Zobrazeno 1 - 10
of 17
pro vyhledávání: '"James M. Eaton"'
Autor:
Robert T. Lawrence, Sankeerth Takkellapati, Garrett R. Mullins, Jennifer M. Pearson, Mitchell E. Granade, Salome Boroda, Samuel W. Entwisle, Thurl E. Harris, Judit Villén, James M. Eaton
Publikováno v:
Journal of Biological Chemistry. 292:20481-20493
Lipins 1, 2, and 3 are Mg2+-dependent phosphatidic acid phosphatases and catalyze the penultimate step of triacylglycerol synthesis. We have previously investigated the biochemistry of lipins 1 and 2 and shown that di-anionic phosphatidic acid (PA) a
Autor:
Sara L. Collier, Fong-Fu Hsu, Zhouji Chen, Sara K. Pittman, Scot J. Matkovich, Thurl E. Harris, George G. Schweitzer, Conrad C. Weihl, Brian N. Finck, Roman Chrast, Jun Yoshino, James M. Eaton, Kyle S. McCommis
Lipin 1 regulates glycerolipid homeostasis by acting as a phosphatidic acid phosphohydrolase (PAP) enzyme in the triglyceride-synthesis pathway and by regulating transcription factor activity. Mutations in human lipin 1 are a common cause of recurren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350ce036ee9194a8f9dfa48cbf144696
https://europepmc.org/articles/PMC6355067/
https://europepmc.org/articles/PMC6355067/
Autor:
Gwen Hwarng, Thurl E. Harris, Trisha J. Grevengoed, Rosalind A. Coleman, James M. Eaton, Viswanathan Natarajan, Daniel E. Cooper, Chongben Zhang
Publikováno v:
Journal of Biological Chemistry. 290:3519-3528
Although an elevated triacylglycerol content in non-adipose tissues is often associated with insulin resistance, the mechanistic relationship remains unclear. The data support roles for intermediates in the glycerol-3-phosphate pathway of triacylglyc
Autor:
Chongben Zhang, Trisha J. Grevengoed, Eric L. Klett, James M. Eaton, Lei O. Li, Thurl E. Harris, Rosalind A. Coleman, Daniel E. Cooper
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 307:E305-E315
Glycerol-3-phosphate acyltransferase (GPAT) activity is highly induced in obese individuals with insulin resistance, suggesting a correlation between GPAT function, triacylglycerol accumulation, and insulin resistance. We asked whether microsomal GPA
Autor:
Robert T. Lawrence, Judit Villén, Salome Boroda, Thurl E. Harris, Samantha G. Sherwood, Kelley E. McQueeney, James M. Eaton, Garrett R. Mullins, Brian N. Finck, Sankeerth Takkellapati
Publikováno v:
Journal of Biological Chemistry. 289:18055-18066
Lipin 2 is a phosphatidic acid phosphatase (PAP) responsible for the penultimate step of triglyceride synthesis and dephosphorylation of phosphatidic acid (PA) to generate diacylglycerol. The lipin family of PA phosphatases is composed of lipins 1-3,
Autor:
James M. Eaton, Deborah Lawrence
Publikováno v:
Forest Ecology and Management. 258:949-958
Cumulative losses from shifting cultivation in the tropics can affect the local to regional to global balance of carbon and nutrient cycles. We determined whether shifting cultivation in the Southern Yucatan causes feedbacks that limit future forest
Publikováno v:
Climatic Change. 91:317-334
Using both historic records and CORINE land cover maps, we assessed the impact of land cover change on the stock of soil organic carbon (SOC) in the Republic of Ireland from 1851 to 2000. We identified ten principal land cover classes: arable land, f
Autor:
Marcia DeLonge, Rishiraj Das, Deborah Lawrence, James M. Eaton, Lucy O. Diekmann, Paolo D'Odorico
Publikováno v:
Proceedings of the National Academy of Sciences. 104:20696-20701
The long-term ecological response to recurrent deforestation associated with shifting cultivation remains poorly investigated, especially in the dry tropics. We present a study of phosphorus (P) dynamics in the southern Yucatán, highlighting the pos
Autor:
Zhouji Chen, Robert C. Bucelli, Thurl E. Harris, Anne M. Connolly, Alan Pestronk, Sara L. Collier, James M. Eaton, George G. Schweitzer, Brian N. Finck
Publikováno v:
JIMD Reports ISBN: 9783662474662
Rhabdomyolysis is an acute syndrome due to extensive injury of skeletal muscle. Recurrent rhabdomyolysis is often caused by inborn errors in intermediary metabolism, and recent work has suggested that mutations in the human gene encoding lipin 1 (LPI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2b5b3f1f080b0184224261e9063ac4
https://doi.org/10.1007/8904_2015_440
https://doi.org/10.1007/8904_2015_440
Autor:
Deborah Lawrence, James M. Eaton
Publikováno v:
Forest Ecology and Management. 232:46-55
In Southern Mexico, shifting cultivation is creating a mosaic of agricultural lands, secondary forests, and disturbed mature forests (montanas). Increased land-use change, due to population and market pressures has changed the structure and function