Zobrazeno 1 - 10
of 109
pro vyhledávání: '"James N, MacLeod"'
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-21 (2022)
Abstract Background Bone marrow (BM)- and adipose tissue (AT)-derived mesenchymal stromal cells (MSCs) have shown potential as cell-based therapies for cartilage and bone injuries and are used increasingly in human and veterinary practice to facilita
Externí odkaz:
https://doaj.org/article/9e9404168e5d43368e36a6b7cab687da
Autor:
Bastian L. Gruber, Michael J. Mienaltowski, James N. MacLeod, Johannes Schittny, Stephanie Kasper, Martin Flück
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Objective Expression of the de-adhesive extracellular matrix protein tenascin-C (TNC) is associated with the early postnatal development of articular cartilage which is both load-dependent and associated with chondrocyte differentiation. We
Externí odkaz:
https://doaj.org/article/327ebe48b2b54772a48adeeb9d7f7fa3
Autor:
Bruno C. Menarim, Hossam El-Sheikh Ali, Shavahn C. Loux, Kirsten E. Scoggin, Theodore S. Kalbfleisch, James N. MacLeod, Linda A. Dahlgren
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Osteoarthritis (OA) may result from impaired ability of synovial macrophages to resolve joint inflammation. Increasing macrophage counts in inflamed joints through injection with bone marrow mononuclear cells (BMNC) induces lasting resolution of syno
Externí odkaz:
https://doaj.org/article/b73c1d66ac2345e682476502fe8b97ca
Autor:
Chan Hee Mok, James N. MacLeod
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Within developing synovial joints, interzone and anlagen cells progress through divergent chondrogenic pathways to generate stable articular cartilage and transient hypertrophic anlagen cartilage, respectively. Understanding the comparative cell biol
Externí odkaz:
https://doaj.org/article/56a864ac3daa4860bf8de3ed2afec096
Autor:
N. B. Kingsley, Natasha A. Hamilton, Gabriella Lindgren, Ludovic Orlando, Ernie Bailey, Samantha Brooks, Molly McCue, T. S. Kalbfleisch, James N. MacLeod, Jessica L. Petersen, Carrie J. Finno, Rebecca R. Bellone
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/c31f77bf2e564b59879736f3511dedcc
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Background: Bone marrow (BM)- and adipose tissue (AT)-derived mesenchymal stem cells (MSCs) are used increasingly for autologous cell therapy in equine practice to treat musculoskeletal and other injuries. Current recommendations often call for 10–
Externí odkaz:
https://doaj.org/article/376b4c014c1546a7af3704b75e72074a
Autor:
Robert J. Schaefer, Mikkel Schubert, Ernest Bailey, Danika L. Bannasch, Eric Barrey, Gila Kahila Bar-Gal, Gottfried Brem, Samantha A. Brooks, Ottmar Distl, Ruedi Fries, Carrie J. Finno, Vinzenz Gerber, Bianca Haase, Vidhya Jagannathan, Ted Kalbfleisch, Tosso Leeb, Gabriella Lindgren, Maria Susana Lopes, Núria Mach, Artur da Câmara Machado, James N. MacLeod, Annette McCoy, Julia Metzger, Cecilia Penedo, Sagi Polani, Stefan Rieder, Imke Tammen, Jens Tetens, Georg Thaller, Andrea Verini-Supplizi, Claire M. Wade, Barbara Wallner, Ludovic Orlando, James R. Mickelson, Molly E. McCue
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-18 (2017)
Abstract Background To date, genome-scale analyses in the domestic horse have been limited by suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of the current SNP genotyping arrays. The recent availability of whole g
Externí odkaz:
https://doaj.org/article/04b87937b039413b87f3bf369e812a52
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220728 (2019)
Gene-annotation enrichment is a common method for utilizing ontology-based annotations in gene and gene-product centric knowledgebases. Effective utilization of these annotations requires inferring semantic linkages by tracing paths through edges in
Externí odkaz:
https://doaj.org/article/3c4a13871fdd4e3d92d38ee506299a67
Autor:
Anna R. Dahlgren, Erica Y. Scott, Tamer Mansour, Erin N. Hales, Pablo J. Ross, Theodore S. Kalbfleisch, James N. MacLeod, Jessica L. Petersen, Rebecca R. Bellone, Carrie J. Finno
Publikováno v:
Non-Coding RNA, Vol 6, Iss 3, p 32 (2020)
Long non-coding RNAs (lncRNAs) are untranslated regulatory transcripts longer than 200 nucleotides that can play a role in transcriptional, post-translational, and epigenetic regulation. Traditionally, RNA-sequencing (RNA-seq) libraries have been cre
Externí odkaz:
https://doaj.org/article/72db4a549f764aac83aa2139fc04b8b4
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201554 (2018)
Genomic variants in both coding and non-coding sequences can have functionally important and sometimes deleterious effects on exon splicing of gene transcripts. For transcriptome profiling using RNA-seq, the accurate alignment of reads across exon ju
Externí odkaz:
https://doaj.org/article/db4968b03826407cb8865bc719094dd2