Zobrazeno 1 - 10
of 10
pro vyhledávání: '"James McGuiness"'
Autor:
John A Ligon, Paul Castillo, Christina Von Roemeling, Natalie Silver, Frances Weidert, Adam Grippin, Jonathan Chardon-Robles, Eugene Hwang, Hector Mendez-Gomez, Study Staff, Elias Sayour, Sadeem Qdaisat, Dingpeng Zhang, James McGuiness, Nagheme Thomas, Anna Devries, Aida Karachi, Jianping Huang, Maryam Rahman, Elizabeth Ogando-Rivas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ff4cba9d8a244bf78c4d8b10af09b189
Autor:
Hector Mendez-Gomez, Anna DeVries, Brian Stover, Dingpeng Zhang, Adam Grippin, Christina Von Roemeling, Frances Weidert, Aida Karachi, Sadeem Qdaisat, Nagheme Thomas, James McGuiness, Paul Castillo, Jianping Huang, John Ligon, Natalie Silver, Patrick Kellish, Andria Doty, Sheila Carrera-Justiz, Michael Prados, Sabine Mueller, Maryam Rahman, Ashley Ghiaseddin, Duane Mitchell, Elias Sayour
Publikováno v:
Neuro-Oncology. 24:vii66-vii67
BACKGROUND Although mRNA vaccines have been deployed with great success against COVID-19, unlocking this technology against glioblastoma will necessitate new lipid-nanoparticle formulations that overcome cancer tolerance and immunosuppression. OBJECT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a81bcb22d5bfdb25ef7ac564da69419
https://doi.org/10.1093/neuonc/noac209.260
https://doi.org/10.1093/neuonc/noac209.260
Autor:
Duane Mitchell, Brandon Wummer, Adam J Grippin, Héctor R. Méndez-Gómez, James McGuiness, Sadeem Qdaisat, Elias Sayour, Kyle Dyson
Publikováno v:
Journal of Neuro-Oncology. 151:29-39
Brain tumors remain especially challenging to treat due to the presence of the blood–brain barrier. The unique biophysical properties of nanomaterials enable access to the tumor environment with minimally invasive injection methods such as intranas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de10d787c07d25587554a582c00dffb5
https://doi.org/10.1007/s11060-020-03559-9
https://doi.org/10.1007/s11060-020-03559-9
Autor:
James McGuiness, Frances Weidert, Dingpeng Zhang, Adam Grippin, Aida Karachi, Sadeem Qdaisat, Nagheme Thomas, Paul Castillo, Jianping Huang, John Ligon, Natalie Silver, Maryam Rahman, Eugene Hwang, Duane Mitchell, Hector Mendez-Gomez, Elias Sayour
Publikováno v:
Neuro-Oncology. 24:vii219-vii219
BACKGROUND Diffuse Intrinsic Pontine Glioma (DIPG) is uniformly fatal. Upon diagnosis, DIPG cannot be safely debulked and systemic therapies have unproven benefit. Immunotherapy can overcome these obstacles, but objective responses are rare; and canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9763876ac137fa69ea00c9085f5b48
https://doi.org/10.1093/neuonc/noac209.844
https://doi.org/10.1093/neuonc/noac209.844
Autor:
Adam Grippin, Sheila Carrera-Justiz, Frances Weidert, Héctor R. Méndez-Gómez, James McGuiness, Duane Mitchell, Elias J Sayour
Publikováno v:
Neuro Oncol
Background: Since the preponderance of pediatric gliomas are mutationally 'bland,' immune checkpoint inhibitors are unlikely to mediate therapeutic benefit. Alternately, immunologic response can be induced de novo against pediatric gliomas with mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9563714f6090e63705f6cf7a66cfeef5
https://europepmc.org/articles/PMC8168272/
https://europepmc.org/articles/PMC8168272/
Autor:
James McGuiness, Frances Weidert, Sheila Carrera-Justiz, Duane Mitchell, Adam Grippin, Elias Sayour, Héctor R. Méndez-Gómez
Publikováno v:
Neuro-Oncology
Background Since the preponderance of pediatric gliomas are mutationally ‘bland,’ immune checkpoint inhibitors are unlikely to mediate therapeutic benefit. Alternately, immunologic response can be induced de novo against pediatric gliomas with mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ec487a95f14fe49e65a798c5f9270f
http://europepmc.org/articles/PMC8168117
http://europepmc.org/articles/PMC8168117
Autor:
Adam J, Grippin, Kyle A, Dyson, Sadeem, Qdaisat, James, McGuiness, Brandon, Wummer, Duane A, Mitchell, Hector R, Mendez-Gomez, Elias J, Sayour
Publikováno v:
Journal of neuro-oncology. 151(1)
Brain tumors remain especially challenging to treat due to the presence of the blood-brain barrier. The unique biophysical properties of nanomaterials enable access to the tumor environment with minimally invasive injection methods such as intranasal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bd4f3eb72b87fb631b347d5d239b967
https://pubmed.ncbi.nlm.nih.gov/32757093
https://pubmed.ncbi.nlm.nih.gov/32757093
Autor:
Sheila Carrera-Justiz, Bikash Sahay, Elias Sayour, Duane Mitchell, Frances Weidert, James McGuiness, Héctor R. Méndez-Gómez, Loic P. Deleyrolle, Adam Grippin, Sridharan Gururangan, Brian Stover
BACKGROUND: Pediatric brain tumors are poorly immunogenic preventing current immunotherapies (i.e. checkpoint blockers) from having significant activity. Unlocking immunotherapy against these malignancies is predicated on reprogramming their immunoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d61dc7d66907b988ff34db92728cde
https://europepmc.org/articles/PMC6477442/
https://europepmc.org/articles/PMC6477442/
Autor:
Héctor R. Méndez-Gómez, Brian Stover, Elias Sayour, Frances Weidert, James McGuiness, Duane Mitchell
BACKGROUND: Diffuse Intrinsic Pontine Glioma (DIPG) remains uniformly recalcitrant and thus necessitates development of novel targeted therapies. The histone mutation in H3K27M is conserved in the preponderance of DIPG patients and may be exploited a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565e1dd6705b566ae3b7d3e584d06e4b
https://europepmc.org/articles/PMC6477280/
https://europepmc.org/articles/PMC6477280/
Autor:
Benjamin Griffith, James McGuiness, Brent A. Reynolds, Loic P. Deleyrolle, Colby L. Skinner, Christopher D. Louviere, Regina T. Martuscello, Hunter S. Futch
Application of toxic compounds used at maximum tolerated dose until resistance develops is the most commonly experienced outcome in cancer therapy. Based on successful concepts borrowed from the field of ecology to manage pest populations, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbb7121b42752346ce02d51646f4a1f
https://europepmc.org/articles/PMC4218110/
https://europepmc.org/articles/PMC4218110/