Zobrazeno 1 - 5
of 5
pro vyhledávání: '"James McCol"'
Autor:
Sriram Vijayraghavan, Thomas Blouin, James McCollum, Latarsha Porcher, François Virard, Jiri Zavadil, Carol Feghali-Bostwick, Natalie Saini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Systemic sclerosis is a connective tissue disorder characterized by excessive fibrosis that primarily affects women, and can present as a multisystem pathology. Roughly 4-22% of patients with systemic sclerosis develop cancer, which drastica
Externí odkaz:
https://doaj.org/article/9922427373d4473b9e26d8079f0b5aff
Autor:
Edward Jenkins, Markus Körbel, Caitlin O’Brien-Ball, James McColl, Kevin Y. Chen, Mateusz Kotowski, Jane Humphrey, Anna H. Lippert, Heather Brouwer, Ana Mafalda Santos, Steven F. Lee, Simon J. Davis, David Klenerman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
T cells can use TCR on microvilli to interact with peptide-MHC (pMHC) complexes on antigen presenting cells. Here the authors characterise how T cells use microvilli to interrogate reconstituted membranes for pMHC complexes and how this is regulated
Externí odkaz:
https://doaj.org/article/e163cebf0d034cc0b49fca7e959be290
Autor:
Laura Weimann, Kristina A Ganzinger, James McColl, Kate L Irvine, Simon J Davis, Nicholas J Gay, Clare E Bryant, David Klenerman
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64287 (2013)
Single-particle tracking (SPT) is widely used to study processes from membrane receptor organization to the dynamics of RNAs in living cells. While single-dye labeling strategies have the benefit of being minimally invasive, this comes at the expense
Externí odkaz:
https://doaj.org/article/4320fa141aa94701811e0dd120cf10e0
Autor:
David Lando, Ulrike Endesfelder, Harald Berger, Lakxmi Subramanian, Paul D. Dunne, James McColl, David Klenerman, Antony M. Carr, Markus Sauer, Robin C. Allshire, Mike Heilemann, Ernest D. Laue
Publikováno v:
Open Biology, Vol 2, Iss 7 (2012)
The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To understand the process of epigenetic inheritance, or propagation of histones and histone variants, as
Externí odkaz:
https://doaj.org/article/d4434d82101348dfb7371e24d1b3bdca
Autor:
James McCol, Dave Klenerman, Ji-Eun Lee, Steven F. Lee, Simon J. Davis, Ana Filipa L.O.M. Santos, Aleks Ponjavic, Alexander R. Carr
Publikováno v:
Biophysical Journal. 110:485a
Most optical imaging of individual cells has been conducted in 2D on flat glass or culture plastic. Not only is this very abstract from the biological environment and does not imitate physiological conditions, but it may lead to unwanted perturbation