Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James M. You"'
Autor:
Javier Octavio Mejía-Hernández, Simon P. Keam, Reem Saleh, Fenella Muntz, Stephen B. Fox, David Byrne, Arielle Kogan, Lokman Pang, Jennifer Huynh, Cassandra Litchfield, Franco Caramia, Guillermina Lozano, Hua He, James M. You, Shahneen Sandhu, Scott G. Williams, Ygal Haupt, Sue Haupt
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-17 (2022)
Abstract Understanding prostate cancer onset and progression in order to rationally treat this disease has been critically limited by a dire lack of relevant pre-clinical animal models. We have generated a set of genetically engineered mice that mimi
Externí odkaz:
https://doaj.org/article/72de5aef0f664a85b0c01a44bc290580
Autor:
Leng Han, Motao Zhu, Changsheng Xing, Yubin Zhou, Jingrong Mao, Xiao Yu, James M. You, Helen Yicheng Wang, Lixia Diao, Peng Tan, Rongfu Wang, Lian He
Publikováno v:
J Clin Invest
Beclin 1 (Becn1) is a key molecule in the autophagy pathway and has been implicated in cancer development. Due to the embryonic lethality of homozygous Becn1-deficient mice, the precise mechanisms and cell type-specific roles of Becn1 in regulating i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a0088d07d7f0cad7b2e088bffa679e
https://pubmed.ncbi.nlm.nih.gov/31657787
https://pubmed.ncbi.nlm.nih.gov/31657787
Autor:
Melissa Kennedy, Larry Glass, Daniel G. Glaze, Steve Kaminsky, Alan K. Percy, Jeffrey L. Neul, Nancy E. Jones, Daniela Tropea, Joseph P. Horrigan, Paige Nues, Kathie M. Bishop, James M. Youakim
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Rett syndrome (RTT) is rare neurodevelopmental disorder caused by mutations in the MECP2 gene that encodes methyl-CpG-binding protein 2 (MeCP2), a DNA-binding protein with roles in epigenetic regulation of gene expression. Functional loss of MeCP2 re
Externí odkaz:
https://doaj.org/article/b550d1b8d2c644c1ba103860350a3bb0
Autor:
Robert Manning, Daniel Ditzel Santos, Zachary R. Hunter, Allen W. Ho, Evdoxia Hatjiharissi, Kenneth C. Anderson, Xavier Leleu, Mariana Chemaly, Steven P. Treon, Yu-Tzu Tai, Christopher J. Patterson, Lian Xu, Nikhil C. Munshi, Jeffery L. Kutok, Olivier Tournilhac, Kelly O’Connor, Andrew R. Branagan, James M. You
Publikováno v:
Blood. 106:980-980
INTRODUCTION: In previous studies, we demonstrated that mast cells (MCs) may support the growth and survival of lymphoplasmacytic cells (LPC) in WM patients through expression of several ligands including CD40L, B-LYS, PDGFa and VEGF. While increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4a2a263b5731f2da3311e4a9f066332
https://doi.org/10.1182/blood.v106.11.980.980
https://doi.org/10.1182/blood.v106.11.980.980