Zobrazeno 1 - 10
of 44
pro vyhledávání: '"James M. Ertelt"'
Autor:
Zhengliang L. Wu, James M. Ertelt
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Enzymatic synthesis of fluorophore-labeled glycans and their usage of substrates reveals substrate specificities of endoglycosidases.
Externí odkaz:
https://doaj.org/article/caaa812359254012a5ae9be7c60f50f6
Autor:
Zhengliang L. Wu, James M. Ertelt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Glycosylation is the most common post-translational modification and has myriad of biological functions. However, glycan analysis has always been a challenge. Here, we would like to present new techniques for glycan fingerprinting based on e
Externí odkaz:
https://doaj.org/article/13dba3542f8b46a5b4e3fa63f8990015
Autor:
Vassili Kalabokis, James M. Ertelt, Zhengliang L. Wu, Whittaker Mark Russell, Anthony D Person
Publikováno v:
Glycobiology
Like sialylation, fucose usually locates at the nonreducing ends of various glycans on glycoproteins and constitutes important glycan epitopes. Detecting the substrate glycans of fucosyltransferases is important for understanding how these glycan epi
Autor:
James M. Ertelt, Zhengliang L. Wu
Publikováno v:
Glycobiology. 31(11)
Glycosaminoglycans (GAGs), such as hyaluronan (HA) and heparan sulfate (HS), are a large group of polysaccharides found in the extracellular matrix and on the cell surface. The turnover of these molecules is controlled by de novo synthesis and catabo
Autor:
Maria G. Winter, Sing Sing Way, Laura Taylor Alto, James M. Ertelt, Wesley B. Burford, Neal M. Alto, Sebastian E. Winter, Giang Pham, Li-Shu Zhang, Didi Chen
Publikováno v:
Cell Host Microbe
Summary The minimal genetic requirements for microbes to survive within multiorganism communities, including host-pathogen interactions, remain poorly understood. Here, we combined targeted gene mutagenesis with phenotype-guided genetic reassembly to
Autor:
Zhengliang L. Wu, James M. Ertelt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Glycosylation is the most common post-translational modification and has myriad of biological functions. However, glycan analysis has always been a challenge. Here, we would like to present new techniques for glycan fingerprinting based on enzymatic
Publikováno v:
Aging Cell
Summary Aging confers increased susceptibility to common pathogens including influenza A virus. Despite shared vulnerability to infection with advancing age in humans and rodents, the relatively long time required for immune senescence to take hold p
Autor:
Dayna R. Clark, Sing Sing Way, Lijun Xin, Jeremy M. Kinder, James M. Ertelt, Tony T. Jiang, Chaturvedi
Publikováno v:
Mucosal immunology
Mucosal Immunology
Mucosal Immunology
Commensal enteric bacteria maintain systemic immune responsiveness that protects against disseminated or localized infection in extra-intestinal tissues caused by pathogenic microbes. However, as shifts in infection susceptibility after commensal bac
Autor:
Sing Sing Way, Jeremy M. Kinder, James M. Ertelt, Aimen F. Shaaban, Lijun Xin, Beverly S. Strong, Tony T. Jiang
Publikováno v:
Chimerism
Compulsory exposure to genetically foreign maternal tissue imprints in offspring sustained tolerance to noninherited maternal antigens (NIMA). Immunological tolerance to NIMA was first described by Dr. Ray D. Owen for women genetically negative for e
Autor:
Lijun Xin, Tony T. Jiang, Sing Sing Way, Vandana Chaturvedi, James M. Ertelt, Helen Jones, Kathryn Owens, Jeremy M. Kinder
Publikováno v:
Journal of Clinical Investigation. 125:1713-1725
Mammalian pregnancy requires protection against immunological rejection of the developing fetus bearing discordant paternal antigens. Immune evasion in this developmental context entails silenced expression of chemoattractant proteins (chemokines), t