Zobrazeno 1 - 10
of 15
pro vyhledávání: '"James P. Bruzik"'
Autor:
James P. Bruzik, Jeremy R. Sanford
Publikováno v:
Proceedings of the National Academy of Sciences. 98:10184-10189
Ser-Arg-rich (SR) proteins play numerous roles in spliceosome assembly and the regulation of splice-site selection. Whereas considerable attention has focused on the mechanistic details of SR protein activities, little is known concerning how these s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5cf5c24c53ff71bf46cb9f3660c15f
https://doi.org/10.1073/pnas.181340498
https://doi.org/10.1073/pnas.181340498
Autor:
James P. Bruzik, Lisa A. Boukis
Publikováno v:
RNA. 7:793-805
The role of exonic sequences in naturally occurring trans-splicing has not been explored in detail. Here, we have identified trans-splicing enhancers through the use of an iterative selection scheme. Several classes of enhancer sequences were identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c6d31d04b68052e1ef0bb8ac07a511
https://doi.org/10.1017/s1355838201010524
https://doi.org/10.1017/s1355838201010524
Autor:
James P. Bruzik, Jeremy R. Sanford
Publikováno v:
RNA. 5:918-928
SR (ser/arg) proteins have been shown to play roles in numerous aspects of pre-mRNA splicing, including modulation of alternative splicing, commitment of substrates to the splicing pathway, and splice site communication. The last of these, splice sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89f6516f5703970be8a656dcc48a5eb
https://doi.org/10.1017/s1355838299990234
https://doi.org/10.1017/s1355838299990234
Autor:
James P. Bruzik, Tom Maniatis
Publikováno v:
Nature. 360:692-695
EXON sequences present on separate RNA molecules can be joined by trans-splicing in trypanosomatids, Euglena, and in the nematode and trematode worms1–3. Trans-splicing involves an interaction between a 5′ splice site present in a spliced leader
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2111139f771aaaf4b2599bc1dad41e22
https://doi.org/10.1038/360692a0
https://doi.org/10.1038/360692a0
Autor:
James P. Bruzik, Joan A. Steitz
Publikováno v:
Cell. 62:889-899
L. collosoma or C. elegans SL RNA sequences joined to an adenovirus intron and 3′ exon are spliced highly efficiently and accurately in HeLa nuclear extract. After inactivation of U1 snRNPs using RNAase H and a deoxyollgonucleotide complementary to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e5c5fcd8db2068594f7aef27ddc62b
https://doi.org/10.1016/0092-8674(90)90264-f
https://doi.org/10.1016/0092-8674(90)90264-f
Publikováno v:
The Journal of biological chemistry. 279(28)
Previous work demonstrated that U1 small nuclear ribonucleoprotein particle (snRNP), bound to a downstream 5' splice site, can positively influence utilization of an upstream 3' splice site via exon definition in both trans- and cis-splicing systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efee4f1ff4fd9eb620d880715f54cff
https://pubmed.ncbi.nlm.nih.gov/15131126
https://pubmed.ncbi.nlm.nih.gov/15131126
Autor:
James P. Bruzik, Jeremy R. Sanford
Serine/arginine-rich splicing factors (SR proteins) are substrates for serine phosphorylation that can regulate SR protein function. We have observed gross changes in SR protein phosphorylation during early development coincident with major zygotic g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1528d40c95299525ad303298636cd5
https://europepmc.org/articles/PMC316808/
https://europepmc.org/articles/PMC316808/
Autor:
James P. Bruzik
Publikováno v:
Microbial pathogenesis. 21(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a998b20a215089de4f97d71fd809a10
https://pubmed.ncbi.nlm.nih.gov/8878012
https://pubmed.ncbi.nlm.nih.gov/8878012
Autor:
James P. Bruzik, Tom Maniatis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(15)
Splice-site selection and alternative splicing of nuclear pre-mRNAs can be controlled by splicing enhancers that act by promoting the activity of upstream splice sites. Here we show that RNA molecules containing a 3' splice site and enhancer sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae0703009b24e78a014e468d36e6f3a
https://pubmed.ncbi.nlm.nih.gov/7624368
https://pubmed.ncbi.nlm.nih.gov/7624368