Zobrazeno 1 - 10
of 41
pro vyhledávání: '"James P. Apland"'
Autor:
Taiza H. Figueiredo, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, James P. Apland, Maria F. M. Braga
Publikováno v:
Toxics, Vol 10, Iss 8, p 409 (2022)
Acute exposure to nerve agents induces status epilepticus (SE), which can cause death or long-term brain damage. Diazepam is approved by the FDA for the treatment of nerve agent-induced SE, and midazolam (MDZ) is currently under consideration to repl
Externí odkaz:
https://doaj.org/article/ae7444cae654484ebc1b06f7044c069f
Publikováno v:
Neurobiology of Disease, Vol 133, Iss , Pp - (2020)
One of the devastating effects of acute exposure to organophosphates, like nerve agents, is the induction of severe and prolonged status epilepticus (SE), which can cause death, or brain damage if death is prevented. Seizures after exposure are initi
Externí odkaz:
https://doaj.org/article/534664fd4347437aa1d5e2756088cef5
Autor:
Sarah E Wolfe, Kevin M. Bounader, Kathleen T Pagarigan, Patrick M. McNutt, Michael Adler, Shane A. Kasten, James P. Apland, James B. Machamer, Brittany M. Winner
Publikováno v:
Archives of Toxicology. 94:3877-3891
Organophosphorus (OP) compounds inhibit central and peripheral acetylcholinesterase (AChE) activity, overstimulating cholinergic receptors and causing autonomic dysfunction (e.g., bronchoconstriction, excess secretions), respiratory impairment, seizu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00c2939a0790c97d246cc7231b2d787e
https://doi.org/10.1007/s00204-020-02858-4
https://doi.org/10.1007/s00204-020-02858-4
Autor:
James P. Apland, Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Marcio de Araujo Furtado, Maria F. M. Braga
Publikováno v:
Neuropharmacology. 181
Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to nerve agents can cause rapid death. In this review, we summarize the history of nerve agent development and use in warfare, the mechanisms by which these agents caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a5be36f2cc3f64f68da25c10a9398a
https://pubmed.ncbi.nlm.nih.gov/32898558
https://pubmed.ncbi.nlm.nih.gov/32898558
Autor:
James B, Machamer, James P, Apland, Brittany M, Winner, Sarah E, Wolfe, Kathleen T, Pagarigan, Kevin M, Bounader, Shane A, Kasten, Michael, Adler, Patrick M, McNutt
Publikováno v:
Archives of toxicology. 94(11)
Organophosphorus (OP) compounds inhibit central and peripheral acetylcholinesterase (AChE) activity, overstimulating cholinergic receptors and causing autonomic dysfunction (e.g., bronchoconstriction, excess secretions), respiratory impairment, seizu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e5c02a129e526b16859c869987e33c3
https://pubmed.ncbi.nlm.nih.gov/32691075
https://pubmed.ncbi.nlm.nih.gov/32691075
Autor:
Marcio de Araujo Furtado, Maria F. M. Braga, Taiza H. Figueiredo, Vassiliki Aroniadou-Anderjaska, James P. Apland
Publikováno v:
Annals of the New York Academy of SciencesReferences. 1479(1)
Acute nerve agent exposure induces status epilepticus (SE), which can cause brain damage or death. Research aiming at developing effective therapies for controlling nerve agent-induced SE is commonly performed in adult rats. The characteristics of ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1184fcefba085bc086712e8e7a3ab32e
https://pubmed.ncbi.nlm.nih.gov/32237259
https://pubmed.ncbi.nlm.nih.gov/32237259
Publikováno v:
Epilepsia. 59:92-99
Nerve agents are organophosphate (OP) compounds and among the most powerful poisons known to man. A terrorist attack on civilian or military populations causing mass casualties is a real threat. The OP nerve agents include soman, sarin, cyclosarin, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539fb74e4c4db66870c766bb934ab173
https://doi.org/10.1111/epi.14500
https://doi.org/10.1111/epi.14500
Autor:
Taiza H. Figueiredo, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Katia Rossetti, Maria F. M. Braga, James P. Apland
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 365:314-326
The currently Food and Drug Administration–approved anticonvulsant for the treatment of status epilepticus (SE) induced by nerve agents is the benzodiazepine diazepam; however, diazepam does not appear to offer neuroprotective benefits. This is of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5172ec4d822645aeac8ce4ec76b01207
https://doi.org/10.1124/jpet.117.245969
https://doi.org/10.1124/jpet.117.245969
Publikováno v:
Chemical Warfare Agents ISBN: 9781498769235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::555553603e53a674e2fdec87722d123d
https://doi.org/10.1201/9781498769235-18
https://doi.org/10.1201/9781498769235-18
Autor:
Vassiliki Aroniadou-Anderjaska, James P. Apland, Taiza H. Figueiredo, Maria F. M. Braga, Volodymyr I. Pidoplichko, Steven L. Miller, Eric M. Prager
Publikováno v:
Annals of the New York Academy of Sciences. 1374:17-28
One of the deleterious effects of acute nerve agent exposure is the induction of status epilepticus (SE). If SE is not controlled effectively, it causes extensive brain damage. Here, we review the neuropathology observed after nerve agent-induced SE,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed79a1fe70725485cb6af76036bd839
https://doi.org/10.1111/nyas.13028
https://doi.org/10.1111/nyas.13028