Zobrazeno 1 - 10
of 266
pro vyhledávání: '"James M. Shine"'
Autor:
Erin Neyhart, Na Zhou, Brandon R. Munn, Robert G. Law, Cameron Smith, Zakir H. Mridha, Francisco A. Blanco, Guochuan Li, Yulong Li, Ming Hu, Matthew J. McGinley, James M. Shine, Jacob Reimer
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114808- (2024)
Summary: Acetylcholine (ACh) is thought to play a role in driving the rapid, spontaneous brain-state transitions that occur during wakefulness; however, the spatiotemporal properties of cortical ACh activity during these state changes are still uncle
Externí odkaz:
https://doaj.org/article/71236ae5ac384762ada080f0663a773f
Autor:
Natasha L. Taylor, Christopher J. Whyte, Brandon R. Munn, Catie Chang, Joseph T. Lizier, David A. Leopold, Janita N. Turchi, Laszlo Zaborszky, Eli J. Műller, James M. Shine
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114359- (2024)
Summary: There is substantial evidence that neuromodulatory systems critically influence brain state dynamics; however, most work has been purely descriptive. Here, we quantify, using data combining local inactivation of the basal forebrain with simu
Externí odkaz:
https://doaj.org/article/e5e21a41678c43adb1066b669d3d5839
Autor:
Brandon R. Munn, Eli J. Müller, Vicente Medel, Sharon L. Naismith, Joseph T. Lizier, Robert D. Sanders, James M. Shine
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The human brain displays a rich repertoire of states that emerge from the microscopic interactions of cortical and subcortical neurons. Difficulties inherent within large-scale simultaneous neuronal recording limit our ability to link biophy
Externí odkaz:
https://doaj.org/article/d376d01b2d704a3eba5798f538f3e675
Autor:
Anouk Tosserams, Bastiaan R. Bloem, Kaylena A. Ehgoetz Martens, Rick C. Helmich, Roy P. C. Kessels, James M. Shine, Natasha L. Taylor, Gabriel Wainstein, Simon J. G. Lewis, Jorik Nonnekes
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-11 (2023)
Abstract In stressful or anxiety-provoking situations, most people with Parkinson’s disease (PD) experience a general worsening of motor symptoms, including their gait impairments. However, a proportion of patients actually report benefits from exp
Externí odkaz:
https://doaj.org/article/184865872cb74338a4b2872722a1dd8a
Autor:
Eli J. Müller, Brandon R. Munn, Michelle J. Redinbaugh, Joseph Lizier, Michael Breakspear, Yuri B. Saalmann, James M. Shine
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112844- (2023)
Summary: The neurobiological mechanisms of arousal and anesthesia remain poorly understood. Recent evidence highlights the key role of interactions between the cerebral cortex and the diffusely projecting matrix thalamic nuclei. Here, we interrogate
Externí odkaz:
https://doaj.org/article/046a429061f24698a31005a502326c55
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Although spontaneous brain activity is complex and clinically relevant, it is still unclear whether transitions in resting brain activity follow an underlying arrangement or whether they are unpredictable. In this work, the authors revealed a transit
Externí odkaz:
https://doaj.org/article/5cf8fb6bd7804fb7b16f52bcbcad623f
Autor:
Andrea I. Luppi, Joana Cabral, Rodrigo Cofre, Pedro A.M. Mediano, Fernando E. Rosas, Abid Y. Qureshi, Amy Kuceyeski, Enzo Tagliazucchi, Federico Raimondo, Gustavo Deco, James M. Shine, Morten L. Kringelbach, Patricio Orio, ShiNung Ching, Yonatan Sanz Perl, Michael N. Diringer, Robert D. Stevens, Jacobo Diego Sitt
Publikováno v:
NeuroImage, Vol 275, Iss , Pp 120162- (2023)
Disorders of consciousness are complex conditions characterised by persistent loss of responsiveness due to brain injury. They present diagnostic challenges and limited options for treatment, and highlight the urgent need for a more thorough understa
Externí odkaz:
https://doaj.org/article/fc2682b4006f431f83d6438f1b9584ed
Autor:
Elie Matar, Kaylena A. Ehgoetz Martens, Joseph R. Phillips, Gabriel Wainstein, Glenda M. Halliday, Simon J. G. Lewis, James M. Shine
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Cognitive fluctuations are a characteristic and distressing disturbance of attention and consciousness seen in patients with Dementia with Lewy bodies and Parkinson’s disease dementia. It has been proposed that fluctuations result from dis
Externí odkaz:
https://doaj.org/article/0108549a050b4014bd8934c74a298ba7
Autor:
Yohan J. John, Kayle S. Sawyer, Karthik Srinivasan, Eli J. Müller, Brandon R. Munn, James M. Shine
Publikováno v:
Network Neuroscience, Vol 6, Iss 4, Pp 960-979 (2022)
AbstractMost human neuroscience research to date has focused on statistical approaches that describe stationary patterns of localized neural activity or blood flow. While these patterns are often interpreted in light of dynamic, information-processin
Externí odkaz:
https://doaj.org/article/65908feb2c0c4d8ca7aa6446486c1667
Autor:
Kartik K. Iyer, Kai Hwang, Luke J. Hearne, Eli Muller, Mark D’Esposito, James M. Shine, Luca Cocchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
The study of the brain’s low-dimensional topology enables the dynamic tracking of changes in neural activity. Here authors show how the reshaping of low-dimensional trajectories of brain activity sustain cognition following focal neural perturbatio
Externí odkaz:
https://doaj.org/article/173c88548e4649fa8438041de6813647