Zobrazeno 1 - 10
of 55
pro vyhledávání: '"James M. Dominguez"'
Autor:
Kendal M Burstad, Dennis P Cladis, Colby J Vorland, Meryl E Wastney, Annabel Biruete, James M Dominguez II, Kalisha D O'Neill, Neal X Chen, Sharon M Moe, Kathleen M Hill Gallant
Publikováno v:
JBMR Plus, Vol 6, Iss 12, Pp n/a-n/a (2022)
ABSTRACT Dietary phosphorus restriction and phosphorus binders are commonly prescribed for patients with chronic kidney disease (CKD). However, occurrences of non‐adherence to these interventions are common. As low‐phosphorus (LP) diets have been
Externí odkaz:
https://doaj.org/article/f133f527981c440cb9771a8c9866340b
Autor:
James M Dominguez, Sharon M Moe, Neal X Chen, Todd O McKinley, Krista M Brown, Yunlong Liu, Hongyu Gao, Roman M Natoli
Publikováno v:
BioTechniques, Vol 71, Iss 2, Pp 431-438 (2021)
The ability to study the bone microenvironment of failed fracture healing may lead to biomarkers for fracture nonunion. Herein the authors describe a technique for isolating individual cells suitable for single-cell RNA sequencing analyses from intra
Externí odkaz:
https://doaj.org/article/cdd5b915484a40638d1700d57d37cbf7
Publikováno v:
American journal of physiology. Renal physiology. 323(5)
Ischemic acute kidney injury is common, deadly, and accelerates the progression of chronic kidney disease, yet has no specific therapy. After ischemia, reperfusion is patchy with early and persistent impairment in regional renal blood flow and cellul
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202550 (2018)
Hypoxic acute kidney injury, a major unresolved problem, initiates, or aggravates, renal functional and structural decline. There is no treatment for hypoxic acute renal injury and its sequelae. We tested the hypothesis that human kidney tubular cell
Externí odkaz:
https://doaj.org/article/f7f3606a33204c3196cd0d832a240138
Publikováno v:
Vascular Medicine. 26:585-594
Introduction: Increased oxidative stress is associated with vascular calcification in patients with chronic kidney disease (CKD). We have previously demonstrated that cellular-derived matrix vesicles (MV), but not media-derived MV, are endocytosed in
Autor:
Krista M Brown, Roman M. Natoli, Todd O. McKinley, Hongyu Gao, James M Dominguez, Neal X. Chen, Yunlong Liu, Sharon M. Moe
Publikováno v:
BioTechniques. 71:431-438
The ability to study the bone microenvironment of failed fracture healing may lead to biomarkers for fracture nonunion. Herein the authors describe a technique for isolating individual cells suitable for single-cell RNA sequencing analyses from intra
Single-cell RNAseq provides insight into altered immune cell populations in human fracture nonunions
Autor:
Keith G. Avin, James M. Dominguez, Neal X. Chen, Takashi Hato, Jered J. Myslinski, Hongyu Gao, Yunlong Liu, Todd O. McKinley, Krista M. Brown, Sharon M. Moe, Roman M. Natoli
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research SocietyREFERENCES.
Nonunion describes bone fractures that fail to heal, resulting in the fracture callus failing to fully ossify or, in atrophic cases, not forming altogether. Fracture healing is regulated, in part, by the balance of proinflammatory and anti-inflammato
Autor:
Vaishnavi Jadhav, Qianyi Luo, James M Dominguez, Jude Al-Sabah, Brahim Chaqour, Maria B Grant, Ashay D Bhatwadekar
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163367 (2016)
Period 2-mutant mice (Per2m/m), which possess a circadian dysfunction, recapitulate the retinal vascular phenotype similar to diabetic retinopathy (DR). The vascular dysfunction in Per2m/m is associated with an increase in connective tissue growth fa
Externí odkaz:
https://doaj.org/article/6d0bb7b96a7141a6b476ef6750b437fb
Publikováno v:
American Journal of Physiology: Renal Physiology; Nov2022, Vol. 323 Issue 5, pF590-F601, 12p
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111203 (2014)
BACKGROUND: This study determines 'correlation constants' between the gold standard histological measurement of retinal thickness and the newer spectral-domain optical coherence tomography (SD-OCT) technology in adult C57BL/6 mice. METHODS: Forty-eig
Externí odkaz:
https://doaj.org/article/4fad5fa1179649d5882a917c5d8e7080