Zobrazeno 1 - 10
of 107
pro vyhledávání: '"James N, Herron"'
Autor:
Darrell R. Galloway, Jiahui Li, Nguyen X. Nguyen, Frank W. Falkenberg, Lisa Henning, Robert Krile, Ying-Liang Chou, James N. Herron, J. Scott Hale, E. Diane Williamson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
This study evaluated a depot-formulated cytokine-based adjuvant to improve the efficacy of the recombinant F1V (rF1V) plague vaccine and examined the protective response following aerosol challenge in a murine model. The results of this study showed
Externí odkaz:
https://doaj.org/article/11996e242cf74db8938ba29f3837f5e6
Autor:
Darrell R. Galloway, Nguyen X. Nguyen, Jiahui Li, Nicholas Houston, Gage Gregersen, E. Diane Williamson, Frank W. Falkenberg, James N. Herron, J. Scott Hale
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The development of a safe and effective vaccine against Yersinia pestis, the causative organism for plague disease, remains an important global health priority. Studies have demonstrated effective immune-based protection against plague challenge that
Externí odkaz:
https://doaj.org/article/ebb1d69466164a35bf18640b33a8c32e
Autor:
Paul J. Shami, Imit Kaur, Ken M. Kosak, Moises Terrazas, Kenneth M. Boucher, Steven E. Kern, James N. Herron
Publikováno v:
Pharmaceutical Research. 32:1395-1406
O(2)-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] or JS-K is a nitric oxide-producing prodrug of the arylated diazeniumdiolate class with promising anti-tumor activity. JS-K has challenging solubility and stability
Publikováno v:
Journal of Pharmaceutical Sciences. 97:2080-2090
A rapid-throughput screening assay was developed to estimate the salt solubility parameter, K(SP), with a minimal quantity of drug. This assay allows for early evaluation of salt limited solubility with a large number of counter-ions and biologically
Publikováno v:
Nanotechnology. 15:1368-1374
We describe the basis for an affinity biosensor platform in which enhanced fluorescence transduction occurs through the optical excitation of molecules located within metallic nanocavities. These nanocavities are about 200 nm in diameter, are arrange
Proteins are still gaining importance in the pharmaceutical world, where they are used to improve our arsenal of therapeutic drugs and vaccines and as diagnostic tools. Proteins are different from'traditional'low-molecular-weight drugs. As a group, t
Single-chain polymorphism analysis in long QT syndrome using planar waveguide fluorescent biosensors
Publikováno v:
Analytical Biochemistry. 315:223-237
Rapid detection of single nucleotide polymorphisms (SNPs) has potential applications in both genetic screening and pharmacogenomics. Planar waveguide fluorescent biosensor technology was employed to detect SNPs using a simple hybridization assay with
Publikováno v:
Pharmaceutical Research. 20:591-596
Purpose. This work examines the effectiveness of synthetic peptide immunogens derived from immunodominant T-cell epitopes as replacements for their intact parent protein in vaccines.
Autor:
James N. Herron, E. A. A. M. Vernooij, C. Gentry, J. J. Kettenes-van den Bosch, Daan J.A. Crommelin
Publikováno v:
Pharmaceutical Research. 16:1658-1661
Autor:
Nicole L. W. Van Hal, G.A.M.S. (Guus) van Dongen, Ruud H. Brakenhoff, C. B. M. Ten Brink, James N. Herron, Gordon B. Snow
Publikováno v:
Van Hal, N L W, Van Dongen, G A M S, Ten Brink, C B M, Herron, J N, Snow, G B & Brakenhoff, R H 1997, ' Sequence variation in the monoclonal-antibody-U36-defined CD44v6 epitope ', Cancer Immunology Immunotherapy, vol. 45, no. 2, pp. 88-92 . https://doi.org/10.1007/s002620050406
Cancer Immunology Immunotherapy, 45(2), 88-92. Springer Science and Business Media Deutschland GmbH
Cancer Immunology Immunotherapy, 45(2), 88-92. Springer Science and Business Media Deutschland GmbH
Monoclonal antibody (mAb) U36 was developed for the treatment of minimal residual disease of head and neck squamous cell carcinoma (HNSCC). The mAb- U36-defined antigen was characterized by cDNA cloning, and was shown to be identical to the keratinoc