Zobrazeno 1 - 10
of 70
pro vyhledávání: '"James P Fawcett"'
Autor:
Courtney W Stairs, Laura Eme, Sergio A Muñoz-Gómez, Alejandro Cohen, Graham Dellaire, Jennifer N Shepherd, James P Fawcett, Andrew J Roger
Publikováno v:
eLife, Vol 7 (2018)
Under hypoxic conditions, some organisms use an electron transport chain consisting of only complex I and II (CII) to generate the proton gradient essential for ATP production. In these cases, CII functions as a fumarate reductase that accepts electr
Externí odkaz:
https://doaj.org/article/7df347d0d28a4aebb1dcd9bd1626fe87
Autor:
Angela Meccariello, Shibo Hou, Serafima Davydova, James Daniel Fawcett, Alexandra Siddall, Philip T. Leftwich, Flavia Krsticevic, Philippos Aris Papathanos, Nikolai Windbichler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Homing-based gene drives are recently proposed interventions promising the area-wide, species-specific genetic control of harmful insect populations. Here we characterise a first set of gene drives in a tephritid agricultural pest species, t
Externí odkaz:
https://doaj.org/article/9a65872066c548c68c97e6e7c8317929
Autor:
Jiri Ruzicka, Marketa Dalecka, Kristyna Safrankova, Diego Peretti, Pavla Jendelova, Jessica C. F. Kwok, James W. Fawcett
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Perineuronal nets (PNNs) enwrap mature neurons, playing a role in the control of plasticity and synapse dynamics. PNNs have been shown to have effects on memory formation, retention and extinction in a variety of animal models. It has been p
Externí odkaz:
https://doaj.org/article/50eda852b9e34524b993f97aead30346
Autor:
Enrique Asin-Garcia, Christos Batianis, Yunsong Li, James D. Fawcett, Ivar de Jong, Vitor A. P. Martins dos Santos
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract The inclusion of biosafety strategies into strain engineering pipelines is crucial for safe-by-design biobased processes. This in turn might enable a more rapid regulatory acceptance of bioengineered organisms in both industrial and environm
Externí odkaz:
https://doaj.org/article/0d818496558b43e5850f6917fd2cf2f3
Autor:
Jana Dubisova, Jana Svobodova Burianova, Lucie Svobodova, Pavol Makovicky, Noelia Martinez-Varea, Anda Cimpean, James W. Fawcett, Jessica C.F. Kwok, Sarka Kubinova
Publikováno v:
Brain Research Bulletin, Vol 181, Iss , Pp 144-156 (2022)
Hyaluronan (HA) is a core constituent of perineuronal nets (PNNs) that surround subpopulations of neurones. The PNNs control synaptic stabilization in both the developing and adult central nervous system, and disruption of PNNs has shown to reactivat
Externí odkaz:
https://doaj.org/article/ec29846fa3324243b3e954a5662e5c61
Publikováno v:
ACS Omega, Vol 6, Iss 17, Pp 11223-11230 (2021)
Externí odkaz:
https://doaj.org/article/ed789ea3174d43af9d521b58fa863636
Autor:
James W. Fawcett, Jessica C. F. Kwok
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Chondroitin sulphate and heparan sulphate proteoglycans (CSPGS and HSPGs) are found throughout the central nervous system (CNS). CSPGs are ubiquitous in the diffuse extracellular matrix (ECM) between cells and are a major component of perineuronal ne
Externí odkaz:
https://doaj.org/article/a4ebdd7202b84d35840baf71d3d9af94
Autor:
Veselina Petrova, Craig S. Pearson, Jared Ching, James R. Tribble, Andrea G. Solano, Yunfei Yang, Fiona M. Love, Robert J. Watt, Andrew Osborne, Evan Reid, Pete A. Williams, Keith R. Martin, Herbert M. Geller, Richard Eva, James W. Fawcett
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Increasing the supply of growth machinery to axons is a potential strategy for promoting repair after injury. Here the authors demonstrate that the endoplasmic reticulum adaptor molecule Protrudin provides cellular components that support axonal rege
Externí odkaz:
https://doaj.org/article/719ad1bd15824dbeb84c041f6d0b9924
Autor:
Bart Nieuwenhuis, Amanda C Barber, Rachel S Evans, Craig S Pearson, Joachim Fuchs, Amy R MacQueen, Susan van Erp, Barbara Haenzi, Lianne A Hulshof, Andrew Osborne, Raquel Conceicao, Tasneem Z Khatib, Sarita S Deshpande, Joshua Cave, Charles Ffrench‐Constant, Patrice D Smith, Klaus Okkenhaug, Britta J Eickholt, Keith R Martin, James W Fawcett, Richard Eva
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-24 (2020)
Abstract Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regenerati
Externí odkaz:
https://doaj.org/article/774319b15576431a80d815b1901eaee3
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Spinal cord interneurons (SpINs) are highly diverse population of neurons that play a significant role in circuit reorganization and spontaneous recovery after spinal cord injury. Regeneration of SpIN axons across rodent spinal injuries has been demo
Externí odkaz:
https://doaj.org/article/4a6727406e7244c1987ba6962435d825