Zobrazeno 1 - 10
of 30
pro vyhledávání: '"James P Fallon"'
Autor:
Elise A. Ajay, Alex C. Thompson, Ajmal A. Azees, Andrew K. Wise, David B. Grayden, James B. Fallon, Rachael T. Richardson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Novel stimulation methods are needed to overcome the limitations of contemporary cochlear implants. Optogenetics is a technique that confers light sensitivity to neurons via the genetic introduction of light-sensitive ion channels. By contro
Externí odkaz:
https://doaj.org/article/7106d198775f496fbdf6ef3d9fe60cd7
Autor:
Jeremy L. Pinyon, Georg vonJonquieres, Edward N. Crawford, Amr Al Abed, John M. Power, Matthias Klugmann, Cherylea J. Browne, David M. Housley, Andrew K. Wise, James B. Fallon, Robert K. Shepherd, John Y. Lin, Catherine McMahon, David McAlpine, Catherine S. Birman, Waikong Lai, Ya Lang Enke, Paul M. Carter, James F. Patrick, Robert D. Gay, Corinne Marie, Daniel Scherman, Nigel H. Lovell, Gary D. Housley
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Viral vectors and lipofection‐based gene therapies have dispersion‐dependent transduction/transfection profiles that thwart precise targeting. The study describes the development of focused close‐field gene electrotransfer (GET) techno
Externí odkaz:
https://doaj.org/article/1f120ece41dd42df991a8e5de27489c2
Autor:
Joel Villalobos, Sophie C. Payne, Glenn M. Ward, Sofianos Andrikopoulos, Tomoko Hyakumura, Richard J. MacIsaac, James B. Fallon
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Background Autonomic nerve stimulation is used as a treatment for a growing number of diseases. We have previously demonstrated that application of efferent vagus nerve stimulation (eVNS) has promising glucose lowering effects in a rat model
Externí odkaz:
https://doaj.org/article/1a577f4927ab49309bf40323f68e3349
Autor:
Sophie C. Payne, Peregrine B. Osborne, Alex Thompson, Calvin D. Eiber, Janet R. Keast, James B. Fallon
Publikováno v:
APL Bioengineering, Vol 7, Iss 4, Pp 046110-046110-13 (2023)
Real-time closed-loop control of neuromodulation devices requires long-term monitoring of neural activity in the peripheral nervous system. Although many signal extraction methods exist, few are both clinically viable and designed for extracting smal
Externí odkaz:
https://doaj.org/article/94a917faed474ebf88f9158719316baf
Autor:
Jerico V. Matarazzo, Elise A. Ajay, Sophie C. Payne, Ella P. Trang, Alex C. Thompson, Jason B. Marroquin, Andrew K. Wise, James B. Fallon, Rachael T. Richardson
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionElectrical stimulation offers a drug-free alternative for the treatment of many neurological conditions, such as chronic pain. However, it is not easy to selectively activate afferent or efferent fibers of mixed nerves, nor their function
Externí odkaz:
https://doaj.org/article/390b477cfe604745b341045cca1699a7
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory disease. Despite therapeutic advances, a significant proportion of RA patients are resistant to pharmacological treatment. Stimulation of the cervical vagus nerve is a promising alternat
Externí odkaz:
https://doaj.org/article/2830ceeb49b745a3878c6c81f14d9235
Autor:
Rachael T. Richardson, Alex C. Thompson, Andrew K. Wise, Elise A. Ajay, Niliksha Gunewardene, Stephen J. O’Leary, Paul R. Stoddart, James B. Fallon
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Optical stimulation is a paradigm-shifting approach to modulating neural activity that has the potential to overcome the issue of current spread that occurs with electrical stimulation by providing focused stimuli. But optical stimulation ei
Externí odkaz:
https://doaj.org/article/07f2283027834332ac810d3131bfc53f
Autor:
Sophie C. Payne, Glenn Ward, James B. Fallon, Tomoko Hyakumura, Johannes B. Prins, Sofianos Andrikopoulos, Richard J. MacIsaac, Joel Villalobos
Publikováno v:
Physiological Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract Vagus nerve stimulation is emerging as a promising treatment for type 2 diabetes. Here, we evaluated the ability of stimulation of the vagus nerve to reduce glycemia in awake, freely moving metabolically compromised rats. A model of type 2 d
Externí odkaz:
https://doaj.org/article/12c3de092b0f4fc5bf5b868985542b7d
Autor:
Tomoko Hyakumura, Ulises Aregueta-Robles, Wenlu Duan, Joel Villalobos, Wendy K. Adams, Laura Poole-Warren, James B. Fallon
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement disorders such as those in people with Parkinson’s disease and more recently, in psychiatric conditions like obsessive co
Externí odkaz:
https://doaj.org/article/0134d388bd7340dc9d132e0b87dc692d
Autor:
Sophie C. Payne, Nicole M. Wiedmann, Calvin D. Eiber, Agnes W. Wong, Philipp Senn, Peregrine B. Osborne, Janet R. Keast, James B. Fallon
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Bioelectronic medical devices are well established and widely used in the treatment of urological dysfunction. Approved targets include the sacral S3 spinal root and posterior tibial nerve, but an alternate target is the group of pelvic splanchnic ne
Externí odkaz:
https://doaj.org/article/8c9aa52aaff845e086f7854e142a253c