Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes

Autor: Zbigniew Dominski, Robert J. Duronio, James P. Kemp, Xiao-Cui Yang, William F. Marzluff

Publikováno v: Molecular Biology of the Cell. 32:942-955

Structured illumination microscopy revealed a core-shell organization of the Drosophila histone locus body in which the core contains active RNA polymerase II and nascent transcripts and the shell contains a pre-mRNA processing factor, suggesting a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::242815a2c31fdec7d707d24de23350a3
https://doi.org/10.1091/mbc.e20-10-0645

Coordinating transcription and replication to mitigate their conflicts in early Drosophila embryos

Autor: Chun-Yi Cho, James P. Kemp, Robert J. Duronio, Patrick H. O’Farrell

Publikováno v: Cell reports. 41(3)

Collisions between transcribing RNA polymerases and DNA replication forks are disruptive. The threat of collisions is particularly acute during the rapid early embryonic cell cycles of Drosophila when S phase occupies the entirety of interphase. We h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5cd98ddefbea8e53f7fb7ed94361c7
https://pubmed.ncbi.nlm.nih.gov/36261005

Superresolution light microscopy of the

Autor: James P, Kemp, Xiao-Cui, Yang, Zbigniew, Dominski, William F, Marzluff, Robert J, Duronio

Publikováno v: Molecular Biology of the Cell

The histone locus body (HLB) is an evolutionarily conserved nuclear body that regulates the transcription and processing of replication-dependent (RD) histone mRNAs, which are the only eukaryotic mRNAs lacking a poly-A tail. Many nuclear bodies conta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::346b0d242febda92dc2d99e01040475f
https://pubmed.ncbi.nlm.nih.gov/33788585

Food and Drug Administration-mandated Trials of Long-Acting β-Agonist Safety in Asthma. Bang for the Buck?

Autor: Scott R. Evans, James F. Donohue, James P. Kemp, Elliot Israel, Samy Suissa

Publikováno v: American journal of respiratory and critical care medicine. 197(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad10d30edd92433939af2d5bdca5d37f
https://pubmed.ncbi.nlm.nih.gov/29357261

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Autor: Paul K. Keith, Olivier Vandenplas, Sebastian L. Johnston, Alkis Togias, Ioana Agache, Paulo Augusto Moreira Camargos, Dennis M. Williams, J. Bouchard, S. Mavale-Manuel, Isabella Annesi-Maesano, Arzu Yorgancioglu, Yoshitaka Okamoto, Philippe-Jean Bousquet, Robert M. Naclerio, Paul Potter, Brian J. Lipworth, Alvaro A. Cruz, A. Ben Kheder, L.-P. Boulet, Adnan Custovic, Michael A. Kaliner, Stuart W. Stoloff, Désirée Larenas-Linnemann, Barbara P. Yawn, Magnus Wickman, W. J. Fokkens, Robyn E O'Hehir, Michael S. Blaiss, William W. Busse, H. J. Zar, Ronald Dahl, Nikolaos G. Papadopoulos, K. Ohta, T. Zuberbier, E. Valovirta, Y. Mohammad, Gianni Passalacqua, J Rosado-Pinto, G. K. Scadding, J. M. Klossek, J Mullol, David Price, Eli O. Meltzer, Richard F. Lockey, S. Ouedraogo, Carlos E. Baena-Cagnani, You Young Kim, C. van Weel, M. P. Orru, O. Kalayci, Gailen D. Marshall, K-H. Carlsen, Jean Bousquet, P. Van Cauwenberge, A.G. Chuchalin, Y. Z. Chen, Marc Humbert, Elina Toskala, Todor A. Popov, F. E. R. Simons, Charles K. Naspitz, Claus Bachert, Piotr Kuna, R. Gerth van Wijk, Marek L. Kowalski, Bodo Niggemann, Peter Burney, Osman M. Yusuf, K. Nekam, Klaus F. Rabe, Lawrence Grouse, Jean-Luc Malo, Moira Chan-Yeung, Catherine Lemière, Jing Li, Daniel A. Boakye, De Yun Wang, Niels H. Chavannes, Ewa Nizankowska-Mogilnicka, R. Emuzyte, William K. Dolen, Ruby Pawankar, Giorgio Walter Canonica, E.D. Bateman, H. Douagui, L. T. T. Le, N. Khaltaev, Giovanni Viegi, Pascal Demoly, S. Palkonen, James P. Kemp, Stephen R. Durham, Nadia Aït-Khaled, Sergio Bonini, C. M. Jackson, Judah A. Denburg

Publikováno v: Allergy. 63:8-160

Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes major illness and disability worldwide. Over 600 milli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d3239395c57a0db9fee487c3c9e2b5e
https://doi.org/10.1111/j.1398-9995.2007.01620.x