Zobrazeno 1 - 10
of 120
pro vyhledávání: '"James P. B. O'Connor"'
Autor:
Nandita M. deSouza, Aad van der Lugt, Christophe M. Deroose, Angel Alberich-Bayarri, Luc Bidaut, Laure Fournier, Lena Costaridou, Daniela E. Oprea-Lager, Elmar Kotter, Marion Smits, Marius E. Mayerhoefer, Ronald Boellaard, Anna Caroli, Lioe-Fee de Geus-Oei, Wolfgang G. Kunz, Edwin H. Oei, Frederic Lecouvet, Manuela Franca, Christian Loewe, Egesta Lopci, Caroline Caramella, Anders Persson, Xavier Golay, Marc Dewey, James P. B. O’Connor, Pim deGraaf, Sergios Gatidis, Gudrun Zahlmann, European Society of Radiology, European Organisation for Research and Treatment of Cancer
Publikováno v:
Insights into Imaging, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background Lesion/tissue segmentation on digital medical images enables biomarker extraction, image-guided therapy delivery, treatment response measurement, and training/validation for developing artificial intelligence algorithms and workfl
Externí odkaz:
https://doaj.org/article/f7b82b7c9476447e9c34cc5d0cacbeea
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/7d34583d21194792872b29602e90c1e3
Autor:
Imogen Thrussell, Jessica M. Winfield, Matthew R. Orton, Aisha B. Miah, Shane H. Zaidi, Amani Arthur, Khin Thway, Dirk C. Strauss, David J. Collins, Dow-Mu Koh, Uwe Oelfke, Paul H. Huang, James P. B. O’Connor, Christina Messiou, Matthew D. Blackledge
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundSize-based assessments are inaccurate indicators of tumor response in soft-tissue sarcoma (STS), motivating the requirement for new response imaging biomarkers for this rare and heterogeneous disease. In this study, we assess the test–ret
Externí odkaz:
https://doaj.org/article/a7683e70ad334fd4b541a7916f588e86
Autor:
Reem D. Mahmood, Danielle Shaw, Tine Descamps, Cong Zhou, Robert D. Morgan, Saifee Mullamitha, Mark Saunders, Nerissa Mescallado, Alison Backen, Karen Morris, Ross A. Little, Susan Cheung, Yvonne Watson, James P. B. O’Connor, Alan Jackson, Geoff J. M. Parker, Caroline Dive, Gordon C. Jayson
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Patients with metastatic colorectal cancer are treated with cytotoxic chemotherapy supplemented by molecularly targeted therapies. There is a critical need to define biomarkers that can optimise the use of these therapies to maxim
Externí odkaz:
https://doaj.org/article/357e10ddf5c4403488351151c9365ef5
Autor:
Gordon C. Jayson, Cong Zhou, Alison Backen, Laura Horsley, Kalena Marti-Marti, Danielle Shaw, Nerissa Mescallado, Andrew Clamp, Mark P. Saunders, Juan W. Valle, Saifee Mullamitha, Mike Braun, Jurjees Hasan, Delyth McEntee, Kathryn Simpson, Ross A. Little, Yvonne Watson, Susan Cheung, Caleb Roberts, Linda Ashcroft, Prakash Manoharan, Stefan J. Scherer, Olivia del Puerto, Alan Jackson, James P. B. O’Connor, Geoff J. M. Parker, Caroline Dive
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Identification of response biomarkers is a key step towards the development of personalised care. Here, Jayson et al. identify plasma Tie2 as a biomarker for the response of the tumor vasculature to anti-angiogenics in patients with metastatic colore
Externí odkaz:
https://doaj.org/article/51bffec067d642f8a6e2d9a8af7b2752
Autor:
Paul David Tar, Neil A. Thacker, Muhammad Babur, Grazyna Lipowska-Bhalla, Susan Cheung, Ross A. Little, Kaye J. Williams, James P. B. O’Connor
Publikováno v:
Cancers, Vol 14, Iss 9, p 2159 (2022)
Imaging biomarkers are used in therapy development to identify and quantify therapeutic response. In oncology, use of MRI, PET and other imaging methods can be complicated by spatially complex and heterogeneous tumor micro-environments, non-Gaussian
Externí odkaz:
https://doaj.org/article/1ea88080121c4b8c98aa204d6d9a7b6d
Autor:
Ali Alyami, Caroline L. Hoad, Christopher Tench, Uday Bannur, Christopher Clarke, Khalid Latief, Konstantinos Argyriou, Alan Lobo, Philip Lung, Rachel Baldwin-Cleland, Kapil Sahnan, Ailsa Hart, Jimmy K. Limdi, John Mclaughlin, David Atkinson, Geoffrey J. M. Parker, James P. B. O’Connor, Ross A. Little, Penny A. Gowland, Gordon W. Moran
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2135 (2021)
Perianal Crohn’s Disease (pCD) is a common manifestation of Crohn’s Disease. Absence of reliable disease measures makes disease monitoring unreliable. Qualitative MRI has been increasingly used for diagnosing and monitoring pCD and has shown pote
Externí odkaz:
https://doaj.org/article/74ba319f25de4b3fae15fcb087fe6c40
Autor:
Damien J. McHugh, Nuria Porta, Ross A. Little, Susan Cheung, Yvonne Watson, Geoff J. M. Parker, Gordon C. Jayson, James P. B. O’Connor
Publikováno v:
Cancers, Vol 13, Iss 2, p 240 (2021)
Imaging biomarkers require technical, biological, and clinical validation to be translated into robust tools in research or clinical settings. This study contributes to the technical validation of radiomic features from magnetic resonance imaging (MR
Externí odkaz:
https://doaj.org/article/5e453909953a40aeb946649f29ab1043
Autor:
Erich P. Huang, James P. B. O’Connor, Lisa M. McShane, Maryellen L. Giger, Philippe Lambin, Paul E. Kinahan, Eliot L. Siegel, Lalitha K. Shankar
Publikováno v:
Nature Reviews Clinical Oncology. 20(2):69-82
Computer-extracted tumour characteristics have been incorporated into medical imaging computer-aided diagnosis (CAD) algorithms for decades. With the advent of radiomics, an extension of CAD involving high-throughput computer-extracted quantitative c
Autor:
Isabella, Fornacon-Wood, Hitesh, Mistry, Corinne, Johnson-Hart, Corinne, Faivre-Finn, James P B, O'Connor, Gareth J, Price
Publikováno v:
Radiotherapy and Oncology. 176:53-58
Retrospective studies have identified a link between the average set-up error of lung cancer patients treated with image-guided radiotherapy (IGRT) and survival. The IGRT protocol was subsequently changed to reduce the action threshold. In this study