Zobrazeno 1 - 10
of 73
pro vyhledávání: '"James Meehan"'
Autor:
Chris Cousens, James Meehan, David Collie, Steven Wright, Ziyuan Chang, Helen Todd, Jo Moore, Lynn Grant, Carola R. Daniel, Peter Tennant, Adrian Ritchie, James Nixon, Chris Proudfoot, Stefano Guido, Helen Brown, Calum D. Gray, Tom J. MacGillivray, R. Eddie Clutton, Stephen N. Greenhalgh, Rachael Gregson, David J. Griffiths, James Spivey, Nicole Storer, Chad E. Eckert, Mark Gray
Publikováno v:
Genes, Vol 15, Iss 8, p 1019 (2024)
Ovine pulmonary adenocarcinoma (OPA) is an infectious, neoplastic lung disease of sheep that causes significant animal welfare and economic issues throughout the world. Understanding OPA pathogenesis is key to developing tools to control its impact.
Externí odkaz:
https://doaj.org/article/2ef347c0ba64400ab9d9f5abc6eb3056
Autor:
James Meehan, Mark Gray
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 6, p 549 (2024)
In 2022, there was an estimated incidence of 20 million cancer cases and 9 [...]
Externí odkaz:
https://doaj.org/article/f82be9f1f2b34a71ab37c3e376e0728b
Autor:
Carol Ward, James Meehan, Mark E Gray, Alan F Murray, David J Argyle, Ian H Kunkler, Simon P Langdon
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 2, Pp 71-100 (2020)
Dysregulation of cellular pH is frequent in solid tumours and provides potential opportunities for therapeutic intervention. The acidic microenvironment within a tumour can promote migration, invasion and metastasis of cancer cells through a variety
Externí odkaz:
https://doaj.org/article/433acbca338740a690220966460cdf67
Autor:
Mark Gray, Arran K. Turnbull, Carol Ward, James Meehan, Carlos Martínez-Pérez, Maria Bonello, Lisa Y. Pang, Simon P. Langdon, Ian H. Kunkler, Alan Murray, David Argyle
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-19 (2019)
Abstract Background Radiotherapy plays an important role in the multimodal treatment of breast cancer. The response of a breast tumour to radiation depends not only on its innate radiosensitivity but also on tumour repopulation by cells that have dev
Externí odkaz:
https://doaj.org/article/f86ee81a892849e88ed5db0ce297194d
Autor:
Edward J. Jarman, Carol Ward, Arran K. Turnbull, Carlos Martinez-Perez, James Meehan, Chrysi Xintaropoulou, Andrew H. Sims, Simon P. Langdon
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-18 (2019)
Abstract Background Tumour hypoxia is a driver of breast cancer progression associated with worse prognosis and more aggressive disease. The cellular response to hypoxia is mediated by the hypoxia-inducible transcription factors HIF-1 and HIF-2, whos
Externí odkaz:
https://doaj.org/article/923a851c858a45a7b0788fc90b57314e
Autor:
James Meehan
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 4, p 585 (2022)
While the term biomarker is thought to have first been used in the 1970s, the concept itself is considered to be much older [...]
Externí odkaz:
https://doaj.org/article/a4788f2487a04fea97bec060dcb43854
Autor:
Mark Gray, Arran K. Turnbull, James Meehan, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, David J. Argyle
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/a79dd117347a4adc9ac16f07111d04e5
Autor:
Mark Gray, James Meehan, Arran K. Turnbull, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, David J. Argyle
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Treating individual patients on the basis of specific factors, such as biomarkers, molecular signatures, phenotypes, environment, and lifestyle is what differentiates the precision medicine initiative from standard treatment regimens. Although precis
Externí odkaz:
https://doaj.org/article/6e073301f12f42c398ad3721d64f089b
Autor:
Mark Gray, Arran K. Turnbull, James Meehan, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, David J. Argyle
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Research using in vitro canine mammary cancer cell lines and naturally-occurring canine mammary tumors are not only fundamental models used to advance the understanding of cancer in veterinary patients, but are also regarded as excellent translationa
Externí odkaz:
https://doaj.org/article/03478e29514d401a9b66e422bfe6cb16
Autor:
Mark Gray, James Meehan, Carlos Martínez-Pérez, Charlene Kay, Arran K. Turnbull, Linda R. Morrison, Lisa Y. Pang, David Argyle
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Despite extensive research over many decades, human breast cancer remains a major worldwide health concern. Advances in pre-clinical and clinical research has led to significant improvements in recent years in how we manage breast cancer patients. Al
Externí odkaz:
https://doaj.org/article/45c6cc0aec4d4be6b4e8d351cf46508a