Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James O'Connor-Moneley"'
Autor:
James O'Connor-Moneley, Jessica Fletcher, Cody Bean, Josie Parker, Steven L Kelly, Gary P Moran, Derek J Sullivan
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308665 (2024)
Development of resistance and tolerance to antifungal drugs in Candida albicans can compromise treatment of infections caused by this pathogenic yeast species. The uniquely expanded C. albicans TLO gene family is comprised of 14 paralogous genes whic
Externí odkaz:
https://doaj.org/article/0ca5a5c4354540fcbe4ada98421973f4
Autor:
Jessica Fletcher, James O'Connor-Moneley, Dean Frawley, Peter R Flanagan, Leenah Alaalm, Pilar Menendez-Manjon, Samuel Vega Estevez, Shane Hendricks, Andrew L Woodruff, Alessia Buscaino, Matthew Z Anderson, Derek J Sullivan, Gary P Moran
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011082 (2023)
The Candida albicans genome contains between ten and fifteen distinct TLO genes that all encode a Med2 subunit of Mediator. In order to investigate the biological role of Med2/Tlo in C. albicans we deleted all fourteen TLO genes using CRISPR-Cas9 mut
Externí odkaz:
https://doaj.org/article/6874864e6b33490da8798f1d41d1bd22
Autor:
David E. McReynolds, Advan Moorthy, James O'Connor Moneley, Mary Ann Jabra‐Rizk, Ahmed S. Sultan
Publikováno v:
Journal of Prosthodontics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4929af401dba78399094f2972f1311eb
https://doi.org/10.1111/jopr.13687
https://doi.org/10.1111/jopr.13687
Publikováno v:
Essays in Biochemistry.
Mediator is a complex of polypeptides that plays a central role in the recruitment of RNA polymerase II to promoters and subsequent transcriptional activation in eukaryotic organisms. Studies have now shown that Mediator has a role in regulating expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc44222e6e7fa554a2a69a8272b39b57
https://doi.org/10.1042/ebc20220238
https://doi.org/10.1042/ebc20220238