin, Nicholas J. Timpson, Keith Phillips, Anthony E. Pickering, James P. Dunham

Publikováno v: Nickerson, A P, Corbin, L J, Timpson, N J, Phillips, K, Pickering, A E & Dunham, J 2022, ' Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity : a protocol for an adaptive recall by genotype study ', BMC Medical Genomics, vol. 15, no. 1, 9 . https://doi.org/10.1186/s12920-022-01156-5
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-11 (2022)
BMC Medical Genomics

Background Pain is a complex polygenic trait whose common genetic underpinnings are relatively ill-defined due in part to challenges in measuring pain as a phenotype. Pain sensitivity can be quantified, but this is difficult to perform at the scale r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24eee249973b7ffd4d03e8d9479eb763
https://research-information.bris.ac.uk/en/publications/636f1a91-1fc1-4e93-b9b1-13ac248b6f02

Optimal delineation of single C-tactile and C-nociceptive afferents in humans by latency slowing

Autor: Helena Backlund Wasling, Håkan Olausson, Rochelle Ackerley, James P. Dunham, Roger Holmes Watkins, Richard D. Johnson, Johan Wessberg

Publikováno v: Journal of Neurophysiology
Journal of Neurophysiology, American Physiological Society, 2017, 117 (4), pp.1608-1614. ⟨10.1152/jn.00939.2016⟩
Journal of Neurophysiology, 2017, 117 (4), pp.1608-1614. ⟨10.1152/jn.00939.2016⟩

Human skin encodes a plethora of touch interactions, and affective tactile information is primarily signaled by slowly conducting C-mechanoreceptive afferents. We show that electrical stimulation of low-threshold C-tactile afferents produces markedly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d582e72897e4c539f2839372024d91
https://hal.archives-ouvertes.fr/hal-01599597

Inflammation reduces mechanical thresholds in a population of transient receptor potential channel A1-expressing nociceptors in the rat

Autor: James P. Dunham, Lucy F. Donaldson, Sara Kelly

Publikováno v: The European Journal of Neuroscience

Inflammatory hypersensitivity is characterized by behavioural reductions in withdrawal thresholds to noxious stimuli. Although cutaneous primary afferent neurones are known to have lowered thermal thresholds in inflammation, whether their mechanical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea645a1ec921fc72031436cbdfaf479b
https://doi.org/10.1111/j.1460-9568.2008.06256.x