Zobrazeno 1 - 10
of 63
pro vyhledávání: '"James Monkman"'
Autor:
Habib Sadeghirad, James Monkman, Chin Wee Tan, Ning Liu, Joseph Yunis, Meg L. Donovan, Afshin Moradi, Niyati Jhaveri, Chris Perry, Mark N. Adams, Ken O’Byrne, Majid E. Warkiani, Rahul Ladwa, Brett G.M. Hughes, Arutha Kulasinghe
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) generally has a poor prognosis for patients with limited treatment options. While incorporating immune checkpoint inhibitors (ICIs) has now become the standard
Externí odkaz:
https://doaj.org/article/f1dddeab14594adbaeaca19710053a73
Autor:
Meg L. Donovan, Niyati Jhaveri, Ning Ma, Bassem Ben Cheikh, James DeRosa, Ritu Mihani, Naomi Berrell, Jacky Y. Suen, James Monkman, John F. Fraser, Arutha Kulasinghe
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103226- (2024)
Summary: Single-cell spatial analysis of proteins is rapidly becoming increasingly important in revealing biological insights. Here, we present a protocol for automated high-plex multi-slide immunofluorescence staining and imaging of human head and n
Externí odkaz:
https://doaj.org/article/9a7d9e6b475d40c5a49c94dd441e8ff5
Autor:
James Monkman, Afshin Moradi, Joseph Yunis, Geoff Ivison, Aaron Mayer, Rahul Ladwa, Ken O’Byrne, Arutha Kulasinghe
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract The spatial localisation of immune cells within tumours are key to understand the intercellular communications that can dictate clinical outcomes. Here, we demonstrate an analysis pipeline for highly multiplexed CODEX data to phenotype and p
Externí odkaz:
https://doaj.org/article/5f104c6fa000442e8647ba9dd819e301
Autor:
Chin Wee Tan, Jinjin Chen, Ning Liu, Dharmesh D. Bhuva, Tony Blick, James Monkman, Caroline Cooper, Malvika Kharbanda, Kristen Feher, Belinda Phipson, Emily E. Killingbeck, Liuliu Pan, Youngmi Kim, Yan Liang, Andy Nam, Michael Leon, Paulo Souza-Fonseca-Guimaraes, Seigo Nagashima, Ana Paula Camargo Martins, Cleber Machado-Souza, Lucia de Noronha, Benjamin Tang, Kirsty Short, John Fraser, Gabrielle T. Belz, Fernando Souza-Fonseca-Guimaraes, Arutha Kulasinghe, Melissa J. Davis
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105016- (2024)
Summary: The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages to have elevated expression of IFI27 in areas of infection.
Externí odkaz:
https://doaj.org/article/4f2fdb2f06f84144987d21c5de056820
Autor:
Vahid Yaghoubi Naei, James Monkman, Habib Sadeghirad, Ahmed Mehdi, Tony Blick, William Mullally, Ken O'Byrne, Majid Ebrahimi Warkiani, Arutha Kulasinghe
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Objectives Non‐small‐cell lung carcinoma (NSCLC) is the most prevalent and lethal form of lung cancer. The need for biomarker‐informed stratification of targeted therapies has underpinned the need to uncover the underlying properties o
Externí odkaz:
https://doaj.org/article/71afaa1369b246e48af2b950a8616b55
Autor:
Nataly Stylianou, Ismail Sebina, Nicholas Matigian, James Monkman, Hadeel Doehler, Joan Röhl, Mark Allenby, Andy Nam, Liuliu Pan, Anja Rockstroh, Habib Sadeghirad, Kimberly Chung, Thais Sobanski, Ken O'Byrne, Ana Clara Simoes Florido Almeida, Patricia Zadorosnei Rebutini, Cleber Machado‐Souza, Emanuele Therezinha Schueda Stonoga, Majid E Warkiani, Carlos Salomon, Kirsty Short, Lana McClements, Lucia deNoronha, Ruby Huang, Gabrielle T Belz, Fernando Souza‐Fonseca‐Guimaraes, Vicki Clifton, Arutha Kulasinghe
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 2, Pp n/a-n/a (2024)
Abstract Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus infection in pregnancy is associated with higher incidence of placental dysfunction, referred to by a few studies as a ‘preeclampsia‐like syndrome’. Howe
Externí odkaz:
https://doaj.org/article/c26444dbfdab4c58aeeef3df629fe26a
Autor:
Arutha Kulasinghe, Najiba Mammadova, James Monkman, Dmytro Klymyshyn, Niyati Jhaveri, Bassem Ben Cheikh, Aditya Pratapa, Nadine Nelson, Michael Prater
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a7b2a8db66274d72b84f2c77e6b8a6fe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b2742b7e6b8b49ebaf2dde19b053de16
Autor:
Habib Sadeghirad, Ning Liu, James Monkman, Ning Ma, Bassem Ben Cheikh, Niyati Jhaveri, Chin Wee Tan, Majid Ebrahimi Warkiani, Mark N. Adams, Quan Nguyen, Rahul Ladwa, Oliver Braubach, Ken O’Byrne, Melissa Davis, Brett G. M. Hughes, Arutha Kulasinghe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Mucosal head and neck squamous cell carcinoma (HNSCC) are the seventh most common cancer, with approximately 50% of patients living beyond 5 years. Immune checkpoint inhibitors (ICIs) have shown promising results in patients with recurrent or metasta
Externí odkaz:
https://doaj.org/article/deb6e95791cc45ce81a3059cd2e13bb7
Autor:
Maryam Shojaei, Amir Shamshirian, James Monkman, Laura Grice, Minh Tran, Chin Wee Tan, Siok Min Teo, Gustavo Rodrigues Rossi, Timothy R. McCulloch, Marek Nalos, Maedeh Raei, Alireza Razavi, Roya Ghasemian, Mobina Gheibi, Fatemeh Roozbeh, Peter D. Sly, Kirsten M. Spann, Keng Yih Chew, Yanshan Zhu, Yao Xia, Timothy J. Wells, Alexandra Cristina Senegaglia, Carmen Lúcia Kuniyoshi, Claudio Luciano Franck, Anna Flavia Ribeiro dos Santos, Lucia de Noronha, Sepideh Motamen, Reza Valadan, Omolbanin Amjadi, Rajan Gogna, Esha Madan, Reza Alizadeh-Navaei, Liliana Lamperti, Felipe Zuñiga, Estefania Nova-Lamperti, Gonzalo Labarca, Ben Knippenberg, Velma Herwanto, Ya Wang, Amy Phu, Tracy Chew, Timothy Kwan, Karan Kim, Sally Teoh, Tiana M. Pelaia, Win Sen Kuan, Yvette Jee, Jon Iredell, Ken O’Byrne, John F. Fraser, Melissa J. Davis, Gabrielle T. Belz, Majid E. Warkiani, Carlos Salomon Gallo, Fernando Souza-Fonseca-Guimaraes, Quan Nguyen, Anthony Mclean, Arutha Kulasinghe, Kirsty R. Short, Benjamin Tang
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
PurposeRobust biomarkers that predict disease outcomes amongst COVID-19 patients are necessary for both patient triage and resource prioritisation. Numerous candidate biomarkers have been proposed for COVID-19. However, at present, there is no consen
Externí odkaz:
https://doaj.org/article/90cb309064c14456837451531198b0a2