Zobrazeno 1 - 10
of 12
pro vyhledávání: '"James N Sampayo"'
Autor:
John Gilbey, Eef Cauwelier, Mark W Coulson, Lee Stradmeyer, James N Sampayo, Anja Armstrong, Eric Verspoor, Laura Corrigan, Jonathan Shelley, Stuart Middlemas
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164327 (2016)
Understanding the habitat use patterns of migratory fish, such as Atlantic salmon (Salmo salar L.), and the natural and anthropogenic impacts on them, is aided by the ability to identify individuals to their stock of origin. Presented here are the re
Externí odkaz:
https://doaj.org/article/a025098f188946f7a330cc66a0354e80
Autor:
Salvatore DiMauro, Lee N. Benson, Gregory B. Wilson, D. Grahame Hardie, Claudio Bruno, James N Sampayo, Hasan O. Akman, Fiona A. Ross, Sara Shanske, John W. Scott
Publikováno v:
Pediatric Research. 62:499-504
A 10-wk-old infant girl with severe hypertrophy of the septal and atrial walls by cardiac ultrasound, developed progressive ventricular wall thickening and died of aspiration pneumonia at 5 mo of age. Postmortem examination revealed ventricular hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202398cb036a9013f37850a0ff32bcec
https://doi.org/10.1203/pdr.0b013e3181462b86
https://doi.org/10.1203/pdr.0b013e3181462b86
Publikováno v:
Aging Cell. 2:319-326
Summary The lifespan of Caenorhabditis elegans can be extendedby the administration of synthetic superoxide dismutase/catalase mimetics (SCMs) without any effects on develop-ment or fertility. Here we demonstrate that the mimetics,Euk-134 and Euk-8,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed549d2b3e60f0f4046d77102db3350a
https://doi.org/10.1046/j.1474-9728.2003.00063.x
https://doi.org/10.1046/j.1474-9728.2003.00063.x
Publikováno v:
Biochemical Society Transactions. 31:1305-1307
To date, more than 40 genes have been identified in the nematode Caenorhabditis elegans, which, when mutated, lead to an increase in lifespan. Of those tested, all confer an increased resistance to oxidative stress. In addition, the lifespan of C. el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d00e8dc34f1e672676623f07a57b2a
https://doi.org/10.1042/bst0311305
https://doi.org/10.1042/bst0311305
Autor:
Matthew S. Gill, Anders Olsen, Maithili C. Vantipalli, Mark P. White, Michael G. Benedetti, James N. Sampayo, Gordon J. Lithgow, Amanda L. Foster
Publikováno v:
Experimental gerontology. 43(10)
The observation that long-lived and relatively healthy animals can be obtained by simple genetic manipulation prompts the search for chemical compounds that have similar effects. Since aging is the most important risk factor for many socially and eco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6459d590f2fbf18daac85f03521e476b
https://pubmed.ncbi.nlm.nih.gov/18755260
https://pubmed.ncbi.nlm.nih.gov/18755260
Prompted by successful genetic interventions in aging we now consider the utility of pharmacological interventions. A few clear cases of lifespan extension resulting from exposure to compounds suggest that aging can be slowed and that the pharmacolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d73ce882ac8d4906a15db296632283
https://europepmc.org/articles/PMC3458493/
https://europepmc.org/articles/PMC3458493/
Autor:
Scott I. Hsieh, Hanh Hoang, Natalie Ann Rangel, James N. Sampayo, Yi-Ting Lin, Amanda L. Foster, Chandra Srinivasan, Gordon J. Lithgow
Publikováno v:
Free radical biologymedicine. 40(7)
Relative to iron and copper we know very little about the cellular roles of manganese. Some studies claim that manganese acts as a radical scavenger in unicellular organisms, while there have been other reports that manganese causes Parkinson's disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7810d9a80a02d5b80f96228953b0be02
https://pubmed.ncbi.nlm.nih.gov/16545686
https://pubmed.ncbi.nlm.nih.gov/16545686
Autor:
James N. Sampayo, Gordon J. Lithgow
Publikováno v:
Science of Aging Knowledge Environment. 2004
The accumulation of damage caused by reactive oxygen species (ROS) is held to be one of the underlying causes of age-related decline and has been shown to be involved in a number of pathological states. Inherent defense mechanisms have evolved to lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4f3032168384d2f0f109451f5d9972
https://doi.org/10.1126/sageke.2004.25.pe27
https://doi.org/10.1126/sageke.2004.25.pe27
Publikováno v:
Aalborg University
Many genetic or environmental manipulations that extend life span in the nematode Caenorhabditis elegans (C. elegans) also enhance survival following acute stresses such as oxidative damage and thermal stress. This coupling of stress response and agi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2f3d06996a23cec9a4b363aace2f22
https://pubmed.ncbi.nlm.nih.gov/12957648
https://pubmed.ncbi.nlm.nih.gov/12957648
Publikováno v:
Aging of Organisms ISBN: 9789048163328
Aalborg University
Aalborg University
In the last decade of the 20th century one model organism has received more attention from gerontologists than any other, namely the free-living soil nematode Caenorhabditis elegans (C. elegans). We owe much of our general view of the genetic determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577d45c3f0224470191e3a38e0c5e7de
https://doi.org/10.1007/978-94-017-0671-1_7
https://doi.org/10.1007/978-94-017-0671-1_7