Zobrazeno 1 - 10
of 11
pro vyhledávání: '"James M. Harkema"'
Autor:
Dean T. Nora, Luis H. Toledo-Pereyra, James M. Harkema, Richard E. Dean, Ben L. Bachulis, Fernando A. Rivera-Chavez, Gustavo Martínez-Mier
Publikováno v:
Journal of Investigative Surgery. 14:7-12
Hemorrhagic shock (HS) and resuscitation can be seen as a global body ischemia-reperfusion (I/R) injury characterized by neutrophil infiltration and organ damage. Liver dysfunction occurs early after HS. Adhesion molecules are needed for the first st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6733d53add943e0278d63990ba22eb2d
https://doi.org/10.1080/089419301750072167
https://doi.org/10.1080/089419301750072167
Autor:
Richard E. Dean, James M. Harkema, Timothy P. Kogan, Luis Horacio Toledo-Pereyra, Richard A.F Dixon, J. M. Palma-Vargas
Publikováno v:
Journal of the American College of Surgeons. 185:365-372
Background: The selectin family of adhesion molecules plays a key role in the neutrophil-mediated injury observed after ischemia and reperfusion. In our study, we investigated the effects of TBC-1269, a novel small-molecule, nonoligosaccharide inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc5d62792c9c2dfceb7dfee7dcea2b26
https://doi.org/10.1016/s1072-7515(01)00943-7
https://doi.org/10.1016/s1072-7515(01)00943-7
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 36:803-809
Although clinical studies suggest enteral, as opposed to parenteral, feeding lowers morbidity and mortality rates following severe trauma and after sepsis, it is unknown whether gut absorptive capacity (GAC) is indeed maintained under such conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ee826bc342d2e79cdfe6ae94478b9f
https://doi.org/10.1097/00005373-199406000-00009
https://doi.org/10.1097/00005373-199406000-00009
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 266:R368-R374
Although cardiac output (CO) and other hemodynamic variables are used to assess the adequacy of fluid resuscitation after hemorrhage, it is not known whether there is any correlation between restoration of CO and circulating blood volume (CBV). To de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec06b1409ebb9de2fcefb590e4c6b025
https://doi.org/10.1152/ajpregu.1994.266.2.r368
https://doi.org/10.1152/ajpregu.1994.266.2.r368
Publikováno v:
Journal of Critical Care. 7:189-216
The systemic inflammatory response to perfusion deficits, injury, and sepsis is characterized by a myriad of physiologic changes that appear to be mediated by numerous factors. It is not possible to implicate a single factor that is responsible for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844b253c7f760ca842c1542b9c425756
https://doi.org/10.1016/0883-9441(92)90016-z
https://doi.org/10.1016/0883-9441(92)90016-z
Publikováno v:
Journal of Critical Care. 5:62-69
Sepsis produces a characteristic hypermetabolic and hyperdynamic circulatory state. If this response is not reversed, multiple organ failure follows with a high mortality rate. The cellular dysfunction that results in overt organ failure is not clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda6b56e0d78d2a8e77fdaf967fa8f4d
https://doi.org/10.1016/0883-9441(90)90010-7
https://doi.org/10.1016/0883-9441(90)90010-7
Publikováno v:
Journal of surgical education. 64(2)
A 66-year-old white woman was found to have an elevated serum calcium and parathyroid hormone (PTH) on routine health evaluation. Physical examination was unremarkable as was ultrasonography of the neck. A sestamibi parathyroid scan revealed abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6094be32c359eed93b850b5fc52df62d
https://pubmed.ncbi.nlm.nih.gov/17462212
https://pubmed.ncbi.nlm.nih.gov/17462212
Autor:
Keith N. Apelgren, Carol A. Slomski, James M. Harkema, Amy B. Jentz, L. Rao Kareti, Cheryl I. Anderson
Publikováno v:
American journal of surgery. 189(3)
Background Accreditation Council for Graduate Medical Education (ACGME) competencies have increased the focus on education. A 1-year study of observational assessments was conducted. Methods “Point of Observation” evaluations were completed by fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7450c8271701cb48fd5d6500d02e246
https://pubmed.ncbi.nlm.nih.gov/15792752
https://pubmed.ncbi.nlm.nih.gov/15792752
Autor:
Irshad H. Chaudry, James M. Harkema
Publikováno v:
Developments in Cardiovascular Medicine ISBN: 9781461380566
The heart and other organs are dependent on aerobic metabolism. When the arterial blood flow is reduced to the point that insufficient oxygen is available for oxidative phosphorylation, the production of adenosine triphosphate (ATP) is decreased. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::108b6220419ef50c55d39cbe3149d693
https://doi.org/10.1007/978-1-4613-0455-5_16
https://doi.org/10.1007/978-1-4613-0455-5_16
Autor:
Irshad H. Chaudry, James M. Harkema
Publikováno v:
Critical care medicine. 20(2)
To review the rationale for adenosine triphosphate-magnesium chloride (ATP-MgCl2) administration in shock, ischemia, and sepsis; the beneficial effects on cellular and organ functions and survival; and possible mechanisms of these effects.Current lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd0bb330a67f047f8811af67f063746
https://pubmed.ncbi.nlm.nih.gov/1737460
https://pubmed.ncbi.nlm.nih.gov/1737460