Zobrazeno 1 - 10
of 156
pro vyhledávání: '"James M. Tepper"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The responses of striatal GABAergic interneurons to thalamic inputs are not well characterised. Here, the authors demonstrate that complex intrastriatal circuitry is responsible for thalamic-evoked monosynaptic and disynaptic excitation in NPY-NGF in
Externí odkaz:
https://doaj.org/article/d39cb425dee64c9493c7bbd8b6ab89fd
Autor:
Lynda Chin, Gordon B. Mills, Michael A. Davies, Kenneth Y. Tsai, Katherine Stemke-Hale, James M. Tepper, Zhuangna Fang, Guocan Wang, Giannicola Genovese, Tony Gutschner, Mozhdeh Mahdavi, Peter K. Cabeceiras, Liren Li, Ian R. Watson
Supplementary Table 1. (Top) IC50 (nM), fold changes (FC) and (Bottom) % viability at 10uM drug treatment compared to DMSO control for BRAF mutant cell lines, A375, MALME-3M, 451Lu and IGR1 (expresses RAC1 P29S) are shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c4d7dbf863237d4b842c67149416ac
https://doi.org/10.1158/0008-5472.22404083
https://doi.org/10.1158/0008-5472.22404083
Autor:
James M. Tepper, Tibor Koós, Osvaldo Ibanez-Sandoval, Fatuel Tecuapetla, Thomas W. Faust, Maxime Assous
Publikováno v:
Frontiers in Neuroanatomy, Vol 12 (2018)
Our original review, “Heterogeneity and Diversity of Striatal GABAergic Interneurons,” to which this is an invited update, was published in December, 2010 in Frontiers is Neuroanatomy. In that article, we reviewed several decades’ worth of anat
Externí odkaz:
https://doaj.org/article/5aec64dafb6a4902a6cbeef9e4778dc2
Autor:
Hussain Y. Khdour, Krishnakanth Kondabolu, Alina Khadka, Maxime Assous, James M. Tepper, Tracy S. Tran, Pierre-Olivier Polack
Publikováno v:
J Neurosci
The functions of cortical networks are progressively established during development by series of events shaping the neuronal connectivity. Synaptic elimination, which consists of removing the supernumerary connections generated during the earlier sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfe28a5d339929bcca70a43aae6e178
https://europepmc.org/articles/PMC9188426/
https://europepmc.org/articles/PMC9188426/
Cholinergic interneurons (CINs) are essential elements of striatal circuits and behaviors. While acetylcholine signaling via muscarinic receptors (mAChRs) have been well studied, more recent data indicate that postsynaptic nicotinic receptors (nAChRs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1094df81bee691936ba06b8b5d0f6c
https://doi.org/10.1101/2021.11.22.469580
https://doi.org/10.1101/2021.11.22.469580
Autor:
Jaime Kaminer, Tibor Koós, Diego Espinoza, Shaznaan Bhimani, Michael W. Shiflett, James M. Tepper
Publikováno v:
Eur J Neurosci
The striatum mediates a broad range of cognitive and motor functions. Within the striatum, recently discovered tyrosine hydroxylase expressing interneurons (THINs) provide a source of intrastriatal synaptic connectivity that is critical for regulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8abb906677e1fcf2df9d56e38f7766
https://doi.org/10.1111/ejn.14412
https://doi.org/10.1111/ejn.14412
Publikováno v:
The Journal of Neuroscience. 39:4727-4737
The main excitatory inputs to the striatum arising from the cortex and the thalamus innervate both striatal spiny projection neurons and interneurons. These glutamatergic inputs to striatal GABAergic interneurons have been suggested to regulate the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a084bb0d4cfa3720cdb0b9e346ef962
https://doi.org/10.1523/jneurosci.2913-18.2019
https://doi.org/10.1523/jneurosci.2913-18.2019
Autor:
James M Tepper
Publikováno v:
Frontiers in Systems Neuroscience, Vol 6 (2012)
Externí odkaz:
https://doaj.org/article/fab1bd21c6ee420e91ab5724196d46fc
Publikováno v:
Frontiers in Systems Neuroscience, Vol 5 (2011)
We have recently shown in vitro that striatal tyrosine hydroxylase-expressing interneurons identified in transgenic mice by expression of enhanced green fluorescent protein (TH-eGFP) display electrophysiological profiles that are distinct from those
Externí odkaz:
https://doaj.org/article/c8813d5045eb42d9b0236209fa7a022e
Publikováno v:
Frontiers in Neuroanatomy, Vol 4 (2010)
The canonical view of striatal GABAergic interneurons has evolved over several decades of neuroanatomical/neurochemical and electrophysiological studies. From the anatomical studies, 3 distinct GABAergic interneuronal subtypes are generally recognize
Externí odkaz:
https://doaj.org/article/e0fad10457a4434b97236c7c512f7d20