Zobrazeno 1 - 10
of 178
pro vyhledávání: '"James O Lloyd-Smith"'
Autor:
Celine E Snedden, James O Lloyd-Smith
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012171 (2024)
Researchers and clinicians often rely on molecular assays like PCR to identify and monitor viral infections, instead of the resource-prohibitive gold standard of viral culture. However, it remains unclear when (if ever) PCR measurements of viral load
Externí odkaz:
https://doaj.org/article/dd06efd87753470cada59304b6fb744b
Autor:
Julia R Port, Dylan H Morris, Jade C Riopelle, Claude Kwe Yinda, Victoria A Avanzato, Myndi G Holbrook, Trenton Bushmaker, Jonathan E Schulz, Taylor A Saturday, Kent Barbian, Colin A Russell, Rose Perry-Gottschalk, Carl Shaia, Craig Martens, James O Lloyd-Smith, Robert J Fischer, Vincent J Munster
Publikováno v:
eLife, Vol 12 (2024)
It remains poorly understood how SARS-CoV-2 infection influences the physiological host factors important for aerosol transmission. We assessed breathing pattern, exhaled droplets, and infectious virus after infection with Alpha and Delta variants of
Externí odkaz:
https://doaj.org/article/4c84307fc85040989316830046220c70
Autor:
Seth Blumberg, Phoebe Lu, Ada T Kwan, Christopher M Hoover, James O Lloyd-Smith, David Sears, Stefano M Bertozzi, Lee Worden
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010308 (2022)
The explosive outbreaks of COVID-19 seen in congregate settings such as prisons and nursing homes, has highlighted a critical need for effective outbreak prevention and mitigation strategies for these settings. Here we consider how different types of
Externí odkaz:
https://doaj.org/article/77e19fd0aa2a4bf6bd950248515485c5
Autor:
Dylan H Morris, Kwe Claude Yinda, Amandine Gamble, Fernando W Rossine, Qishen Huang, Trenton Bushmaker, Robert J Fischer, M Jeremiah Matson, Neeltje Van Doremalen, Peter J Vikesland, Linsey C Marr, Vincent J Munster, James O Lloyd-Smith
Publikováno v:
eLife, Vol 10 (2021)
Ambient temperature and humidity strongly affect inactivation rates of enveloped viruses, but a mechanistic, quantitative theory of these effects has been elusive. We measure the stability of SARS-CoV-2 on an inert surface at nine temperature and hum
Externí odkaz:
https://doaj.org/article/35dd5c0a38174596b71449545300d491
Autor:
Renata L Muylaert, Ben Davidson, Alex Ngabirano, Gladys Kalema-Zikusoka, Hayley MacGregor, James O Lloyd-Smith, Ahmed Fayaz, Matthew A Knox, David T S Hayman
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0254467 (2021)
Cross-species transmission of pathogens is intimately linked to human and environmental health. With limited healthcare and challenging living conditions, people living in poverty may be particularly susceptible to endemic and emerging diseases. Simi
Externí odkaz:
https://doaj.org/article/bdf1558ca36f44799b98b31bea922974
Autor:
Tian-Hao Zhang, Lei Dai, John P Barton, Yushen Du, Yuxiang Tan, Wenwen Pang, Arup K Chakraborty, James O Lloyd-Smith, Ren Sun
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009009 (2020)
Drug-resistant mutations often have deleterious impacts on replication fitness, posing a fitness cost that can only be overcome by compensatory mutations. However, the role of fitness cost in the evolution of drug resistance has often been overlooked
Externí odkaz:
https://doaj.org/article/43fdf35ed5584d248be30a0da88b4e79
Autor:
Benny Borremans, Amandine Gamble, KC Prager, Sarah K Helman, Abby M McClain, Caitlin Cox, Van Savage, James O Lloyd-Smith
Publikováno v:
eLife, Vol 9 (2020)
Understanding and mitigating SARS-CoV-2 transmission hinges on antibody and viral RNA data that inform exposure and shedding, but extensive variation in assays, study group demographics and laboratory protocols across published studies confounds infe
Externí odkaz:
https://doaj.org/article/a6657acf4ab24508ad0aaa60188866a9
Autor:
K C Prager, Michael G Buhnerkempe, Denise J Greig, Anthony J Orr, Eric D Jensen, Forrest Gomez, Renee L Galloway, Qingzhong Wu, Frances M D Gulland, James O Lloyd-Smith
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008407 (2020)
Confronted with the challenge of understanding population-level processes, disease ecologists and epidemiologists often simplify quantitative data into distinct physiological states (e.g. susceptible, exposed, infected, recovered). However, data defi
Externí odkaz:
https://doaj.org/article/f7d07a0c335b4eaf80585d51ef0c2efc
Publikováno v:
eLife, Vol 9 (2020)
Traveller screening is being used to limit further spread of COVID-19 following its recent emergence, and symptom screening has become a ubiquitous tool in the global response. Previously, we developed a mathematical model to understand factors gover
Externí odkaz:
https://doaj.org/article/aa221989970741b28bcc4be9932cb435
Autor:
Katelyn M Gostic, Rebecca Bridge, Shane Brady, Cécile Viboud, Michael Worobey, James O Lloyd-Smith
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008109 (2019)
Across decades of co-circulation in humans, influenza A subtypes H1N1 and H3N2 have caused seasonal epidemics characterized by different age distributions of cases and mortality. H3N2 causes the majority of severe, clinically attended cases in high-r
Externí odkaz:
https://doaj.org/article/0911ed1c4d5d4c49a882af33190368c2