Zobrazeno 1 - 10
of 228
pro vyhledávání: '"James P Keener"'
Autor:
Kiersten Utsey, James P Keener
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1007689 (2020)
Millions of people worldwide develop foodborne illnesses caused by Salmonella enterica (S. enterica) every year. The pathogenesis of S. enterica depends on flagella, which are appendages that the bacteria use to move through the environment. Interest
Externí odkaz:
https://doaj.org/article/e61950a04096417d9cd82ed8631b88b3
Autor:
Thibaud T Renault, Anthony O Abraham, Tobias Bergmiller, Guillaume Paradis, Simon Rainville, Emmanuelle Charpentier, Călin C Guet, Yuhai Tu, Keiichi Namba, James P Keener, Tohru Minamino, Marc Erhardt
Publikováno v:
eLife, Vol 6 (2017)
The bacterial flagellum is a self-assembling nanomachine. The external flagellar filament, several times longer than a bacterial cell body, is made of a few tens of thousands subunits of a single protein: flagellin. A fundamental problem concerns the
Externí odkaz:
https://doaj.org/article/0d8e4e5410504d0ea3fe009f4a0d60a1
Publikováno v:
SIAM J Appl Math
In [Fogelson and Keener, Phys. Rev. E, 81 (2010), 051922], we introduced a kinetic model of fibrin polymerization during blood clotting that captured salient experimental observations about how the gel branching structure depends on the conditions un
Autor:
James P. Keener, Owen L. Lewis
Publikováno v:
SIAM J Appl Math
Diffusive transport of small ionic species through mucus layers is a ubiquitous phenomenon in physiology. However, some debate remains regarding how the various characteristics of mucus (charge of the polymers themselves, binding affinity of ions wit
Publikováno v:
Gels; Volume 7; Issue 4; Pages: 244
Gels
Gels, Vol 7, Iss 244, p 244 (2021)
Gels
Gels, Vol 7, Iss 244, p 244 (2021)
Volume phase transitions in polyeletrolyte gels play important roles in many biophysical processes such as DNA packaging, nerve excitation, and cellular secretion. The swelling and deswelling of these charged polymer gels depend strongly on their ion
Publikováno v:
Physical Review E. 104
The control of transport through mucus layers is a ubiquitous phenomenon in physiological systems. Mucus is often tasked with the mediation of passive, diffusive transport of small ionic species. However, questions remain regarding how mucin gel char
Autor:
Sean D. Lawley, James P. Keener
Publikováno v:
SIAM Journal on Applied Mathematics. 79:551-571
A fundamental assumption of the Hodgkin--Huxley model and other conductance-based neuron models is that the average flux of ions through a stochastically gated ion channel is the product of (a) the...
Autor:
James P. Keener, Cody E. FitzGerald
Publikováno v:
Journal of Mathematical Biology. 82
Bistable switch-like behavior is a ubiquitous feature of gene regulatory networks with decision-making capabilities. Type II toxin-antitoxin (TA) systems are hypothesized to facilitate a bistable switch in toxin concentration that influences the dorm
Autor:
Cody E. FitzGerald, James P. Keener
Publikováno v:
Bulletin of Mathematical Biology. 83
Initiation and entrainment of multicellular automaticity via diffusion limited extracellular domains
Publikováno v:
Biophys J
Electrically excitable cells often spontaneously and synchronously depolarize in vitro and in vivo preparations. It remains unclear how cells entrain and autorhythmically activate above the intrinsic mean activation frequency of isolated cells with o