Zobrazeno 1 - 10
of 256
pro vyhledávání: '"James P. Chambers"'
Autor:
James P. Chambers, Miranda Aldis, Julie A. Thomas, Cara B. Gonzales, Richard Allen White, Philip Serwer
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 195-206 (2024)
Past anti-bacterial use of bacteriophages (phage therapy) is already well reviewed as a potential therapeutic response to the emergence of multidrug-resistant, pathogenic bacteria. Phage therapy has been limited by the following. (1) The success rate
Externí odkaz:
https://doaj.org/article/673047e8805e4bbf8c9310378e4e47e5
Publikováno v:
Biophysica, Vol 3, Iss 4, Pp 558-568 (2023)
Phage characterization for research and therapy can involve newly isolated phages propagated in pathogenic bacteria. If so, characterization requires safety-managing the bacteria. In the current study, we adapt a common and inexpensive reagent, Prime
Externí odkaz:
https://doaj.org/article/fbe79eec49e54c4f815c3aee25fcb6a1
Publikováno v:
Diagnostics, Vol 14, Iss 12, p 1207 (2024)
There is a significant need to develop new environmentally friendly, extraction-free sample collection mediums that can effectively preserve and protect genetic material for point-of-care and/or self-collection, home-collection, and mail-back testing
Externí odkaz:
https://doaj.org/article/2985da4df05f40ad90656655d1bac53c
Autor:
Sean Jeffreys, Megan P. Tompkins, Jadelynn Aki, Sara B. Papp, James P. Chambers, M. Neal Guentzel, Chiung-Yu Hung, Jieh-Juen Yu, Bernard P. Arulanandam
Publikováno v:
Vaccines, Vol 12, Iss 4, p 358 (2024)
Multi-drug-resistant (MDR) Acinetobacter baumannii is an opportunistic pathogen associated with hospital-acquired infections. Due to its environmental persistence, virulence, and limited treatment options, this organism causes both increased patient
Externí odkaz:
https://doaj.org/article/a6f31eddb5b34e7da2beb2a455db5c34
Publikováno v:
Diagnostics, Vol 13, Iss 18, p 3010 (2023)
Background: The rapid detection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is vital for patient care. The LumiraDx™ SARS-CoV-2 RNA Star Complete (RSC) is an Emergency Use Authorization-recognized molecular test using nasal/naso
Externí odkaz:
https://doaj.org/article/61d3a58900cb48849271ffa82007a376
Autor:
Sean Jeffreys, James P. Chambers, Jieh-Juen Yu, Chiung-Yu Hung, Thomas Forsthuber, Bernard P. Arulanandam
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Acinetobacter baumannii is a nosocomic opportunistic Gram-negative bacteria known for its extensive drug-resistant phenotype. A. baumannii hospital-acquired infections are major contributors to increased costs and mortality observed during the COVID-
Externí odkaz:
https://doaj.org/article/c140a67d3381444f940d67c7e90ce897
Publikováno v:
International Journal of Microbiology, Vol 2022 (2022)
Fetuin-A is an acute phase glycoprotein shown to counter in a regulatory manner proinflammatory cytokine production to maintain homeostasis during inflammation. We report here that in wild-type mice 12 days after Chlamydia muridarum (Cm) intranasal c
Externí odkaz:
https://doaj.org/article/97103e95f3e24be0b6d514befb3e0f85
Publikováno v:
MethodsX, Vol 6, Iss , Pp 1925-1932 (2019)
Although manual enumeration of Chlamydia inclusion forming units is the most widely accepted means of quantification in the field, it is both time consuming and subject to inherent investigator bias. We report here a rapid, i.e., minutes vs. hours, m
Externí odkaz:
https://doaj.org/article/5d3cb25378fe4036949c1b7caff7d5e7
Autor:
Jonathon Keck, James P. Chambers, Jieh-Juen Yu, Xingguo Cheng, Lane K. Christenson, M. N. Guentzel, Rishein Gupta, Bernard P. Arulanandam
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Previously, our laboratory established the role of small, noncoding RNA species, i.e., microRNA (miRNA) including miR-135a in anti-chlamydial immunity in infected hosts. We report here chlamydial infection results in decreased miR-135a expression in
Externí odkaz:
https://doaj.org/article/8901cd252ac449c5b181753f056d75f0
Publikováno v:
Journal of Pathogens, Vol 2020 (2020)
Viruses are obligate intracellular parasites, and host cell entry is the first step in the viral life cycle. The SARS-CoV-2 (COVID-19) entry process into susceptible host tissue cells is complex requiring (1) attachment of the virus via the conserved
Externí odkaz:
https://doaj.org/article/c9c0477682004b8287cd9402f022f10d