Zobrazeno 1 - 10
of 132
pro vyhledávání: '"James P, McNamara"'
Autor:
Matilde Marino Merlo, Bernardo Quiroga Souki, Michele Nieri, Agnese Bonanno, Veronica Giuntini, James A. McNamara Jr., Lorenzo Franchi
Publikováno v:
Progress in Orthodontics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Objective To compare the effects on facial soft tissues produced by maxillary expansion generated by rapid maxillary expansion (RME) versus slow maxillary expansion (SME). Materials and methods Patients in the mixed dentition were included w
Externí odkaz:
https://doaj.org/article/46de6b28e047447e88049c635e159a6e
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 6, Pp n/a-n/a (2024)
Abstract Headwater catchments play a vital role in regional water supply and ecohydrology, and a quantitative understanding of the hydrological partitioning in these catchments is critically needed, particularly under a changing climate. Recent studi
Externí odkaz:
https://doaj.org/article/cec66d81ef9f448f9f8f3c2b931f34de
Autor:
Costanza Lo Cascio, Tigran Margaryan, Ernesto Luna-Melendez, James B. McNamara, Connor I. White, William Knight, Saisrinidhi Ganta, Zorana Opachich, Claudia Cantoni, Wonsuk Yoo, Nader Sanai, Artak Tovmasyan, Shwetal Mehta
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
Histone deacetylase (HDAC) inhibitors have garnered considerable interest for the treatment of adult and pediatric malignant brain tumors. However, owing to their broad-spectrum nature and inability to effectively penetrate the blood-brain barrier, H
Externí odkaz:
https://doaj.org/article/fde3c2b5ee5b4f4fac16366a31d2b804
Publikováno v:
Frontiers in Water, Vol 4 (2022)
Snowmelt is complex under heterogeneous forest cover due to spatially variable snow surface energy and mass balances and snow accumulation. Forest canopies influence the under-canopy snowpack net total radiation energy balance by enhancing longwave r
Externí odkaz:
https://doaj.org/article/48b8ede066144de4a70a7ac8af8c331b
Publikováno v:
Dental Press Journal of Orthodontics, Vol 25, Iss 5, Pp 38-43 (2020)
ABSTRACT Objective: To evaluate a protocol for bonding metallic brackets after bleaching with hydrogen peroxide (HP). Methods: 60 extracted maxillary premolar were randomly divided into an unbleached control group and two groups bleached with a solut
Externí odkaz:
https://doaj.org/article/5d92bf6884ea4403be5ae71ddf803fc9
Autor:
Brittany Butts, PhD, Mustafa I. Ahmed, MD, Navkaranbir S. Bajaj, MD, MPH, Pamela Cox Powell, MS, Betty Pat, PhD, Silvio Litovsky, MD, Himanshu Gupta, MD, Steven G. Lloyd, MD, Thomas S. Denney, PhD, Xiaoxia Zhang, PhD, Inmaculada Aban, PhD, Sakthivel Sadayappan, PhD, MBA, James W. McNamara, PhD, Michael J. Watson, PhD, Carlos M. Ferrario, MD, James F. Collawn, PhD, Clifton Lewis, MD, James E. Davies, MD, Louis J. Dell’Italia, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 109-122 (2020)
Summary: Increasing left atrial (LA) size predicts outcomes in patients with isolated mitral regurgitation (MR). Chymase is plentiful in the human heart and affects extracellular matrix remodeling. Chymase activation correlates to LA fibrosis, LA enl
Externí odkaz:
https://doaj.org/article/8b2e10df0b604a758f656d121b3eff40
Autor:
Carla J. Greenbaum, Elisavet Serti, Katharina Lambert, Lia J. Weiner, Sai Kanaparthi, Sandra Lord, Stephen E. Gitelman, Darrell M. Wilson, Jason L. Gaglia, Kurt J. Griffin, William E. Russell, Philip Raskin, Antoinette Moran, Steven M. Willi, Eva Tsalikian, Linda A. DiMeglio, Kevan C. Herold, Wayne V. Moore, Robin Goland, Mark Harris, Maria E. Craig, Desmond A. Schatz, David A. Baidal, Henry Rodriguez, Kristina M. Utzschneider, Hendrik J. Nel, Carol L. Soppe, Karen D. Boyle, Karen Cerosaletti, Lynette Keyes-Elstein, S. Alice Long, Ranjeny Thomas, James G. McNamara, Jane H. Buckner, Srinath Sanda, for the ITN058AI EXTEND Study Team
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Background IL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in
Externí odkaz:
https://doaj.org/article/083a57294536479793c92cf07ad43e13
Autor:
Costanza Lo Cascio, James B. McNamara, Ernesto L. Melendez, Erika M. Lewis, Matthew E. Dufault, Nader Sanai, Christopher L. Plaisier, Shwetal Mehta
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Glioblastoma (GBM) is characterized by an aberrant yet druggable epigenetic landscape. One major family of epigenetic regulators, the histone deacetylases (HDACs), are considered promising therapeutic targets for GBM due to their repressive influence
Externí odkaz:
https://doaj.org/article/0c28bf317c584da09eb9a6ee5bd8d523
Autor:
Prachi Umbarkar, PhD, Anand P. Singh, PhD, Manisha Gupte, PhD, Vipin K. Verma, PhD, Cristi L. Galindo, PhD, Yuanjun Guo, MD, Qinkun Zhang, MD, James W. McNamara, PhD, Thomas Force, MD, Hind Lal, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 41-53 (2019)
Summary: The role of the transforming growth factor (TGF)-β pathway in myocardial fibrosis is well recognized. However, the precise role of this signaling axis in cardiomyocyte (CM) biology is not defined. In TGF-β signaling, SMAD4 acts as the cent
Externí odkaz:
https://doaj.org/article/36b5d53dec6545cba942228e2183c948
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundHypertrophic cardiomyopathy (HCM) is a genetic disease of the heart and the most common cause of sudden cardiac death in the young. HCM is considered a disease of the sarcomere owing to the large number of mutations in genes encoding sarcom
Externí odkaz:
https://doaj.org/article/bcb59897c9ab4fa89b2904dc91e50206