Zobrazeno 1 - 10
of 71
pro vyhledávání: '"James P, Henderson"'
Autor:
Qi Hao, Manoj K. Rathinaswamy, Kelly L. Klinge, Matthew Bratkowski, Amirhossein Mafi, Christina K. Baumgartner, Keith M. Hamel, Gesine K. Veits, Rinku Jain, Claudio Catalano, Mark Fitzgerald, Alexander W. Hird, Eunice Park, Harit U. Vora, James A. Henderson, Kenton Longenecker, Charles W. Hutchins, Wei Qiu, Giovanna Scapin, Qi Sun, Vincent S. Stoll, Chaohong Sun, Ping Li, Dan Eaton, David Stokoe, Stewart L. Fisher, Christopher G. Nasveschuk, Marcia Paddock, Michael E. Kort
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract PTPN2 (protein tyrosine phosphatase non-receptor type 2, or TC-PTP) and PTPN1 are attractive immuno-oncology targets, with the deletion of Ptpn1 and Ptpn2 improving response to immunotherapy in disease models. Targeted protein degradation ha
Externí odkaz:
https://doaj.org/article/1f2680b79836478cba894b08e1a585a6
Autor:
Huaiyu Shi, Xiangjun Wu, Shiyang Sun, Chenyan Wang, Zacharias Vangelatos, Ariel Ash-Shakoor, Costas P. Grigoropoulos, Patrick T. Mather, James H. Henderson, Zhen Ma
Publikováno v:
Bioactive Materials, Vol 10, Iss , Pp 367-377 (2022)
Focal adhesion complexes function as the mediators of cell-extracellular matrix interactions to sense and transmit the extracellular signals. Previous studies have demonstrated that cardiomyocyte focal adhesions can be modulated by surface topographi
Externí odkaz:
https://doaj.org/article/2c859944a6c8480f852fdd5ab2ccc6ff
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Costameres, as striated muscle-specific cell adhesions, anchor both M-lines and Z-lines of the sarcomeres to the extracellular matrix. Previous studies have demonstrated that costameres intimately participate in the initial assembly of myofibrils. Ho
Externí odkaz:
https://doaj.org/article/a3c669c171e9489d88b098c907c454f5
Publikováno v:
Neuroimage: Reports, Vol 2, Iss 3, Pp 100103- (2022)
Neural field theories successfully describe normal, awake mesoscale to macroscale brain activity using linearized partial differential equations that involve a Laplacian operator. These neural field theories therefore predict spatial brain activity p
Externí odkaz:
https://doaj.org/article/4749cb9380f44c2e900da98874986226
Autor:
Matthew H Van Dam, Analyn Anzano Cabras, James B Henderson, Andrew J Rominger, Cynthia Pérez Estrada, Arina D Omer, Olga Dudchenko, Erez Lieberman Aiden, Athena W Lam
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009745 (2021)
Patterns of genomic architecture across insects remain largely undocumented or decoupled from a broader phylogenetic context. For instance, it is unknown whether translocation rates differ between insect orders. We address broad scale patterns of gen
Externí odkaz:
https://doaj.org/article/45b4e7980ea741cc9037bca5ac6b5e28
Publikováno v:
NeuroImage, Vol 235, Iss , Pp 117989- (2021)
It is shown how the brain’s linear transfer function provides a means to systematically analyze brain connectivity and dynamics, and to infer connectivity, eigenmodes, and activity measures such as spectra, evoked responses, coherence, and causalit
Externí odkaz:
https://doaj.org/article/7da5689b947141819d0f1b019cbb1e39
Autor:
Peter A. Robinson, James A. Henderson, Natasha C. Gabay, Kevin M. Aquino, Tara Babaie-Janvier, Xiao Gao
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
Spectral analysis based on neural field theory is used to analyze dynamic connectivity via methods based on the physical eigenmodes that are the building blocks of brain dynamics. These approaches integrate over space instead of averaging over time a
Externí odkaz:
https://doaj.org/article/49dd55b02435487082ca62d12e4625a8
Publikováno v:
Hepatology Communications, Vol 3, Iss 11, Pp 1510-1519 (2019)
Hepatic encephalopathy (HE) is a devastating complication of cirrhosis. Data are limited regarding the incidence of and risk factors for HE among contemporary patients in the context of the shifting epidemiology of cirrhosis. We examined a 20% random
Externí odkaz:
https://doaj.org/article/479c4fff57ab4c9ca932e8a808f9d12c
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 12, Pp 3945-3952 (2018)
As the barred owl (Strix varia; Aves: Strigiformes: Strigidae) expands throughout western North America, hybridization between barred and spotted owls (Strix varia and S. occidentalis, respectively), if abundant, may lead to genetic swamping of the e
Externí odkaz:
https://doaj.org/article/9e637f0596954c85b633534c9eeb8276
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract The diversity of DNA sequencing methods and algorithms for genome assemblies presents scientists with a bewildering array of choices. Here, we construct and compare eight candidate assemblies combining overlapping shotgun read data, mate-pai
Externí odkaz:
https://doaj.org/article/f2ebfb266b534c02926db4712f6b97bb