Zobrazeno 1 - 10
of 228
pro vyhledávání: '"James P Keener"'
Autor:
Kiersten Utsey, James P Keener
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1007689 (2020)
Millions of people worldwide develop foodborne illnesses caused by Salmonella enterica (S. enterica) every year. The pathogenesis of S. enterica depends on flagella, which are appendages that the bacteria use to move through the environment. Interest
Externí odkaz:
https://doaj.org/article/e61950a04096417d9cd82ed8631b88b3
Autor:
Thibaud T Renault, Anthony O Abraham, Tobias Bergmiller, Guillaume Paradis, Simon Rainville, Emmanuelle Charpentier, Călin C Guet, Yuhai Tu, Keiichi Namba, James P Keener, Tohru Minamino, Marc Erhardt
Publikováno v:
eLife, Vol 6 (2017)
The bacterial flagellum is a self-assembling nanomachine. The external flagellar filament, several times longer than a bacterial cell body, is made of a few tens of thousands subunits of a single protein: flagellin. A fundamental problem concerns the
Externí odkaz:
https://doaj.org/article/0d8e4e5410504d0ea3fe009f4a0d60a1
Autor:
Yong Zi Tan, José Rodrigues, James E. Keener, Ruixiang Blake Zheng, Richard Brunton, Brian Kloss, Sabrina I. Giacometti, Ana L. Rosário, Lei Zhang, Michael Niederweis, Oliver B. Clarke, Todd L. Lowary, Michael T. Marty, Margarida Archer, Clinton S. Potter, Bridget Carragher, Filippo Mancia
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase B EmbB involved in mycobacterial cell wall biosynthesis provides insights into the substrate binding and reaction mechanism. Mapping of the ethambutol resistance associated mutati
Externí odkaz:
https://doaj.org/article/eeb46691fab54cb4aea7d475e6b51125
Publikováno v:
Gels, Vol 7, Iss 4, p 244 (2021)
Volume phase transitions in polyeletrolyte gels play important roles in many biophysical processes such as DNA packaging, nerve excitation, and cellular secretion. The swelling and deswelling of these charged polymer gels depend strongly on their ion
Externí odkaz:
https://doaj.org/article/ca0a9c454a9245a99cdee1df9aeab57c
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Despite the common use of thrombolytic drugs, especially in stroke treatment, there are many conflicting studies on factors affecting fibrinolysis. Because of the complexity of the fibrinolytic system, mathematical models closely tied with e
Externí odkaz:
https://doaj.org/article/d863aaf2dbc74d158f8a400faec97703
Publikováno v:
SIAM J Appl Math
In [Fogelson and Keener, Phys. Rev. E, 81 (2010), 051922], we introduced a kinetic model of fibrin polymerization during blood clotting that captured salient experimental observations about how the gel branching structure depends on the conditions un
Autor:
James P. Keener, Owen L. Lewis
Publikováno v:
SIAM J Appl Math
Diffusive transport of small ionic species through mucus layers is a ubiquitous phenomenon in physiology. However, some debate remains regarding how the various characteristics of mucus (charge of the polymers themselves, binding affinity of ions wit
Publikováno v:
Gels, Vol 4, Iss 3, p 76 (2018)
Gastric mucus gel is known to exhibit dramatic and unique swelling behaviors in response to the ionic composition of the hydrating solution. This swelling behavior is important in the maintenance of the mucus layer lining the stomach wall, as the lay
Externí odkaz:
https://doaj.org/article/e2e77b879a2646db9390a20098b4286e
Publikováno v:
Gels; Volume 7; Issue 4; Pages: 244
Gels
Gels, Vol 7, Iss 244, p 244 (2021)
Gels
Gels, Vol 7, Iss 244, p 244 (2021)
Volume phase transitions in polyeletrolyte gels play important roles in many biophysical processes such as DNA packaging, nerve excitation, and cellular secretion. The swelling and deswelling of these charged polymer gels depend strongly on their ion
Publikováno v:
Physical Review E. 104
The control of transport through mucus layers is a ubiquitous phenomenon in physiological systems. Mucus is often tasked with the mediation of passive, diffusive transport of small ionic species. However, questions remain regarding how mucin gel char