Zobrazeno 1 - 10
of 76
pro vyhledávání: '"James Mccloskey"'
Autor:
Rupa Narayan, Ana Alfonso Piérola, William B. Donnellan, Antonieta Molero Yordi, Maher Abdul‐Hay, Uwe Platzbecker, Marion Subklewe, Tapan Mahendra Kadia, Juan Manuel Alonso‐Domínguez, James McCloskey, Kathryn Bradford, Martin Curtis, Nikki Daskalakis, Christina Guttke, Karim Safer, Brett Hiebert, Joseph Murphy, Xiang Li, Ken Duchin, Daniel Esteban
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Relapsed/refractory (r/r) acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) outcomes remain poor. A targeted cluster of differentiation (CD)33 × CD3 bispecific antibody, JNJ‐67571244, was assessed to identify the maximum tol
Externí odkaz:
https://doaj.org/article/274473cdc5184c6596ff63a5c9aab2bf
Autor:
Elias Jabbour, Hagop Kantarjian, Ibrahim Aldoss, Pau Montesinos, Jessica Leonard, David Gomez, Maria Baer, Carlo Gambacorti-Passerini, James Mccloskey, Yosuke Minami, Cristina Papayannidis, Vanderson Rocha, Philippe Rousselot, Pankit Vachhani, Eunice Wang, Meliessa Hennessy, Niti Patel, Alexander Vorog, Bingxia Wang, Huilan Yao, Tammie Yeh, Josep Maria Ribera
Publikováno v:
HemaSphere, Vol 7, p e68516d0 (2023)
Externí odkaz:
https://doaj.org/article/f833a33b51b945e094c5af6cc6ac5e78
Autor:
Jorge Cortes, Michael Deininger, Elza Lomaia, Beatriz Moiraghi, Soledad Undurraga, Carolina Pavlovsky, Charles Chuah, Tomasz Sacha, Jeffrey H. Lipton, James Mccloskey, Philippe Rousselot, Gianantonio Rosti, Hugues de Lavallade, Christine Rojas, Anna Turkina, Moshe Talpaz, Michael Mauro, Vickie Lu, Alexander Vorog, Jane Apperley
Publikováno v:
HemaSphere, Vol 7, p e85501cf (2023)
Externí odkaz:
https://doaj.org/article/f0b8d7a160ec4ce1b84d936813ace846
Autor:
Firas El Chaer, Lindsay Rein, Kazuya Shimoda, Junichiro Yuda, Tamanna Haque, James Mccloskey, Akiyoshi Takami, Masafumi Fukaya, Shuichi Shirane, Sujan Kabir, Jian Mei, Zhonggai LI, Mark Wade, Claudia Lebedinsky, Raajit K Rampal
Publikováno v:
HemaSphere, Vol 7, p e42358df (2023)
Externí odkaz:
https://doaj.org/article/ef0764327e2144cb9246525a9d8831ba
Autor:
Maher Albitar, Hong Zhang, Ahmad Charifa, Andrew Ip, Wanlong Ma, James McCloskey, Michele Donato, David Siegel, Stanley Waintraub, Martin Gutierrez, Andrew Pecora, Andre Goy
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e16261- (2023)
Current use of liquid biopsy is based on cell-free DNA (cfDNA) and the evaluation of mutations or methylation pattern. However, expressed RNA can capture mutations, changes in expression levels due to methylation, and provide information on cell of o
Externí odkaz:
https://doaj.org/article/0a7c0939ee8641638d0e567ca020ccb3
Autor:
Nicolas Boissel, Patrice Chevallier, Vadim Doronin, Laimonas Griskevicius, Alexey Maschan, James McCloskey, Alessandro Rambaldi, Giuseppe Rossi, Andrey Sokolov, Ulla Wartiovaara‐Kautto, Corina Oprea, Giovanni Abbadessa, Alice Gosselin, Sandrine Macé, Xavier Thomas
Publikováno v:
Cancer Medicine, Vol 11, Iss 5, Pp 1292-1298 (2022)
Abstract The poor prognosis of acute T‐cell lymphoblastic leukemia (T‐ALL) and T‐cell lymphoblastic lymphoma (T‐LBL) in older adults and patients with relapsed/refractory illness is an unmet clinical need, as there is no defined standard of c
Externí odkaz:
https://doaj.org/article/8eb438a3278541aab472cb141756c479
Autor:
Victor Bolbot, Gerasimos Theotokatos, James McCloskey, Dracos Vassalos, Evangelos Boulougouris, Bernard Twomey
Publikováno v:
International Journal of Naval Architecture and Ocean Engineering, Vol 14, Iss , Pp 100457- (2022)
The autonomous ships’ introduction is associated with a number of challenges including the lack of appropriate risk acceptance criteria to support the risk assessment process during the initial design phases. This study aims to develop a rational m
Externí odkaz:
https://doaj.org/article/5c683eac291a419c8cd830c26fc78d7a
Autor:
Hong Zhang, Muhammad A. Qureshi, Mohsin Wahid, Ahmad Charifa, Aamir Ehsan, Andrew Ip, Ivan De Dios, Wanlong Ma, Ipsa Sharma, James McCloskey, Michele Donato, David Siegel, Martin Gutierrez, Andrew Pecora, Andre Goy, Maher Albitar
Publikováno v:
The American Journal of Pathology. 193:51-59
Diagnosis and classification of tumors is increasingly dependent on biomarkers. RNA expression profiling using next-generation sequencing provides reliable and reproducible information on the biology of cancer. This study investigated targeted transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efcd4eb3701a12fa7db89e89905830f
https://doi.org/10.1016/j.ajpath.2022.09.006
https://doi.org/10.1016/j.ajpath.2022.09.006
Autor:
Naval Daver, Alexander E. Perl, Joseph Maly, Mark Levis, Ellen Ritchie, Mark Litzow, James McCloskey, Catherine C. Smith, Gary Schiller, Terrence Bradley, Ramon V. Tiu, Kiran Naqvi, Monique Dail, Deanna Brackman, Satya Siddani, Jing Wang, Brenda Chyla, Paul Lee, Jessica K. Altman
Publikováno v:
Journal of Clinical Oncology. 40:4048-4059
PURPOSE The FMS-related tyrosine kinase 3 (FLT3) inhibitor gilteritinib is standard therapy for relapsed/refractory FLT3-mutated ( FLT3 mut) acute myeloid leukemia (AML) but seldom reduces FLT3 mut burden or induces sustained efficacy. Gilteritinib c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d971be25ac6f7504f1727fdeb5b92e
https://doi.org/10.1200/jco.22.00602
https://doi.org/10.1200/jco.22.00602
Autor:
Jorge E. Cortes, Geoffrey Chan, Ashleigh O'Connell, Mirjana Zeremski, A. Douglas Laird, M. Naveed Shaik, Weidong Wendy Ma, Hagop M. Kantarjian, James McCloskey, Jeffrey Lancet, Mark A. Schroeder, Vivian G. Oehler, Wendy Stock, Daniel A. Pollyea, Michael R. Savona
Purpose: This open-label, multicenter, dose-finding, phase Ib study (NCT01546038) evaluated the safety, pharmacokinetics, pharmacodynamics, and clinical activity of the novel Hedgehog pathway Smoothened inhibitor glasdegib (PF-04449913) in patients (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe667682407264cca4df8cd19f3fd28
https://doi.org/10.1158/1078-0432.c.6525722.v1
https://doi.org/10.1158/1078-0432.c.6525722.v1
